Kim Hasenkrug is a Senior Investigator and Chief of the Retroviral Immunology Section at Rocky Mountain Laboratories, NIAID, NIH. Much of his work has used Friend virus-infected mice as a model to study acute and chronic retrovirus infections. Key discoveries include elucidation of the immunological requirements for B cells, CD4+ T cells and CD8+ T cells in vaccine-induced protection against acute and chronic retroviral infections. His lab also made the original discovery that viral infections induce immunosuppressive regulatory T cells. This led to similar findings in HIV and opened up a new field of study in infectious diseases. The Hasenkrug lab recently developed a new humanized mouse model in which to study HIV infections. This model is uniquely resistant to graft versus host disease and allows long-term HIV studies to test new HIV-1 therapeutics.
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