ICAAC in Washington, D.C. 2014
Researchers have created a synthetic DNA analog that can bind to and silence the gene responsible for NDM-1, a severe form of antibiotic resistance that can make some bacteria resistant to almost all antibiotics.
Recognizing the importance of the public health emergency of the Ebola outbreak in western Africa, the organizers of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) the annual infectious diseases meeting of the American Society for Microbiology (ASM) added 3 new presenters to the program to speak on the disease.
Rapid detection of antibiotic resistance is vital in assessing the appropriate antibiotic therapy for an infection. Participants present data on two new inexpensive tests to detect antibiotic resistance markers within hours or even minutes.
A newly developed antifungal, isavuconazole, is as effective as an existing drug, voriconazole against invasive mold disease in cancer patients with less adverse effects. Researchers present phase III data on this new drug.
An analysis of phase 2 and phase 3 clinical trials shows that a single injected dose of the neuraminidase inhibitor (NAI) paramivir is safe and effective at alleviating influenza symptoms including fever and viral shedding when administered within 48 hours of the onset of symptoms. Researchers present data on what may be the first new influenza drug in over a decade.