Funding Alert: Contact Congress for Emergency Funding for Zika

Please contact Congress to urge the immediate passage of a bipartisan emergency supplemental bill for Zika.
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ASM Acts to Counter Zika Virus Outbreak

The emerging threat of Zika virus infection.

ASM Urges Action to Combat Zika Emergency

Current events linked to the Zika virus make aggressive public health actions and funding to combat this emerging infectious disease more crucial than ever.
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denison mark

Dr. Mark Denison is Professor of Pediatrics, and Professor of Pathology, Microbiology, and Immunology at Vanderbilt University School of Medicine. Dr. Denison’s research is focused on the replication, cell biology, genetics, and evolution of the coronaviruses, a family of positive-strand RNA viruses with significant medical and veterinary importance.  The emergence of SARS coronavirus (SARS-CoV) demonstrated the potential of coronaviruses for severe human disease and zoonotic coronavirus epidemics or pandemics. The Denison Lab has made key discoveries on the viral replicase proteins that direct protein processing, host-cell modifications, and replication fidelity.  Dr. Denison and colleagues also have demonstrated the synthetic recovery of a non-cultivatable bat SARS-like coronavirus from genetic sequence only, which will allow testing of mechanisms of coronavirus host species movement. Most recently, his group has determined that a coronavirus protein, the nsp14 exonuclease, is required for faithful replication of the large coronavirus genome, and likely functions in RNA dependent RNA proofreading, previously unprecedented among RNA viruses.