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mcbride alison

Papillomaviruses are small DNA viruses that persistently infect and replicate in stratified cutaneous and mucosal epithelia. The viral DNA replicates and is maintained as low copy, extrachromosomal circular DNA molecules in dividing basal cells, which provide a reservoir of infected cells for the overlying virus producing tissue. The main focus of Dr. McBride’s research is understanding the mechanisms by which HPV genomes are successfully established, maintained and partitioned in persistently infected keratinocytes.


Dr. McBride is also the founder of the Papillomavirus Episteme, an online bioinformatics resource for papillomaviruses, http://pave.niaid.nih.gov/#home

 

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