New Compound Shows Promise Against Malaria
Washington, DC - June 6, 2016 - Malaria parasites cause hundreds of millions of infections, and kills hundreds of thousands of people annually, mostly in Africa. And in recent years the most dangerous malaria parasite, Plasmodium falciparum, has become increasingly resistant to the main anti-malarial drugs. Now, an international team of researchers shows that some members of a class of compounds called oxaboroles, which contain the element, boron, have potent activity against malaria parasites. The research is published ahead of print June 6 in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.
Crowds of Crows Spread C. jejuni: Are Humans Vulnerable?
Washington, DC - June 3, 2016 - Crows are smart, highly social animals that congregate in flocks of tens of thousands. Such large, highly concentrated populations can easily spread disease—not only amongst their own species, but quite possibly to humans, either via livestock, or directly. On the campus of the University of California, Davis, during winter, approximately half of the 6,000 American crows that congregated at the study site carried Campylobacter jejuni, which is the leading cause of gastroenteritis in humans in industrialized countries, which could contribute to the spread of disease. The research is published ahead of print June 3 in Applied and Environmental Microbiology.
Study Shows How Bacteria Evolve in the Lungs of Cystic Fibrosis Patients
Washington, DC – May 24, 2016 – The bacterium Burkholderia multivorans evolves and adapts in bursts to survive in the lungs of cystic fibrosis patients, according to a study published this week in mSystems, an open access journal from the American Society for Microbiology. The work, believed to be the first retrospective look at the evolution of this microorganism, indicates that B. multivorans directly or indirectly targets adherence, metabolism and changes to the cell ‘envelope’ to stick around and evade antibiotics.
Temperature Influences Gene Expression, Life Cycle in Vibrio cholerae
Washington, DC – May 20, 2016 – Vibrio cholerae infects roughly four million people annually, worldwide, causing severe diarrheal disease, and killing an estimated 140,000 people. Its success as a pathogen belies the challenges this bacterium faces. The waters this bacterium inhabits when it’s not infecting H. sapiens can be 40 degrees Fahrenheit cooler than our normal body temperature. Now a team of investigators from the University of California, Santa Cruz provides new insights into how different temperatures in the bacterium’s environment control expression of genes required for life at those temperatures. The research is published ahead of print May 20 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.
Probiotic Bacteria Could Provide Some Protection Against Cadmium Poisoning
Washington, DC - May 20, 2015 - Oral administration of certain probiotics reduced uptake of the heavy metal, cadmium, in the intestines of mice, and in a laboratory experiment using human intestinal cells. The research, which might ultimately be applied to improving public health in areas of heavy metal contamination, is published ahead of print May 20 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.
Antimicrobial in Common Toothpaste Doesn't Impact Gut, Oral Microbiome
Washington, DC - May 18, 2016 - Personal hygiene products such as soaps and toothpastes that contain the antibiotic triclosan do not have a major influence on microbial communities or endocrine function, according to a small, randomized trial. The study findings were published online May 18th in mSphere, an open-access journal of the American Society for Microbiology.
mBio Editorial Urges an Interdisciplinary Effort to Understand and Utilize Microbiomes, Solve Earth's Modern Challenges
Washington, DC – 6:00 am, May 13, 2016 – A guest editorial in mBio on Friday May 13th discusses the importance of a cross-disciplinary approach to studying earth’s microbiomes and calls for solutions to the challenges that lie ahead in microbiome research. The article titled ‘Toward a Predictive Understanding of Earth’s Microbiomes to Address 21st Century Challenges,’ urges scientists to harness the power of microorganisms collaboratively to address pressing, global 21st century challenges which threaten water, energy and food, ecosystems and the environment, as well as human health. This article highlights the issues being addressed by the National Microbiome Initiative launched by the White House Office of Science and Technology Policy.
Scientists Identify New Route of TB Transmission
Washington, DC - May 10, 2016 - Scientists have discovered a new species of bacteria, Mycobacterium mungi, that causes tuberculosis (TB) and is transmitted through the skin and nose of banded mongoose in Northern Botswana. The findings, published May 10 in the journal mBio, have radically changed scientists understanding of how tuberculosis can be transmitted.
Narrow Spectrum Antibiotic Kills Pathogens Without Killing Good Bacteria
Washington, DC - May 9, 2016 - The problem with broad spectrum antibiotics is that they kill good bacteria along with the bad. But a new antibiotic, Debio 1452, which is narrowly targeted at Staphilococcal pathogens, caused almost no harm to the gut microbiome of mouse models, while conventional broad spectrum antibiotics caused major damage. The research is published ahead of print May 9th in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.
Probiotics Mitigate Stress in Medical Students at Exam Time
Washington, DC - May 6, 2016 - A probiotic given to medical students during the run-up to nationwide medical school examinations reduced stress among the students. “The probiotic strain, Lactobacillus casei strain Shirota can relieve many aspects of the stress response, especially gastrointestinal dysfunction,” said corresponding author Kouji Miyazaki, PhD, director of the Food Research Department of Yakult Central Institute, Tokyo, Japan. The research is published ahead of print May 6th, in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.