Samuel Behar

Behar Samuel 250

After graduating from UC Berkeley and Albert Einstein College of Medicine, Samuel Behar pursued clinical training at Brigham and Women’s Hospital. There, he established his lab, and after 23 years, was recruited to the University of Massachusetts Medical School, where he is Professor of Microbiology and Physiological Systems. Dr. Behar studies immunity to Mycobacterium tuberculosis. His work spans the early events following macrophage infection to T cell priming, acquisition of effector function, and memory responses. He and his colleagues discovered how death of infected macrophages affects the outcome of infection and modulates both innate and acquired immunity. In addition, Dr. Behar’s lab has established an important role for CD8 T cells, elucidating their effector function and regulation during primary and memory responses. By understanding mechanisms of host resistance and bacterial evasion of immunity, he hopes to inform vaccine design.