Barbara Burleigh

Burleigh Barbara 250

Barbara Burleigh is a Professor of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health, where she studies the zoonotic protozoan parasite, Trypanosoma cruzi, the causative agent of human Chagas disease. T. cruzi is a highly adaptable parasite that exhibits a broad host range in nature with the capacity to colonize varied cell and tissue types in infected mammalian hosts. Dr. Burleigh's research program incorporates genomic, biochemical and cell biological approaches to study the complex biology that underlies T. cruzi parasitism with a focus on the permissive role of host metabolism in this process. The goal is to understand the degree of metabolic flexibility inherent in the host-parasite interaction and to leverage this knowledge for the development of novel therapeutic interventions that subvert pathogen survival strategies.