Frank Deleo

Deleo Frank 250

Frank DeLeo is Chief of the Laboratory of Bacteriology in the National Institute of Allergy and Infectious Diseases, National Institutes of Health. He received his Ph.D. from Montana State University, studying the molecular basis of superoxide generation by neutrophils. He did postdoctoral training in innate immunity and infectious diseases in the Department of Medicine at the University of Iowa. His laboratory studies pathogen-host interactions, with emphasis on the interaction of bacterial pathogens with human neutrophils and mechanisms of bacterial immune evasion. The long-term objective of his research is to promote development of enhanced diagnostics, better prophylactic agents, and new treatments for emerging or re-emerging bacterial pathogens. For example, work from his laboratory investigated the basis for the success of epidemic CA-MRSA in the U.S., including the role played by specific virulence molecules.