Robert Hausinger

Hausinger Robert 250

Robert P. Hausinger is a Professor of Microbiology & Molecular Genetics and Biochemistry & Molecular Biology at Michigan State University. His research uncovers microbial physiology related to the transition metals nickel and iron. He is a leader in studies that elucidate the nickel enzymes lactate racemase and urease, both of which require accessory proteins for syntheses of their distinct metallocenters: a modified pyridinium mononucleotide that binds nickel in a pincer species and a carbamate-bridged dinuclear site, respectively. His team also has characterized the importance of aldolase in the nickel toxicity in E. coli. In addition, the Hausinger laboratory has characterized numerous iron- and 2-oxoglutarate dependent oxygenases that function in DNA repair and the microbial metabolism of sulfonates, nucleobases, and herbicides. His work spans the interfaces of microbial biology, molecular biology, biochemistry, and inorganic chemistry.