Mark Connors talk about 2 different patient populations able to control HIV pathogenesis via their T cell or B cell responses.

Sunday, 18 November 2018 15:33

This old mouse - TWiV 520

Universal influenza vaccines that are in clinical trials, and discovery of an atypical parvovirus that causes chronic kidney disease in middle aged, immunocompromised laboratory mice.

Published in TWiV
Thursday, 15 November 2018 16:09

The Evolution of Virulence with Andrew Read

Andrew Read tells of his work demonstrating that a non-sterilizing vaccine allows pathogens to become even more virulent.

Sunday, 14 October 2018 14:11

When virus is in retrograde - TWiV 515

The passing of Tom Steitz, an outbreak of acute flaccid myelitis in the US, a continuing Ebola virus outbreak in DRC, respiratory vaccinia due to inhalation of ground up rabbit skin, and how a human papillomavirus capsid protein directs virus-containing endosomes towards the nucleus. 

Published in TWiV

Dr. Mair talks about why breaking the transmission cycle by focusing on mosquitoes will help reduce global malaria, how a multi-pronged approach is necessary to eradicate this disease, how public health efforts coordinating drug administration have been effective, and some of the hurdles that impede vaccine development.

Published in microTalk

To eliminate malaria, you have to stop transmission. Carolina Barillas-Mury discusses the co-evolution of malaria, mosquitos, and man.

Sunday, 16 September 2018 15:39

Accessory found guilty in DC - TWiV 511

Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.

Published in TWiV

The ongoing outbreak of Ebola virus in the Democratic Republic of the Congo, and the finding that mutations identified in the 2015 West African epidemic do not alter pathogenesis in animals. 

Published in TWiV

Recent mumps virus outbreaks in the US are due to waning vaccine efficacy, and an intranasally delivered small interfering RNA that controls West Nile infection in the brain.

Published in TWiV
Thursday, 08 February 2018 00:07

Rats, lice, and nanoparticles - TWiM 170

The spread of plague was likely due to human ectoparasites, not rats, and discussion of a durable, broadly protective protein nanoparticle influenza virus vaccine.

Published in TWiM
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