Applications of Clinical Microbial Next-Generation Sequencing, February 2016


Next-generation sequencing (NGS) has the capacity to provide crucial clinical benefits in patient care, patient outcomes, and public health, however, clinical laboratories must find ways to overcome operational, technical, regulatory, and strategic challenges in order to effectively employ NGS-based diagnostic tests. The Academy convened a colloquium on this topic in April 2015. Beyond the potential lifesaving impact of NGS methodologies, the report examines the main deterrents and shortcomings of the technology such as the data analysis and management pipelines, regulatory concerns and reimbursement issues, and the creation and maintenance of curated and secure databases. The report, titled Applications of Clinical Microbial Next-Generation Sequencing provides recommendations and suggestions for combating these current limitations to implementing NGS in clinical settings. 


View/Download this Report


We would welcome you sharing our report. If you do, please link to this page, and not the PDF.


The Academy hosted an event at the National Press Club in February 2016 to disseminate the report. A panel of 4 speakers discussed real world applications of NGS and findings from the report, followed by a brief question and answer session. The speakers were:

  • Stefano Bertuzzi, Ph.D., M.P.H., CEO of ASM
  • George Weinstock, Ph.D., Chair, Colloquium Steering Committee
  • Joseph Campos, Ph.D., ASM Secretary and Colloquium Participant
  • Charles Chiu, Ph.D., Colloquium Participant

This event was sponsored by bioMérieux and Illumina, Inc.


The event was recorded and is available to watch below.