ASM's Statement on the March for Science

March for Science Statement Graphic

ASM and Science Advocacy:

There is a widespread desire among scientists to be actively involved in science advocacy and societal issues. This is an opportune time for making science and scientists visible within society at large. The ASM has a strong tradition of engagement with policy issues, and it consistently supports its members in their advocacy for science that serves the public interest.

The March for Science:

A March for Science is being organized for April 22, Earth Day, in Washington DC. The mission statement and additional information can be found on the March for Science web page. A hope is that policy makers will take note of the value of science. ASM members might choose to participate in this march or concurrent events being planned for other cities, but it remains crucial that sustained, effective advocacy for science continues beyond these demonstrations.

ASM and Federal Policy on Science:

To inform and influence sound federal policy, the ASM and its members must repeatedly present clear, science based messages to policymakers and the broader public on the value of scientific knowledge that results from well funded research. Legislators are most receptive when they are contacted directly by constituents who succinctly express their views and focus on specific issues of the greatest importance to the largest number of voters. ASM has posted an advocacy page on its website to assist those members who wish to advocate for the microbial sciences.

ASM Response to White House Executive Order Regarding Travel and Immigration

ASM's mission is to promote and advance the microbial sciences through conferences and meetings that provide a forum for all scientists to come together and exchange scientific discovery. We recognize that diversity makes science stronger and collaboration across the globe is imperative for scientific advancements. ASM strives for an inclusive and welcoming environment and our goal is to provide a deeper understanding of the microbial sciences to diverse audiences. The participation of scientists from all countries and backgrounds is extremely important to our organization.

The recent White House Executive Order, if reinstated, could restrict scientists, students and postdoctoral fellows from attending ASM meetings. ASM remains committed towards inclusion of all attendees at its meetings.

Anyone affected who has submitted an abstract or registered for one of our upcoming conferences, but may no longer be able to attend the conference due to the Executive Order, should not hesitate to contact our Meeting Customer Service Department at 202.942.9250 or conferences@asmusa.org for assistance.

Volunteer and Governance Engagement Program Coordinator

The American Society for Microbiology (ASM), headquartered in Washington, DC, is seeking a full-time Volunteer and Governance Engagement Program Coordinator in the Office of the Executive Director department. The incumbent will be responsible for volunteer leadership and governance support, organizational governance nomination, appointments, and recruitment activities and coordinating the annual election of volunteer leadership positions for the Office of the Executive Director. In addition, the incumbent will be responsible for preparing and tracking budget for the volunteer leadership and governance activities.

ASM's Support of International Scientists

Dear Member,

You are receiving this email because you are an ASM member living in a country that is being affected by the January 27 White House Executive Order on immigration that bars the entry or return of individuals to the U.S. We are actively working with policy makers to end the adverse effects it is having on the ability of researchers and students to study, attend conferences, and collaborate with counterparts in the United States.

We support all our global members. We are proud of how highly engaged and dedicated you are in advancing the microbial sciences as well as preventing and curing infectious diseases that threaten millions worldwide. The ASM AmbassadorsYoung Ambassadors and BioResource Centers in your country have been actively providing education and microbiology skills building opportunities and will continue to do so. You will also have access to our online resources as before.

ASM is your professional society and a global home for your science. We recognize that diversity makes science stronger and collaboration across the globe is imperative for scientific advancements. The latest bLogphase post underlines all the dangers we face when we close our borders to global science.

SusieSharpNew     bertuzzi

Susan E. Sharp                                Stefano Bertuzzi, CEO, ASM    

Premium +1

For a limited time, the first 400 members who renew at the Premium member rate will be given one free membership* to award to the student, postdoc, or colleague of their choice. Hurry and renew!  The offer is only good for the first 400 members who renew, and all must be received by October 15, 2016.

HOW IT WORKS:

1)  You renew your membership at the Premium level before 10/15/16.

2)   Within 2 business days of processing your renewal you will receive an email with an application attached. 

3)  You select your recipient and forward the application for them to complete and return to ASM.  Please note:  all awarded membership applications must be received by November 15, 2016.

THE RULES:

-*Only Student, Postdoc, or Supporting memberships are included in this offer.
- Recipients cannot have been a member during 2016.
- The offer is first-come, first-served: when 400 applications have been awarded the offer will conclude.
- Each Premium member is eligible to receive only one free membership.
- The free membership cannot be used in combination with any other ASM product to receive a discount, or as part of a Lab & Classroom group.
- If are a 2016 Contributing Member and would like to upgrade to Premium in order to take advantage of this offer, either change your member type on the renewal form, and enter $132 for  payment OR select Premium membership when renewing online at www.asmscience.org/renew.

Questions?  Contact membership@asmusa.org

 

 

ASM is Your Global Society

Dear Members,

The ASM is as deeply concerned as you are about the January 27 White House Executive Order on immigration that bars the entry or return of individuals from certain countries and we are working with policy makers to end the adverse effects it is having on the ability of researchers to study and exchange knowledge. ASM prides itself on being a global community and our strength lies in both our national and international members.


We want to send a strong message of support to all our dedicated members worldwide who are working to prevent and cure infectious diseases that threaten global health. ASM is your professional society and a global home for your science. We recognize that diversity makes science stronger and collaboration across the globe is imperative for scientific advancements. The latest bLogphase post underlines all the dangers we face when we close our borders to global science.

SusieSharpNew    bertuzzi

Susan E. Sharp, President             Stefano Bertuzzi, CEO, ASM

 

How long does the grant writing process take?

How well do you know the grant writing process?

For a successful grant application, the typical time from submission to funding is:

a. 1-2 months
b. 3-4 months
c. 5-6 months
d. 7-8 months
e. 9-10 months

The typical length of the grant writing process, from when you begin planning your application to when you receive the funds, is 9-10 months. Since the grant process takes a significant amount of time and has important future implications, it is important to utilize all available resources. One such resource is the ASM Grant Writing Online Course. This three month, six-part webinar series provides graduate, postdoctoral sciences and early to mid-career scientists with an overview of the NIH and NSF grant process. Led by individuals who have successfully obtained grants, this course will provide participants with a broad understanding of (i) the grant making enterprise and the overall funding landscape, (ii) tips for successfully writing NIH and NSF grants, (iii) developing an impactful NIH/NSF Biosketch, and (iv) viewing your grant from the reviewer's perspective. 

Register here
Registration deadline: December 1, 2016
January - March 2017
ASM members: $150 | Non-members: $200

ASM on U.S. Immigration Policy Concerns

ASM on U.S. Immigration Policy Concerns

The mission of the ASM is to promote and advance the microbial sciences, in the United States and worldwide. The Society does not participate in partisan politics and maintains strict political neutrality on issues.

The ASM is deeply concerned about the White House Executive Order on immigration that bars the entry or return of individuals from certain countries and we are working with policy makers to end the adverse effects it is having on the ability of researchers to study and exchange knowledge. ASM prides itself on being a global community and our strength lies in both our national and international members.

 We want to send a strong message of support to all our dedicated members worldwide who are working to prevent and cure infectious diseases that threaten global health. ASM is your professional society and a global home for your science. We recognize that diversity makes science stronger and collaboration across the globe is imperative for scientific advancements. The latest bLogphase post underlines all the dangers we face when we close our borders to global science. 

 

SusieSharpNew                  stefano signature

Susan E. Sharp, President, ASM           Stefano Bertuzzi, CEO, ASM

 

ASM's Action Items on Immigration Policy:

The Dangers of Closing the Borders on Global Science

ASM and 150 Partner Organizations Urge Administration to rescind White House Executive Order on Immigration

ASM Letter to President Trump Regarding Immigration Executive Order

Immigration and Visa Information

ASM is Your Global Society

ASM's Support of International Scientists

 

bioRxiv (static HTML)

Genome Integration and Reactivation of the Virophage MavirusIn the Marine Protozoan Cafeteria roenbergensis

AUTHORS

Fischer, M. G. | Hackl, T. |

ABSTRACT

Endogenous viral elements are increasingly found in eukaryotic genomes, yet little is known about their origins, dynamics, or function. Here, we provide a compelling example of a DNA virus that readily integrates into a eukaryotic genome where it acts as an inducible antiviral defense system. We found that the virophage mavirus, a parasite of the giant virus CroV, integrates at multiple sites within the nuclear genome of the marine heterotrophic nanoflagellate Cafeteria roenbergensis. The endogenous mavirus is structurally and genetically similar to the eukaryotic Maverick/Polinton DNA transposons. Provirophage genes are activated by superinfection with CroV, which leads to the production of infectious mavirus particles. While provirophage-carrying cells are not directly protected from lysis by CroV, release of reactivated virophage particles promotes survival of other host populations. Our results corroborate the connection between mavirus and Maverick/Polinton elements and suggest that provirophages can defend natural protist populations against infection by giant viruses.

DOI: http://dx.doi.org/10.1101/068312

PUBLISHED: 2016-08-07

Generated MeSH Terms

Animals | DNA Transposable Elements | Parasites | Eukaryota | Superinfection | SERPINA3 protein, human | Serpins | Viruses | DNA Viruses | Antiviral Agents |

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21385722 | 23701946 | 24973308 | 21559486 | 26305943 | 20974979 | 24747414 | 26560305 | 23071316 | 24882428


Direct correlation between motile behavior and protein abundance in single cells

AUTHORS

Dufour, Y. S. | Gillet, S. | Frankel, N. W. | Weibel, D. B. | Emonet, T. |

ABSTRACT

Understanding how stochastic molecular fluctuations affect cell behavior requires the quantification of both behavior and protein numbers in the same cells. Here, we combine automated microscopy with in situ hydrogel polymerization to measure single-cell protein expression after tracking swimming behavior. We characterized the distribution of non-genetic phenotypic diversity in Escherichia coli motility, which affects single-cell exploration. By expressing fluorescently tagged chemotaxis proteins (CheR and CheB) at different levels, we quantitatively mapped motile phenotype (tumble bias) to protein numbers using thousands of single-cell measurements. Our results disagreed with established models until we incorporated the role of CheB in receptor deamidation and the slow fluctuations in receptor methylation. Beyond refining models, our central finding is that changes in numbers of CheR and CheB affect the population mean tumble bias and its variance independently. Therefore, it is possible to adjust the degree of phenotypic diversity of a population by adjusting the global level of expression of CheR and CheB while keeping their ratio constant, which, as shown in previous studies, confers functional robustness to the system. Since genetic control of protein expression is heritable, our results suggest that non-genetic diversity in motile behavior is selectable, supporting earlier hypotheses that such diversity confers a selective advantage.

DOI: http://dx.doi.org/10.1101/067918

PUBLISHED: 2016-08-04

Generated MeSH Terms

Methylation | Escherichia coli | Microscopy | Polymerization | Hydrogel | Swimming | Chemotaxis | Gene Expression Regulation | 5-(2-cyclohexylidene-ethyl)-5-ethylbarbiturate | Barbiturates | Phenotype | Genetic Variation |

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16788185 | 11717272 | 21292743 | 20972792 | 3056911 | 2188960 | 2661528 | 10464232 | 19231145 | 9465023


Rapid resistome mapping using nanopore sequencing

AUTHORS

van der Helm, E. | Imamovic, L. | Hashim Ellabaan, M. M. | Koza, A. | Sommer, M. O. A. O. A. |

ABSTRACT

The emergence of antibiotic resistance in human pathogens has become a major threat to modern medicine and in particular hospitalized patients. The outcome of antibiotic treatment can be affected by the composition of the gut resistome either by enabling resistance gene acquisition of infecting pathogens or by modulating the collateral effects of antibiotic treatment on the commensal microbiome. Accordingly, knowledge of the gut resistome composition could enable more effective and individualized treatment of bacterial infections. Yet, rapid workflows for resistome characterization are lacking. To address this challenge we developed the poreFUME workflow that deploys functional metagenomic selections and nanopore sequencing to resistome mapping. We demonstrate the approach by functionally characterizing the gut resistome of an ICU patient. The accuracy of the poreFUME pipeline is >97 % sufficient for the reliable annotation of antibiotic resistance genes. The poreFUME pipeline provides a promising approach for efficient resistome profiling that could inform antibiotic treatment decisions in the future.

DOI: http://dx.doi.org/10.1101/067652

PUBLISHED: 2016-08-03

Generated MeSH Terms

Humans | Workflow | Nanopores | Drug Resistance, Microbial | Microbiota | Metagenomics | Bacterial Infections | Anti-Bacterial Agents | Intensive Care Units |

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26419330 | 24710024 | 25918444 | 25247417 | 23370726 | 22827799 | 24474281 | 24236055 | 22936781 | 22954750


Experimental estimation of the effects of all amino-acid mutations to HIV Env

AUTHORS

Haddox, H. K. | Dingens, A. S. | Bloom, J. |

ABSTRACT

HIV is notorious for its capacity to evade immunity and anti-viral drugs through rapid sequence evolution. Knowledge of the functional effects of mutations to HIV is critical for understanding this evolution. HIV's most rapidly evolving protein is its envelope (Env). Here we use deep mutational scanning to experimentally estimate the effects of all amino-acid mutations to Env on viral replication in cell culture. Most mutations are under purifying selection in our experiments, although a few sites experience strong selection for mutations that enhance HIV's growth in cell culture. We compare our experimental measurements of each site's preference for each amino acid to the actual frequencies of these amino acids in naturally occurring HIV sequences. Our measured amino-acid preferences correlate with amino-acid frequencies in natural sequences for most sites. However, our measured preferences are less concordant with natural amino-acid frequencies at surface-exposed sites that are subject to pressures absent from our experiments such as antibody selection. We show that some regions of Env have a high inherent tolerance to mutation, whereas other regions (such as epitopes of broadly neutralizing antibodies) have a significantly reduced capacity to tolerate mutations. Overall, our results help disentangle the role of inherent functional constraints and external selection pressures in shaping Env's evolution.

DOI: http://dx.doi.org/10.1101/067470

PUBLISHED: 2016-08-02

Generated MeSH Terms

Antibodies, Neutralizing | Epitopes | Antiviral Agents | Amino Acids | Genes, env | HIV Infections | Virus Replication | Mutation |

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18177204 | 19096508 | 24713822 | 25006036 | 17534408 | 26506369 | 8995670 | 23468626 | 10364320 | 22073263


Small molecules with antibiofilm, antivirulence and antibiotic synergy activities against Pseudomonas aeruginosa.

AUTHORS

van Tilburg Bernardes, E. | Charron-Mazenod, L. | Reading, D. | Reckseidler-Zenteno, S. L. | Lewenza, S. |

ABSTRACT

Biofilm formation is a universal bacterial strategy for long-term survival in nature and during infections. Biofilms are dense microbial communities enmeshed within a polymeric extracellular matrix that protects bacteria from antibiotic exposure and the immune system and thus contribute to chronic infections. Pseudomonas aeruginosa is an archetypal biofilm-forming organism that utilizes a biofilm growth strategy to cause chronic lung infections in Cystic Fibrosis (CF) patients. The extracellular matrix of P. aeruginosa biofilms is comprised mainly of exopolysaccharides (EPS) and DNA. Both mucoid and non-mucoid isolates of P. aeruginosa produces the Pel and Psl EPS, each of which have important roles in antibiotic resistance, biofilm formation and immune evasion. Given the central importance of the Pel and Psl EPS in biofilm structure, they are attractive targets for novel anti-infective compounds. In this study we used a high throughput gene expression screen to identify compounds that repress expression of pel and psl genes as measured by transcriptional lux fusions. Testing of the pel/psl repressors demonstrated an antibiofilm activity against microplate and flow chamber biofilms formed by wild type and hyperbiofilm forming strains. To determine the potential role of EPS in virulence, mutants in pel/psl were shown to have reduced virulence in the feeding behavior and slow killing virulence assays in Caenorhabditis elegans. The antibiofilm molecules also reduced P. aeruginosa PAO1 virulence in the nematode slow killing model. Importantly, the combination of antibiotics and antibiofilm compounds were synergistic in killing P. aeruginosa biofilms. These small molecules represent a novel anti-infective strategy for the possible treatment of chronic P. aeruginosa infections.

DOI: http://dx.doi.org/10.1101/067074

PUBLISHED: 2016-08-01

Generated MeSH Terms

Animals | Humans | Pseudomonas aeruginosa | Biofilms | Anti-Bacterial Agents | Caenorhabditis elegans | Virulence | Cystic Fibrosis | Immune Evasion | Drug Resistance, Microbial | Anti-Infective Agents | Biological Processes | Physiological Processes | DNA | Extracellular Matrix | Immune System | Feeding Behavior |

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21605307 | 22176658 | 24595142 | 22309106 | 21666010 | 22309122 | 25096883 | 21298031 | 21998591 | 22585230


Stochastic Assembly Produces Heterogeneous Communities in the C. elegans Intestine

AUTHORS

Vega, N. | Gore, J. |

ABSTRACT

Host-associated bacterial communities vary extensively between individuals, but it can be very difficult to determine the sources of this heterogeneity. Here we demonstrate that stochastic bacterial community assembly in the C. elegans intestine is sufficient to produce strong inter-worm heterogeneity in community composition. When worms are fed with two neutrally-competing fluorescently labeled bacterial strains, we observe stochastically-driven bimodality in community composition, where approximately half of the worms are dominated by each bacterial strain. A simple model incorporating stochastic colonization suggests that heterogeneity between worms is driven by the low rate at which bacteria successfully establish new intestinal colonies. We can increase this rate experimentally by feeding worms at high bacterial density; in these conditions the bimodality disappears. These results demonstrate the potential importance of stochastic processes in bacterial community formation and suggest a role for C. elegans as a model system for ecology of host-associated communities.

DOI: http://dx.doi.org/10.1101/067173

PUBLISHED: 2016-08-01

Generated MeSH Terms

Animals | Caenorhabditis elegans | Stochastic Processes | Ecology | Intestines | Bacteria |

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24449749 | 23462114 | 23812817 | 21608478 | 23407312 | 24489823 | 23613815 | 22452899 | 22276219 | 26699734


Cohort Specific Effects of Cereal-bar Supplementation in Overweight Patients With or Without Type 2 Diabetes Mellitus

AUTHORS

Lauber, C. | Chou, C. J. | Chakrabarti, A. | Siddharth, J. | Chalut-Carpentier, A. | Pataky, Z. | Golay, A. | Parkinson, S. |

ABSTRACT

The importance of gut microbes to metabolic health is becoming more evident and nutrition-based therapies to alter the composition of bacterial communities to manage metabolic disease are an attractive avenue to ameliorate some effects of Western diets. While the composition of gut microbial communities can vary significantly across disease states, it is not well known if these communities have common responses to nutritional interventions. To better understand diet-bacterial community interactions, we collected biological parameters and fecal samples of overweight non-diabetic (OND) and diabetic (OD) individuals before and after daily supplementation of 2.8 g {beta}-glucan on their habitual diet for 30 days. Fecal bacterial communities in an age-matched cohort were measured by sequencing partial 16S rRNA genes and imputed metagenomic content. Unexpectedly, we observed disconnected responses of biological measurements and the bacterial community. Based on average effect size, biological measurements were greater in the OND group while effects on the bacterial community were greatest on the OD cohort, and we suspect these observations are due to the significantly lower alpha diversity in the OD cohort. Our data indicate that responses to cereal-bar supplementation are cohort specific and this should be considered when manipulating the microbiome via diet supplementation.

DOI: http://dx.doi.org/10.1101/066704

PUBLISHED: 2016-07-29

Generated MeSH Terms

Humans | Edible Grain | Diet, Western | RNA, Ribosomal, 16S | Diabetes Mellitus, Type 2 | Metagenomics | Microbiota | Overweight | Glucans |

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25271941 | 25954902 | 18974945 | 20368178 | 26039313 | 26147095 | 19706296 | 26066038 | 19043404 | 21121044


Capture of Vibrio cholerae by charged polymers inhibits pathogeniciy by inducing a sessile lifestyle

AUTHORS

Perez-Soto, N. | Moule, L. | Crisan, D. N. | Insua, I. | Taylor-Smith, L. M. | Voelz, K. | Fernandez-Trillo, F. | Krachler, A. |

ABSTRACT

Vibrio cholerae, the causative agent of cholera, is an abundant environmental bacterium that can efficiently colonize the intestinal tract and trigger severe diarrheal illness. Motility, and the production of colonization factors and cholera toxin, are fundamental for the establishment of disease. In the aquatic environment, V. cholerae persists by forming avirulent biofilms on zooplankton, phytoplankton and chitin debris. Here, we describe the formation of artificial, biofilm-like communities, driven by exposure of planktonic bacteria to synthetic polymers. This recruitment is extremely rapid and charge-driven, and leads to the formation of initial 'seed clusters' which then recruit additional bacteria to extend in size. Bacteria that become entrapped in these 'forced communities' undergo transcriptional changes in motility and virulence genes, and phenotypically mimic features of environmental biofilm communities by forming a matrix that contains polysaccharide and extracellular DNA. As a result of this lifestyle transition, pathogenicity and in vivo host colonization decrease. These findings highlight the potential of synthetic polymers to disarm pathogens by modulating their lifestlye, without creating selective pressure favoring the emergence of antimicrobial resistant strains.

DOI: http://dx.doi.org/10.1101/066563

PUBLISHED: 2016-07-28

Generated MeSH Terms

Animals | Vibrio cholerae | Cholera | Cholera Toxin | Virulence | Zooplankton | Biofilms | Plankton | Phytoplankton | Chitin | Polymers | Anti-Infective Agents | Intestines | DNA | Polysaccharides | Biological Processes | Life Style |

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25368110 | 16267135 | 19933826 | 24375135 | 22354023 | 16359328 | 14536065 | 22710417 | 22032623 | 22106284


Sequence based prediction of novel domains in the cellulosome of Ruminiclostridium thermocellum

AUTHORS

Basharat, Z. | Yasmin, A. |

ABSTRACT

Ruminiclostridium thermocellum strain ATCC 27405 is valuable with reference to the next generation biofuel production being a degrader of crystalline cellulose. The completion of its genome sequence has revealed that this organism carries 3,376 genes with more than hundred genes encoding for enzymes involved in cellulysis. Novel protein domain discovery in the cellulose degrading enzyme complex of this strain has been attempted to understand this organism at molecular level. Streamlined automated methods were employed to generate possibly unreported or new domains. A set of 12 novel Pfam-B domains was developed after detailed analysis. This finding will enhance our understanding of this bacterium and its molecular processes involved in the degradation of cellulose. This approach of in silico analysis prior to experimentation facilitates in lab study. Previously uncorrelated data has been utilized for rapid generation of new biological information in this study.

DOI: http://dx.doi.org/10.1101/066357

PUBLISHED: 2016-07-27

Generated MeSH Terms

Cellulosomes | Biofuels | Cellulose | Clostridium thermocellum | Protein Structure, Tertiary | Multienzyme Complexes | Base Sequence |

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12625841 | 20662379 | 21672225 | 19384422 | 21526192 | 1490597 | 21255373 | 25956772 | 20307315 | 23176123


A Novel Family of Genomics Islands Across Multiple Species of Streptococcus

AUTHORS

Wang, J. | Wang, C. | Feng, W. | Feng, Y. | Zhi, L. | Li, W. | Yao, Y. | Jiang, S. | Tang, J. |

ABSTRACT

The genus Streptococcus is one of the most genomically diverse and important human and agricultural pathogens. The acquisition of genomic islands (GIs) plays a central role in adaptation to new hosts in the genus pathogens. The research presented here employs a comparative genomics approach to define a novel family of GIs in the genus Streptococcus which also appears across strains of the same species. Specifically, we identified 9 Streptococcus genomes out of 67 sequenced genomes analyzed, and we termed these as 15bp Streptococcus genomic islands, or 15SGIs, including i) insertion adjacent to the 3' end of ribosome l7/l12 gene, ii) large inserts of horizontally acquired DNA, and iii) the presence of mobility genes (integrase) and replication initiators. We have identified a novel family of 15SGIs and seems to be important in species differentiation and adaptation to new hosts. It plays an important role during strain evolution in the genus Streptococcus.

DOI: http://dx.doi.org/10.1101/065920

PUBLISHED: 2016-07-26

Generated MeSH Terms

Humans | Genomic Islands | Integrases | Genomics | Biological Evolution | Streptococcus | DNA | Ribosomes |

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23096693 | 17475002 | 22306813 | 21672261 | 23204461 | 18071028 | 21536150 | 24977706 | 25009843 | 20826944


Microbial Communities are Well Adapted to Disturbances in Energy Input

AUTHORS

Fernandez-Gonzalez, N. | Huber, J. A. | Vallino, J. J. |

ABSTRACT

Although microbial systems are well-suited for studying concepts in ecological theory, little is known about how microbial communities respond to long-term periodic perturbations beyond diel oscillations. Taking advantage of an ongoing microcosm experiment, we studied how methanotrophic microbial communities adapted to disturbances in energy input over a 20 day cycle period. Sequencing of bacterial 16S rRNA genes together with quantification of microbial abundance and ecosystem function was used to explore the long-term dynamics (510 days) of methanotrophic communities under continuous versus cyclic chemical energy supply. We observed that microbial communities appear inherently well-adapted to disturbances in energy input and that changes in community structure in both treatments are more dependent on internal dynamics than on external forcing. Results also show that the rare biosphere is critical to seeding the internal community dynamics, perhaps due to cross-feeding or other strategies. We conclude that in our experimental system, endogenous feedbacks were more important than exogenous drivers in shaping the community dynamics over time, suggesting that ecosystems can maintain their function despite inherently unstable community dynamics. IMPORTANCE Within the broader ecological context, biological communities are often viewed as stable and only experience succession or replacement when subject to external perturbations, such as changes in food availability or introduction of exotic species. Our findings indicate that microbial communities can exhibit strong internal dynamics that may be more important in shaping community succession than external drivers. Dynamic "unstable" communities may be important for ecosystem functional stability, with rare organisms playing an important role in community restructuring. Understanding the mechanisms responsible for internal community dynamics will certainly be required for understanding and manipulating microbiomes in both host-associated and natural ecosystems.

DOI: http://dx.doi.org/10.1101/066050

PUBLISHED: 2016-07-26

Generated MeSH Terms

RNA, Ribosomal, 16S | Biota | Microbiota | Ecology |

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25028427 | 24732211 | 23462114 | 24926862 | 23985743 | 18043612 | 12755711 | 22530997 | 22286988 | 19030917


S2 from Equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3

AUTHORS

Chande, A. | Cuccurullo, E. | Rosa, A. | Ziglio, S. | Carpenter, S. | Pizzato, M. |

ABSTRACT

The lentivirus equine infectious anemia virus (EIAV) encodes S2, a pathogenic determinant important for virus replication and disease progression in horses. No molecular function has yet been linked to this accessory protein. We now report that S2 can replace the activity of Nef on HIV-1 infectivity, being required to antagonize the inhibitory activity of SERINC proteins on Nef-defective HIV-1. Similar to Nef, S2 excludes SERINC5 from virus particles and requires an ExxxLL motif predicted to recruit the clathrin adaptor AP2. Accordingly, a functional endocytic machinery is essential for S2-mediated infectivity enhancement, which is impaired by inhibitors of clathrin-mediated endocytosis. In addition to retargeting SERINC5 to a late endosomal compartment, S2 promotes the host factor degradation. Emphasizing the similarity with Nef, we show that S2 is myristoylated and, compatible with a crucial role of the post-translational modification, its N-terminal glycine is required for the anti-SERINC5 activity. EIAV-derived vectors devoid of S2 are less susceptible than HIV-1 to the inhibitory effect of both human and equine SERINC5. We then identified the envelope glycoprotein of EIAV as a determinant which also modulates retrovirus susceptibility to SERINC5, indicating a bi-modular ability of the equine lentivirus to counteract the host factor. S2 shares no sequence homology with other retroviral factors known to counteract SERINC5. Adding to primate lentivirus Nef and gammaretrovirus glycoGag, the accessory protein from EIAV makes another example of a retroviral virulence determinant which independently evolved SERINC5-antagonizing activity. SERINC5 therefore plays a critical role for the interaction of the host with diverse retrovirus pathogens.

DOI: http://dx.doi.org/10.1101/065078

PUBLISHED: 2016-07-21

Generated MeSH Terms

Humans | Horses | Animals | Infectious Anemia Virus, Equine | HIV-1 | Lentiviruses, Primate | Virion | Lentivirus | Gammaretrovirus | Retroviridae | Lentiviruses, Equine | Protein Processing, Post-Translational | Glycine | Virulence | Equidae | Virus Replication | HIV Infections | Sequence Homology | Endocytosis | Disease Progression | Clathrin | Adaptor Proteins, Vesicular Transport |

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26416734 | 26416733 | 10590152 | 20417672 | 17267500 | 16503341 | 15539516 | 19769166 | 25390683 | 18057237


Understanding How Microbiomes Influence the Systems they Inhabit: Insight from Ecosystem Ecology

AUTHORS

Hall, E. | Bernhardt, E. | Bier, R. | Bradford, M. | Boot, C. | Cotner, J. | del Giorgio, P. | Evans, S. | Graham, E. | Jones, S. | Lennon, J. | Locey, K. | Nemergut, D. | Osborne, B. | Rocca, J. | Schimel, J. | Waldrop, M. | Wallenstein, M. |

ABSTRACT

The well-documented significance of microorganisms to the function of virtually all ecosystems has led to the assumption that more information on microbiomes will improve our ability to understand and predict system-level processes. Notably, the importance of the microbiome has become increasingly evident in the environmental sciences and in particular ecosystem ecology. However, translating the ever-increasing wealth of information on environmental microbiomes to advance ecosystem science is proving exceptionally challenging. One reason for this challenge is that correlations between microbiomes and the ecosystem processes they influence are often reported without the underlying causal mechanisms. This limits the predictive power of each correlation to the time and place at which it was identified. In this paper, we assess the assumptions and approaches currently used to establish links between environmental microbiomes and the ecosystems they influence, propose a framework to more effectively harness our understanding of microbiomes to advance ecosystem science, and identify key challenges and solutions required to apply the proposed framework. Specifically, we suggest identifying each microbial process that contributes to the ecosystem process of interest a priori. We then suggest linking information on microbial community membership through microbial community properties (such as biomass elemental ratios) to the microbial processes that drive each ecosystem process (e.g. N -mineralization). A key challenge in this framework will be identifying which microbial community properties can be determined from the constituents of the community (community aggregated traits, CATs) and which properties are unable to be predicted from a list of their constituent taxa (emergent properties, EPs). We view this directed approach as a promising pathway to advance our understanding of how microbiomes influence the systems they inhabit.

DOI: http://dx.doi.org/10.1101/065128

PUBLISHED: 2016-07-21

Generated MeSH Terms

Biomass | Ecology | Microbiota |

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26200800 | 26422463 | 26378320 | 20662931 | 26380076 | 18695234 | 23462114 | 21272182 | 26207269 | 25880923


Impact of Sample Type and DNA Isolation Procedure on Genomic Inference of Microbiome Composition

AUTHORS

Knudsen, B. E. | Bergmark, L. | Munk, P. | Lukjancenko, O. | Prieme, A. | Aarestrup, F. M. | Pamp, S. J. |

ABSTRACT

Explorations of complex microbiomes using genomics greatly enhance our understanding about their diversity, biogeography, and function. The isolation of DNA from microbiome specimens is a key prerequisite for such examinations, but challenges remain in obtaining sufficient DNA quantities required for certain sequencing approaches, achieving accurate genomic inference of microbiome composition, and facilitating comparability of findings across specimen types and sequencing projects. These aspects are particularly relevant for the genomics-based global surveillance of infectious agents and antimicrobial resistance from different reservoirs. Here, we compare a total of eight DNA extraction procedures for three specimen types (human feces, pig feces, hospital sewage), assess DNA extraction using spike-in controls and different types of beads for bead-beating facilitating cell lysis. We evaluate DNA concentration, purity, and stability, and microbial community composition using 16S rRNA gene sequencing and for selected samples using shotgun metagenomic sequencing. Our results suggest that inferred community composition was dependent on inherent specimen properties as well as DNA extraction method. We further show that bead-beating or enzymatic treatment can increase the extraction of DNA from Gram-positive bacteria. Final DNA quantities could be increased by isolating DNA from a larger volume of cell lysate compared to standard protocols. Based on this insight, we have designed an improved DNA isolation procedure optimized for microbiome genomics that can be used for the three examined specimen types and potentially also for other biological specimens.

DOI: http://dx.doi.org/10.1101/064394

PUBLISHED: 2016-07-18

Generated MeSH Terms

Humans | Animals | Swine | Sewage | RNA, Ribosomal, 16S | Anti-Infective Agents | Metagenomics | Microbiota | DNA | Genomics | Feces | Bacteria |

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26094313 | 22457796 | 23844068 | 25880246 | 20140796 | 25548939 | 25257543 | 25798612 | 24884524 | 25549184


MICROWAVE MUTAGENESIS OF BREVIBACILLUS PARABREVIS FOR ENHANCED CELLULASE PRODUCTION, AND INVESTIGATION ON THERMOSTABILITY OF THIS CELLULASE

AUTHORS

Khambhala, P. | Paliwal, P. | Kothari, V. |

ABSTRACT

Microwave mutagenesis of Brevibacillus parabrevis for enhanced cellulase production was attempted. Though microwave treatment could alter the cellulase activity of the test bacterium, none of the mutants obtained were found to be genetically stable, indicating the reversible nature of microwave-induced mutation(s). Thermal stability of the B. parabrevis cellulase was also investigated. This enzyme was found to be capable of retaining its activity even after heat treatment (50-121{degrees}C, for 30-60 min). Fluorescence spectrum revealed a red shift in the emission maxima of the heat-treated enzyme preparations, indicating some structural change upon heating, but no major loss of activity was observed. This enzyme was found to be active over a broad temp range, with 90{degrees}C as the optimum temp, which is interesting as the producing organism is a mesophile.

DOI: http://dx.doi.org/10.1101/064410

PUBLISHED: 2016-07-18

Generated MeSH Terms

Cellulase | Heating | Microwaves | Brevibacillus | Fluorescence | Hot Temperature | Temperature | Hyperthermia, Induced | Mutagenesis | Mutation |

Related Articles

19656667 | 12153 | 19859753 | 25886936 | 11272024 | 780122 | 11854 | 19711200 | 11341679 | 15659186


Comparative phylogenetic analysis of bacterial associates in Pyrrhocoroidea and evidence for ancient and persistent environmental symbiont reacquisition in Largidae (Hemiptera: Heteroptera).

AUTHORS

Gordon, E. R. L. | McFrederick, Q. S. | Weirauch, C. |

ABSTRACT

The ancient insect order Hemiptera, one of the most well-studied insect lineages with respect to bacterial symbioses, still contains major branches which lack robust phylogenies and comprehensive characterization of associated bacterial symbionts. The Pyrrhocoroidea (Largidae [220 species]; Pyrrhocoridae [~300 species]) is a superfamily of the primarily-herbivorous hemipteran infraorder Pentatomomorpha, though relationships to related superfamilies are controversial. Studies on bacterial symbionts of this group have focused on members of Pyrrhocoridae, but recent examination of species of two genera of Largidae demonstrated divergent symbiotic complexes between these putative sister families. We surveyed bacterial diversity of this group using paired-end Illumina and targeted Sanger sequencing of bacterial 16S amplicons of 30 pyrrhocoroid taxa, including 17 species of Largidae, in order to determine the identity of bacterial associates and similarity of associated microbial communities among species. We also constructed the first comprehensive phylogeny of this superfamily (4,800 bp; 5 loci; 57 ingroup + 12 outgroup taxa) in order accurately trace the evolution of symbiotic complexes among Pentatomomorpha. We undertook multiple lines of investigation (i.e., experimental rearing, FISH microscopy, phylogenetic and co-evolutionary analyses) to understand potential transmission routes of largid symbionts. We found a prevalent, specific association of Largidae with plant-beneficial-environmental clade Burkholderia housed in midgut tubules. As in other distantly-related Heteroptera, symbiotic bacteria seem to be acquired from the environment every generation. We review current understanding of symbiotic complexes within the Pentatomomorpha and discuss means to further investigations of the evolution and function of these symbioses. Importance. Obligate symbioses with bacteria are common in insects, particularly for Hemiptera wherein varied forms of symbiosis occur, though knowledge of symbionts remains incomplete for major lineages. Thus, an accurate understanding of how these partnerships evolved and changed over millions of years is not yet achievable. We contribute to our understanding of the evolution of symbiotic complexes in Hemiptera by characterizing bacterial associates of Pyrrhocoroidea focusing on the family Largidae and by constructing a phylogeny to establish evolutionary relationships of and within this group. Members of Largidae are associated with specific symbiotic Burkholderia from a different clade than Burkholderia symbionts in other Hemiptera and are members of the earliest-diverging superfamily of Burkholderia-associated Hemiptera. Evidence suggests that species of Largidae reacquire specific symbiotic bacteria every generation environmentally, a rare strategy for insects with potentially volatile evolutionary ramifications, but one that has persisted in Largidae and other related lineages since the Cretaceous.

DOI: http://dx.doi.org/10.1101/064022

PUBLISHED: 2016-07-15

Generated MeSH Terms

Animals | Female | Heteroptera | Phylogeny | Symbiosis | Burkholderia | Siblings | Microscopy | Biological Evolution | Herbivory | Residence Characteristics |

Related Articles

26023876 | 25521625 | 19146674 | 20882057 | 23574391 | 26116716 | 21385056 | 23949857 | 23691052 | 26045536


Recent Outbreaks of Shigellosis in California Caused by Two Distinct Populations of Shigella sonnei With Increased Virulence or Fluoroquinolone Resistance

AUTHORS

Kozyreva, V. K. | Jospin, G. | Greninger, A. | Watt, J. P. | Eisen, J. A. | Chaturvedi, V. |

ABSTRACT

Shigella sonnei has caused unusually large outbreaks of shigellosis in California in 2014 - 2015. Preliminary data indicated the involvement of two distinct yet related bacterial populations, one from San Diego and San Joaquin (SD/SJ) and one from the San Francisco (SF) Bay area. Whole genome sequencing of sixty-eight outbreak and archival isolates of S. sonnei was performed to investigate the microbiological factors related to these outbreaks. Both SD/SJ and SF populations, as well as almost all of the archival S. sonnei isolates belonged to sequence type 152 (ST152). Genome-wide SNP analysis clustered the majority of California (CA) isolates to an earlier described global Lineage III, which has persisted in CA since 1986. Isolates in the SD/SJ population had a novel Shiga-toxin (STX)-encoding lambdoid bacteriophage, most closely related to that found in an Escherichia coli O104:H4 strain responsible for a large outbreak. However, the STX genes (stx1a and stx1b) from this novel phage had sequences most similar to the phages from S. flexneri and S. dysenteriae. The isolates in the SF population yielded evidence of fluoroquinolone resistance acquired via the accumulation of point mutations in gyrA and parC genes. Thus, the CA S. sonnei lineage continues to evolve by the acquisition of increased virulence and antibiotic resistance, and enhanced monitoring is advocated for its early detection in future outbreaks.

DOI: http://dx.doi.org/10.1101/063818

PUBLISHED: 2016-07-14

Generated MeSH Terms

Shigella sonnei | Dysentery, Bacillary | Shiga Toxin | Virulence | San Francisco | Point Mutation | Escherichia coli | Bays | Drug Resistance, Microbial | Fluoroquinolones | Bacteriophages | Disease Outbreaks |

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11705937 | 23390901 | 22858547 | 19297378 | 23341549 | 11699845 | 9623912 | 3049838 | 17587439 | 20947666


Microbial Mat Functional and Compositional Sensitivity to Environmental Disturbance

AUTHORS

Preisner, E. C. | Fichot, E. B. | Norman, R. S. |

ABSTRACT

The ability of ecosystems to adapt to environmental perturbations depends on the duration and intensity of change and the overall biological diversity of the system. While studies have indicated that rare microbial taxa may provide a biological reservoir that supports long-term ecosystem stability, how this dynamic population is influenced by environmental parameters remains unclear. In this study, a microbial mat ecosystem located on San Salvador Island, The Bahamas was used as a model to examine how environmental disturbance affects the activity of rare and abundant archaeal and bacterial communities and how these changes impact potential biogeochemical processes. While this ecosystem undergoes a range of seasonal variation, it experienced a large shift in salinity (230 to 65 g kg-1) during 2011-2012 following the landfall of Hurricane Irene on San Salvador Island. High throughput sequencing and analysis of 16S rRNA and rRNA genes from samples before and after the pulse disturbance showed significant changes in the diversity and activity of abundant and rare taxa, suggesting overall functional and compositional sensitivity to environmental change. In both archaeal and bacterial communities, while the majority of taxa showed low activity across conditions, the total number of active taxa and overall activity increased post-disturbance, with significant shifts in activity occurring among abundant and rare taxa across and within phyla. Broadly, following the post-disturbance reduction in salinity, taxa within Halobacteria decreased while those within Crenarchaeota, Thaumarchaeota, Thermoplasmata, Cyanobacteria, and Proteobacteria, increased in abundance and activity. Quantitative PCR of genes and transcripts involved in nitrogen and sulfur cycling showed concomitant shifts in biogeochemical cycling potential. Post-disturbance conditions increased the expression of genes involved in N-fixation, nitrification, denitrification, and sulfate reduction. Together, our findings show complex community adaptation to environmental change and help elucidate factors connecting disturbance, biodiversity, and ecosystem function that may enhance ecosystem models.

DOI: http://dx.doi.org/10.1101/063370

PUBLISHED: 2016-07-12

Generated MeSH Terms

Archaea | Nitrification | Nitrogen | RNA, Ribosomal, 16S | Crenarchaeota | Denitrification | Sulfur | Seasons | Euryarchaeota | Salinity | Proteobacteria | Halobacterium | Cyclonic Storms | Bahamas | Genes, rRNA | Biodiversity | Ecosystem | Cyanobacteria | Islands | Polymerase Chain Reaction | Sulfates |

Related Articles

25028427 | 25781013 | 24704080 | 26474747 | 17298358 | 23254515 | 25912922 | 22194288 | 25423027 | 26283343


Benzoate and Salicylate Tolerant Strains Lose Antibiotic Resistance during Laboratory Evolution of Escherichia coli K-12

AUTHORS

Creamer, K. | Ditmars, F. | Basting, P. J. | Acero, S. | Kunka, K. S. | Hamdallah, I. | Bush, S. P. | Scott, Z. | He, A. | Penix, S. | Gonzales, A. | Eder, E. K. | Camperchioli, D. | Berndt, A. | Clark, M. W. | Rouhier, K. | Slonczewski, J. L. |

ABSTRACT

Escherichia coli K-12 W3110 grows in the presence of membrane-permeant organic acids that can depress cytoplasmic pH and accumulate in the cytoplasm. We conducted laboratory evolution by daily dilution in increasing concentrations of benzoic acid (from 5 to 20 mM) buffered at external pH 6.5, a pH at which permeant acids concentrate in the cytoplasm. By 2,000 generations, clones isolated from the evolving populations showed change in phenotype from benzoate-sensitive to benzoate-tolerant but sensitive to chloramphenicol and tetracycline. Sixteen clones isolated at 2,000 generations grew to stationary phase in 20 mM benzoate, whereas the ancestral strain W3110 peaked and declined. Similar growth profiles were seen in 10 mM salicylate. The strains showed growth profiles indistinguishable from W3110 in the absence of benzoate; in media buffered at pH 4.8, pH 7.0, or pH 9.0; or in 20 mM acetate or sorbate at pH 6.5. The genomes of 16 strains revealed over 100 mutations including SNPs, large deletions, and insertion sequence knockouts. Most strains acquired deletions in the benzoate-induced multiple antibiotic resistance (Mar) regulon or associated regulators such as rob and cpx, as well as MDR efflux pumps emrA, emrY, and mdtA. Strains also lost or down-regulated the Gad acid fitness regulon. In 5 mM benzoate, or in 2 mM salicylate, most strains showed increased sensitivity to the antibiotic chloramphenicol, some more sensitive than a marA knockout. Thus, the benzoate-evolved strains may reveal additional unknown drug resistance components. Benzoate is a common food preservative, and salicylate is the primary active metabolite of aspirin. In the gut microbiome, genetic adaptation to salicylate may involve loss or downregulation of inducible multidrug resistance systems. This discovery implies that aspirin therapy may modulate the human gut microbiome to favor salicylate tolerance at the expense of drug resistance.

DOI: http://dx.doi.org/10.1101/063271

PUBLISHED: 2016-07-11

Generated MeSH Terms

Tetracycline | Chloramphenicol | Benzoic Acid | Food Preservatives | DNA Transposable Elements | Aspirin | Escherichia coli | Benzoates | Escherichia coli K12 | Regulon | Down-Regulation | Gastrointestinal Microbiome | Polymorphism, Single Nucleotide | Drug Resistance, Microbial | Salicylates | Anti-Bacterial Agents | Acids | Phenotype | Drug Resistance, Multiple | Mutation | Acetates |

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25556191 | 7504664 | 3909154 | 20011599 | 15496390 | 2954947 | 21541325 | 9097440 | 1537798 | 11257026


Molecular and biological characterization of an isolate of Tomato mottle mosaic virus (ToMMV) infecting tomato and other experimental hosts in a greenhouse in Valencia, Spain

AUTHORS

Ambros, S. | Martinez, F. | Ivars, P. | Hernandez, C. | de la Iglesia, F. | Elena, S. F. |

ABSTRACT

Tomato is known to be a natural and experimental reservoir host for many plant viruses. In the last few years a new tobamovirus species, Tomato mottle mosaic virus (ToMMV), has been described infecting tomato and pepper plants in several countries worldwide. Upon observation of symptoms in tomato plants growing in a greenhouse in Valencia, Spain, we aimed to ascertain the etiology of the disease. Using standard molecular techniques, we first detected a positive sense single-stranded RNA virus as the probable causal agent. Next, we amplified, cloned and sequenced a ~3 kb fragment of its RNA genome which allowed us to identify the virus as a new ToMMV isolate. Through extensive assays on distinct plant species, we validated Koch's postulates and investigated the host range of the ToMMV isolate. Several plant species were locally and/or systemically infected by the virus, some of which had not been previously reported as ToMMV hosts despite they are commonly used in research greenhouses. Finally, two reliable molecular diagnostic techniques were developed and used to assess the presence of ToMMV in different plants species. We discuss the possibility that, given the high sequence homology between ToMMV and Tomato mosaic virus, the former may have been mistakenly diagnosed as the latter by serological methods.

DOI: http://dx.doi.org/10.1101/063255

PUBLISHED: 2016-07-11

Generated MeSH Terms

Tobamovirus | Lycopersicon esculentum | Host Specificity | RNA | Spain | Base Sequence | Plant Viruses | Sequence Homology | Piper nigrum | Molecular Diagnostic Techniques | RNA Viruses |

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14579173 | 22080188 | 21853328 | 24390328 | 19768650 | 26239043 | 19423673 | 20470828 | 22523958 | 23064695


An ex vivo lung model to study bronchioles infected with Pseudomonas aeruginosa biofilms

AUTHORS

Harrison, F. | Diggle, S. P. |

ABSTRACT

A key aim in microbiology is to determine the genetic and phenotypic bases of bacterial virulence, persistence and antimicrobial resistance in chronic biofilm infections. This requires tractable, high-throughput models that reflect the physical and chemical environment encountered in specific infection contexts. Such models will increase the predictive power of microbiological experiments and provide platforms for enhanced testing of novel antibacterial or antivirulence therapies. We present an optimised ex vivo model of cystic fibrosis lung infection: ex vivo culture of pig bronchiolar tissue in artificial cystic fibrosis mucus. We focus on the formation of biofilms by Pseudomonas aeruginosa. We show highly repeatable and specific formation of biofilms that resemble clinical biofilms by a commonly-studied lab strain and ten cystic fibrosis isolates of this key opportunistic pathogen.

DOI: http://dx.doi.org/10.1101/063222

PUBLISHED: 2016-07-11

Generated MeSH Terms

Animals | Swine | Pseudomonas aeruginosa | Cystic Fibrosis | Biofilms | Anti-Bacterial Agents | Bronchioles | Virulence | Anti-Infective Agents | Mucus | Pseudomonas Infections | Lung | Sus scrofa |

Related Articles

26506004 | 16207991 | 21998591 | 17116883 | 25448466 | 11048725 | 22309106 | 26253522 | 17224667 | 25477303


Origins of pandemic clones from environmental gene pools

AUTHORS

Shapiro, B. J. | Levade, I. | Kovacikova, G. | Taylor, R. K. | Almagro-Moreno, S. |

ABSTRACT

Some microbes can transition from an environmental lifestyle to a pathogenic one. This ecological switch typically occurs through the acquisition of horizontally acquired virulence genes. However, the genomic features that must be present in a population prior to the acquisition of virulence genes and emergence of pathogenic clones remain unknown. We hypothesized that virulence adaptive polymorphisms (VAPs) circulate in environmental populations and are required for this transition. We developed a comparative genomic framework for identifying VAPs, using Vibrio cholerae as a model. We then characterized several environmental VAP alleles to show that one of them reduced the ability of clinical strains to colonize a mammalian host, whereas two other alleles conferred efficient colonization. These results show that VAPs are present in environmental bacterial populations prior to the emergence of virulent clones. We propose a scenario in which VAPs circulate in the environment, they become selected and enriched under certain ecological conditions, and finally a genomic background containing several VAPs acquires virulence factors that allows for its emergence as a pathogenic clone.

DOI: http://dx.doi.org/10.1101/063115

PUBLISHED: 2016-07-10

Generated MeSH Terms

Animals | Vibrio cholerae | Virulence | Alleles | Virulence Factors | Gene Pool | Pandemics | Ecology | Genomics | Mammals | Life Style |

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14766976 | 18462070 | 23076327 | 19319196 | 11939579 | 22676367 | 14607067 | 15728357 | 10024551 | 21078967


Metabolic Reconstruction and Modeling Microbial Electrosynthesis

AUTHORS

Marshall, C. | Ross, D. | Handley, K. | Weisenhorn, P. | Edirisinghe, J. | Henry, C. | Gilbert, J. | May, H. | Norman, R. S. |

ABSTRACT

Microbial electrosynthesis is a renewable energy and chemical production platform that relies on microbial taxa to capture electrons from a cathode and fix carbon. Yet the metabolic capacity of multispecies microbial communities on electrosynthetic biocathodes remains unknown. We assembled 13 genomes from a high-performing electroacetogenic culture, and mapped their transcriptional activity from a range of conditions. This allowed us to create a metabolic model of the primary community members (Acetobacterium, Sulfurospirillum, and Desulfovibrio). Acetobacterium was the primary carbon fixer, and a keystone member of the community. Based on transcripts upregulated near the electrode surface, soluble hydrogenases and ferredoxins from Acetobacterium and hydrogenases, formate dehydrogenase, and cytochromes of Desulfovibrio were essential conduits for electron flow from the electrode into the electrosynthetic community. A nitrogenase gene cluster with an adjacent ferredoxin and one of two Rnf complexes within the genome of the Acetobacterium were also upregulated on the electrode. Nitrogenase is known to serve as a hydrogenase, thereby it would contribute to hydrogen production by the biocathode. Oxygenases of microaerobic members of the community throughout the cathode chamber, including Sulfurospirillum and Rhodobacteraceae, were expressed. While the reactors were maintained anaerobically, this gene expression would support anaerobic growth and thus electrosynthesis by scrubbing small amounts of O2 out of the reactor. These molecular discoveries and metabolic modeling now serve as a foundation for future examination and development of electrosynthetic microbial communities.

DOI: http://dx.doi.org/10.1101/059410

PUBLISHED: 2016-07-07

Generated MeSH Terms

Acetobacterium | Hydrogenase | Ferredoxins | Formate Dehydrogenases | Desulfovibrio | Electrons | Rhodobacteraceae | Nitrogenase | Carbon | Oxygenases | Electrodes | Renewable Energy | Biological Processes | Up-Regulation | Multigene Family | Hydrogen | Cytochromes |

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23676111 | 23001672 | 26399888 | 26079858 | 24910339 | 17353934 | 18284174 | 23603672 | 24126154 | 25333313


Characterization of the effects of n-butanol on the cell envelope of E. coli

AUTHORS

Fletcher, E. | Pilizota, T. | Davies, P. R. | McVey, A. | French, C. E. |

ABSTRACT

Biofuel alcohols have severe consequences on the microbial hosts used in their biosynthesis, which limits the productivity of the bioconversion. The cell envelope is one of the most strongly affected structures, in particular, as the external concentration of biofuels rises during biosynthesis. Damage to the cell envelope can have severe consequences, such as impairment of transport into and out of the cell; however the nature of butanol-induced envelope damage has not been well characterized. In the present study, the effects of n-butanol on the cell envelope of Escherichia coli were investigated. Using enzyme and fluorescence-based assays, we observed that 1% v/v n-butanol resulted in release of lipopolysaccharides from the outer membrane of E. coli and caused leakiness in both outer and inner membranes. Higher concentrations of n-butanol, within the range of 2% - 10% (v/v), resulted in inner membrane protrusion through the peptidoglycan observed by characteristic blebs. The findings suggest that strategies for rational engineering of butanol-tolerant bacterial strains should take into account all components of the cell envelope.

DOI: http://dx.doi.org/10.1101/062547

PUBLISHED: 2016-07-07

Generated MeSH Terms

1-Butanol | Peptidoglycan | Escherichia coli | Lipopolysaccharides | Biofuels | Alcohols | Fluorescence | Blister | Butanols | Cell Membrane | Cell Wall | Biological Transport |

Related Articles

24056459 | 21408113 | 20118358 | 6630230 | 22898718 | 2045784 | 24014527 | 6415062 | 24967819 | 17506684


The clinically approved antiviral drug sofosbuvir impairs Brazilian zika virus replication

AUTHORS

Sacramento, C. Q. | de Melo, G. R. | Rocha, N. | Hoelz, L. V. B. | Mesquita, M. | de Freitas, C. S. | Fintelman-Rodrigues, N. | Marttorelli, A. | Ferreira, A. C. | Barbosa-Lima, G. | Bastos, M. M. | Volotao, E. d. M. | Tschoeke, D. A. | Leomil, L. | Bozza, F. A. | Bozza, P. T. | Boechat, N. | Thompson, F. L. | de Filippis, A. M. B. | Bruning, K. | Souza, T. |

ABSTRACT

Zika virus (ZIKV) is a member of Flaviviridae family, as other agents of clinical significance, such as dengue (DENV) and hepatitis C (HCV) viruses. ZIKV spread from Africa to Pacific and South American territories, emerging as an etiological pathogen of neurological disorders, during fetal development and in adulthood. Therefore, antiviral drugs able to inhibit ZIKV replication are necessary. Broad spectrum antivirals, such as interferon, ribavirin and favipiravir, are harmful for pregnant animal models and women. The clinically approved uridine nucleotide analog anti-HCV drug, sofosbuvir, has not been affiliated to teratogenicity. Sofosbuvir target the most conserved protein over the members of the Flaviviridae family, the viral RNA polymerase. We thus studied ZIKV susceptibility to sofosbovir. We initially characterized a Brazilian ZIKV strain for use in experimental assays. Sofosbuvir inhibits the Brazilian ZIKV replication in a dose-dependent manner, both in BHK-21 cells and SH-Sy5y, by targeting ZIKV RNA polymerase activity, with the involvement of conserved amino acid residues over the members of Flaviviridae family. The identification of clinically approved antiviral drugs endowed with anti-ZIKV could reduce the time frame in pre-clinical development. Altogether, our data indicates that sofosbuvir chemical structure is endowed with anti-ZIKV activity.

DOI: http://dx.doi.org/10.1101/061671

PUBLISHED: 2016-07-06

Generated MeSH Terms

Humans | Animals | Female | Antiviral Agents | Ribavirin | Interferons | Sofosbuvir | RNA, Viral | favipiravir | Uridine | Zika Virus | Hepatitis C Antibodies | Hepacivirus | Hepatitis C | Amides | Pyrazines | DNA-Directed RNA Polymerases | Dengue | Amino Acids | Virus Replication | Models, Animal | Fetal Development | Nervous System Diseases | Africa | Brazil |

Related Articles

26085147 | 26283013 | 26294237 | 19788800 | 26527535 | 25822283 | 24148652 | 22389730 | 22953014 | 25175944


General calibration of microbial growth in microplate readers

AUTHORS

Stevenson, K. | McVey, A. F. | Clark, I. B. N. | Swain, P. S. | Pilizota, T. |

ABSTRACT

Optical density (OD) measurements of microbial growth are one of the most common techniques used in microbiology, with applications ranging from antibiotic efficacy studies, studies of growth under different nutritional or stress environments, to studies of different mutant strains, including those harbouring synthetic circuits. OD measurements are performed under the assumption that the OD value obtained is proportional to the cell number, i.e. the concentration of the sample. However, the assumption holds true in a limited range of conditions and calibration techniques that determine that range are currently missing. Here we present a set of calibration procedures and considerations that are necessary to successfully estimate the cell concentration from OD measurements.

DOI: http://dx.doi.org/10.1101/061861

PUBLISHED: 2016-07-04

Generated MeSH Terms

Calibration | Biological Processes | Physiological Processes | Cell Count | Research | Anti-Bacterial Agents |

Related Articles

17061075 | 22280888 | 16313423 | 24654390 | 4005611 | 10624324 | 19726895 | 21509987 | 23016461 | 22947163


Dysregulation of Long Non-coding RNA (lncRNA) Genes and Predicted lncRNA-protein Interactions during Zika Virus Infection

AUTHORS

Ramaiah, A. | Contreras, D. | Gangalapudi, V. | Padhye, M. S. | Tang, J. | Arumugaswami, V. |

ABSTRACT

Zika Virus (ZIKV) is a causative agent for poor pregnancy outcome and fetal developmental abnormalities, including microcephaly and eye defects. As a result, ZIKV is now a confirmed teratogen. Understanding host-pathogen interactions, specifically cellular perturbations caused by ZIKV, can provide novel therapeutic targets. In order to complete viral replication, viral pathogens control the host cellular machineries and regulate various factors, including long non-coding RNA (lncRNA) genes, at transcriptional levels. The role of lncRNA genes in the pathogenesis of ZIKV-mediated microcephaly and eye defects is currently unknown. To gain additional insights, we focused on profiling the differentially expressed lncRNA genes during ZIKV infection in mammalian cells. For this study, we employed a contemporary clinical Zika viral isolate, PRVABC59, of Asian genotype. We utilized an unbiased RNA sequencing approach to profile the lncRNA transcriptome in ZIKV infected Vero cells. We identified a total of 121 lncRNA genes that are differentially regulated at 48 hours post-infection. The majority of these genes are independently validated by reverse-transcription qPCR. A notable observation was that the lncRNAs, MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) and NEAT1 (Nuclear Paraspeckle Assembly Transcript 1), are down-regulated upon Zika viral infection. MALAT1 and NEAT1 are known as nuclear localized RNAs that regulate gene expression and cell proliferation. Protein-lncRNA interaction maps revealed that MALAT1 and NEAT1 share common interacting partners and form a larger network comprising of 71 cellular factors. ZIKV-mediated dysregulation of these two regulatory lncRNAs can alter the expression of respective target genes and associated biological functions, an important one being cell division. In conclusion, this investigation is the first to provide insight into the biological connection of lncRNAs and ZIKV which can be further explored for developing antiviral therapy and understanding fetal developmental processes.

DOI: http://dx.doi.org/10.1101/061788

PUBLISHED: 2016-07-01

Generated MeSH Terms

Humans | Animals | Cercopithecus aethiops | Female | Pregnancy | RNA, Long Noncoding | Adenocarcinoma of lung | Vero Cells | Teratogens | Transcriptome | Sequence Analysis, RNA | RNA, Nuclear | Host-Pathogen Interactions | Microcephaly | Pregnancy Outcome | Zika Virus | Zika Virus Infection | Adenocarcinoma | Lung Neoplasms | Virus Replication | Cell Division | Antiviral Agents | Genotype |

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26085147 | 26283013 | 26527535 | 25889429 | 23835137 | 26071336 | 23324609 | 25885227 | 24148652 | 26363020


When is a bacterial "virulence factor" really virulent?

AUTHORS

Granato, E. T. | Harrison, F. | Kummerli, R. | Ross-Gillespie, A. |

ABSTRACT

Bacterial traits that contribute to disease are termed 'virulence factors' and there is much interest in therapeutic approaches that disrupt such traits. However, ecological theory predicts disease severity to be multifactorial and context dependent, which might complicate our efforts to identify the most generally important virulence factors. Here, we use meta-analysis to quantify disease outcomes associated with one well-studied virulence factor - pyoverdine, an iron-scavenging compound secreted by the opportunistic pathogen Pseudomonas aeruginosa. Consistent with ecological theory, we found that the effect of pyoverdine, albeit frequently contributing to disease, varied considerably across infection models. In many cases its effect was relatively minor, suggesting that pyoverdine is rarely essential for infections. Our work demonstrates the utility of meta-analysis as a tool to quantify variation and overall effects of purported virulence factors across different infection models. This standardised approach will help us to evaluate promising targets for anti-virulence approaches.

DOI: http://dx.doi.org/10.1101/061317

PUBLISHED: 2016-06-29

Generated MeSH Terms

Pseudomonas aeruginosa | Virulence | Virulence Factors | pyoverdin | Iron | Oligopeptides | Iron Compounds | Ecology | Reference Standards |

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26313907 | 23106711 | 22251040 | 22819149 | 24803516 | 25312210 | 26149986 | 19707586 | 21643731 | 19854904


Characterization of Methicillin-resistant Staphylococcus aureus Isolates from Fitness Centers in Memphis Metropolitan Area, USA

AUTHORS

Mukherjee, N. | Sulaiman, I. M. | Banerjee, P. |

ABSTRACT

Indoor skin-contact surfaces of public fitness centers may serve as reservoirs of potential human transmission of methicillin-resistant Staphylococcus aureus (MRSA). We found a high prevalence of multi-drug resistant (MDR)-MRSA of CC59 lineage harboring a variety of extracellular toxin genes from surface swab samples collected from inanimate surfaces of fitness centers in Memphis metropolitan area, USA. Our findings underscore the role of inanimate surfaces as potential sources of transmission of MDR-MRSA strains with considerable genetic diversity.

DOI: http://dx.doi.org/10.1101/061044

PUBLISHED: 2016-06-29

Generated MeSH Terms

Humans | Methicillin-Resistant Staphylococcus aureus | Methicillin | Fitness Centers | Prevalence | Staphylococcal Infections | Staphylococcus aureus | Genetic Variation | Toxins, Biological |

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Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors.

AUTHORS

Emmott, E. | Sorgeloos, F. | Caddy, S. L. | Vashist, S. | Sosnovtsev, S. | Lloyd, R. | Heesom, K. | Goodfellow, I. |

ABSTRACT

Noroviruses produce viral RNAs lacking a 5' cap structure and instead use a virus-encoded VPg protein covalently linked to viral RNA to interact with translation initiation factors and drive viral protein synthesis. Norovirus infection results in the induction of the innate response leading to interferon stimulated gene (ISG) transcription. However the translation of the induced ISG mRNAs is suppressed. Using a novel mass spectrometry approach we demonstrate that diminished host mRNA translation correlates with changes to the composition of the eukaryotic initiation factor complex. The suppression of host ISG translation correlates with the activity of the viral protease (NS6) and the activation of cellular caspases leading to the establishment of an apoptotic environment. These results indicate that noroviruses exploit the differences between viral VPg-dependent and cellular cap-dependent translation in order to diminish the host response to infection.

DOI: http://dx.doi.org/10.1101/060772

PUBLISHED: 2016-06-26

Generated MeSH Terms

RNA, Viral | Norovirus | RNA, Messenger | Interferons | Interferon Inducers | Caspases | Eukaryotic Initiation Factors | Viral Proteins | Peptide Initiation Factors | Mass Spectrometry |

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2017 Ballot

   

National President-Elect:  Vote for ONE
Michael Sadowsky
University of Minnesota
St. Paul, MN
Michele Swanson
University of Michigan Medical School
Ann Arbor, MI
National Secretary: Vote Yes or No
Timothy J. Donohue
University of Wisconsin-Madison
Madison, WI 
Board of Directors (BOD) Early Career Scientist, 1 year term: Vote for ONE
Greetchen Diaz
Puerto Rico Science Technology and Research Trust
San Juan, PR
Jonathan Lenz
University of Wisconsin-Madison
Madison, WI
Board of Directors (BOD) International Scientist, 1 year term: Vote for ONE
Patricio Acosta
CONICET
Buenos Aires, Argentina
Ron Xavier
Ministry for Primary Industries
Wellington, New Zealand
Board of Directors (BOD) At-Large, 2-year term: Vote for TWO
Valerie Harwood
University of South Florida
Tampa, FL
Jennifer Leeds
Novartis Institutes for BioMedical Research
Cambridge, MA
Stanley Maloy
San Diego State University
San Diego, CA
Robin Patel
Mayo Clinic
Rochester, MN
Board of Directors (BOD) At-Large, 3-year term: Vote for TWO     
Wade E. Bell
Virginia Military Institute
Lexington, VA
Karen Carroll
The Johns Hopkins University School of Medicine
Baltimore, MD
Virginia Miller
University of North Carolina, Chapel Hill
Chapel Hill, NC
Steven Specter
University of South Florida Morsani College of Medicine
Tampa, FL
Council on Microbial Sciences (COMS) Early Career Scientist, 1 year term: Vote for ONE
Jeffrey Maloy
University of California, Los Angeles
Los Angeles, CA
Arriana Rieland
Jackson State University
Jackson, MS
 Council on Microbial Sciences (COMS) International Scientists, 1 year term: Vote for TWO
Paul Brown
The University of the West Indies
Kingston, Jamaica
Ziad Daoud
University of Balamand
Beirut, Lebanon
John Hays
Erasmus University Medical Center
Rotterdam, Netherlands

Benno ter Kuile
University of Amsterdam and Netherlands Food
and Consumer Product Safety Authority
Amsterdam, Netherlands

Council on Microbial Sciences (COMS) At-Large, 2-year term: Vote for THREE
Sean Crosson
University of Chicago
Chicago, IL

Jonathan Frye
U.S. Department of Agriculture, Agricultural
Research Service
Athens, GA
Larry McDaniel
University of Mississippi Medical Center
Jackson, MS
Krishna Rao
University of Michigan
Ann Arbor, MI
Thomas Schmidt
University of Michigan
Ann Arbor, MI
Amy Cheng Vollmer
Swarthmore College
Swarthmore, PA
Kristine Wylie
Washington University School of Medicine
St. Louis, MO
 
Council on Microbial Sciences (COMS) At-Large, 3-year term: Vote for FOUR
Aaron Best
Hope College
Holland, MI
David Craft
Penn State Milton S. Hershey Medical
Center and College of Medicine
Hershey, PA
Roberto De Pascalis
U.S. Food and Drug Administration
Silver Spring, MD
Victor DiRita
Michigan State University
East Lansing, MI
Rebecca Ferrell
Metropolitan State University of Denver
Denver, CO
Jonathan Jacobs
MRIGlobal
Kansas City, MO
Elizabeth Marlowe
Roche Molecular Systems Inc.
Pleasanton, CA
Michael Schmidt
Medical University of South Carolina
Charleston, SC

 

sadowskyMichael J. Sadowsky
University of Minnesota
St. Paul, MN

Michael J. Sadowsky, Ph.D., Director, BioTechnology Institute, Distinguished McKnight University Professor, Department of Soil, Water and Climate; and The BioTechnology Institute; University of Minnesota, St. Paul, MN
Education: Dr. Sadowsky studied in the Department of Bacteriology at the University of Wisconsin-Madison and received his B.S. degree in 1977. After obtaining an M.S. degree (1979) in Microbiology/Biology from the University of Wisconsin-Oshkosh, he went on to complete his Ph.D. in Microbiology at the University of Hawaii in 1983, focusing on microbial ecology and molecular biology. Between 1983 and 1985, Dr. Sadowsky did postdoctoral research at McGill University in the plant-microbe interactions group of the Plant Molecular Biology Laboratory.
Professional Experience: He worked briefly for Allied Corporation as a Molecular Biologist and then worked for several years as a Microbiologist for the USDA-ARS in Beltsville Maryland, in the Nitrogen Fixation and Soybean Genetics Laboratory. He joined the faculty at the University of Minnesota in 1989, where he is currently a Distinguished McKnight University Professor in two departments and a member of 10 graduate faculties. Since 2009 he has served as Director of the BioTechnology Institute, a collaboration between the College of Biological Sciences and the College of Science and Engineering established to promote interdisciplinary research and outreach in biotechnology, microbial engineering, microbial processing, and fermentation development. In addition to his teaching and research efforts, Dr. Sadowsky was Director of Graduate Studies for the Microbial Engineering Program and has been Director of Graduate Studies for the Microbial Ecology Minors Program for 25 years.
ASM Activities: Dr. Sadowsky was an editor of the journal Applied and Environmental Microbiology (where he has served on the editorial board since 1986) and is also an editorial board member of the journals Symbiosis, Antonie van Leeuwenhoek, and Microbe & Environments. He previously served as an editor for Molecular-Plant Microbe Interactions and is founding Editor-In-Chief of one of ASMs newest journals – Microbiology Spectrum. He also served on the ASM Branch Organizing Committee and currently serves on the Press Committee.
Publications: He has authored or coauthored more than 285 articles in scientific journals, was elected a fellow of the American Academy of Microbiology in 1999, and a fellow of the American Association for the Advancement of Science in 2008.
Research Interests: Research efforts in his laboratory are directed towards understanding the microbial ecology of host-microbe interactions using new fecal microbiota transplantation (FMT) technology, which his lab helped develop and standardize. He has been using DNA sequencing, metabolomics, and computational methods to provide valuable insights and practical knowledge about how microorganisms in the human GI tract are related to human health at the biochemical level. While his lab has focused on C. difficile associated diarrheal disease, he is also involved in several other projects using FMT, including autism spectrum disorder, ulcerative colitis, and metabolic syndrome.
Dr. Sadowsky’s research efforts are very diverse. He also studies the structure and function of bacteria in soils, water, and in invasive aquatic species using metagenomic approaches. He is also actively involved in developing molecular tools to determine sources of fecal bacteria in the environment and is interested in the identification and characterization of bacterial genes and metabolic pathways involved in the biodegradation of chlorinated herbicides such as atrazine. In addition, his research efforts are directed toward the identification and examination of bacterial genes involved in the early periods of legume-microbe symbioses. He is specifically interested in studying Rhizobium and Bradyrhizobium genes that play a prominent role in saprophytic survival in soils, host/microbe recognition, and the establishment of symbiotic, nitrogen-fixing nodules on several legume plants.

Statement:
I am both honored and humbled to be invited to submit my candidacy for President of the American Society of Microbiology. I am interested in running for ASM president for several reasons, but principally because I believe that I can make a difference in the careers and scientific pursuits of our many diverse members. I bring a broad and varied background in environmental, ecological, and health-related microbiology research. Having worked in industry, government, and academia, I have a full appreciation of careers options in microbiology, a proven ability to obtain research funding from diverse sources, and an ability to communicate my enthusiasm about microbiology to students, members of our community, and legislators. These diverse experiences have taught me how to “pitch” our science to a broad audience and reach-out to students with an excitement for “all things microbiology.”
Over the last 28 years, I have served ASM in several capacities. In addition to serving as an editor of AEM and an editorial board member of this journal for over 20 years, I am currently Editor-in-Chief of Microbiology Spectrum and a member of the ASM Press Committee. I was also Division Q chair and councilor and a two-time member of the Branch Organizing Committee (BOC). I currently serve as liaison to the BOC, in charge of establishing graduate and postdoctoral branches across the US. In all cases, I believe I made a difference and can continue to do so as president.
While this work has been gratifying, I feel I can do even more. Serving as president will allow me to focus on enhancing ASM’s core mission of education, outreach, professional development, certification, capacity building, and diversity. I also look forward to the task of inspiring the next generation of junior scientists through targeted educational programs that tap our best resource – the experience, expertise, and excitement of our dedicated senior members. The excitement must be contagious (no pun intended) to attract the best and brightest students to our field.
Lastly, as Director of the University of Minnesota’s BioTechnology Institute (BTI), I also feel that I have the financial and management background to lead ASM as its direction and priorities evolve. As Director, I have also provided leadership in developing a vision for Microbial Sciences at U of M, including the recent creation of a new Department of Plant and Microbial Biology.

I have a broad vision for the future of ASM, but perhaps foremost is building an appreciation of our work by enhancing communication, both internally among our members, and externally with the public-at-large. I am committed to ASM’s new vision for governance and organizational excellence, to increasing the diversity of our membership, and to strengthening ASM's global partnerships. I believe that our international colleagues are a valued asset and will work with my international collaborators in South America, Asia, and Southeast Asia to further ASM’s global reach.
ASM must be nimble and evolve with the times to take advantage of rapid changes and advancements in science. Part of this effort will require a commitment to enhancing ASM membership, working from the ground up to engender enthusiasm for Microbiology among our students, get them excited to be members of ASM, and involve them as active participants in our societies’ myriad functions and missions. They are our future!

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swansonMichele Swanson
University of Michigan Medical School
Ann Arbor, MI

Michele Swanson, Ph.D., Professor, Department of Microbiology and Immunology, University of Michigan Medical School
Education: After studying biology and playing field hockey and softball at Yale, she was introduced to the exciting world of experimental science as a research technician at Rockefeller University in the lab of Samuel C. Silverstein, an expert in leukocyte cell biology who conducted seminal studies of Legionella pneumophila growth in macrophages. Michele developed a love of genetics as a graduate student, using Saccharomyces cerevisiae as a tool to study gene expression with Marian Carlson at Columbia and Fred Winston at Harvard. After a brief hiatus devoted to her children, she trained as a postdoctoral fellow with Ralph Isberg at Tufts and HHMI, where she developed cell biological methods to analyze the fate of L. pneumophila in macrophages. In addition to exploiting this pathogen as a genetic probe of macrophage function, her lab investigates how metabolic cues govern the microbe’s resilience in the environment and virulence in phagocytes. Currently they are investigating whether changes in the chemistry of Flint, MI’s water supply altered persistence or virulence of L. pneumophila.
Professional Experience: At Michigan, Swanson teaches infectious diseases to medical students, bacterial pathogenesis to graduate students, and current topics in microbiology to freshman undergraduates. She is also Director of the Office of Postdoctoral Studies at the medical school.
ASM Activities: Professor Swanson is an active member of the American Society for Microbiology. In addition to her current roles as Chair of the American Academy of Microbiology, co-host of the podcast This Week in Microbiology, and co-author of the ASM Press textbook Microbe, she has served as Chair of the Microbial Pathogenesis Division B and as a member of the Council Policy Committee, Finance Committee, Colloquium Advisory Committee, General Meeting Program Committee and Meetings Department Strategic Planning Committee. She is a former editor for Molecular Biology and Microbiology Reviews, editorial board member for mBio and Infection and Immunity, and has been a Division B lecturer and Waxman Foundation keynote lecturer. Elsewhere, Swanson served as a Councilor for the Society for Leukocyte Biology and Chair of a 2009 FASEB Summer Research Conference and a 2014 Gordon Research Conference on microbial pathogenesis.
Dr. Swanson is the proud mother of Hannah (Yale ’10, Michigan Law ‘15) and Len (Oregon ’12, Wayne State School of Social Work ‘17).

Statement:
I am honored to be a nominee for President of ASM. Since my eye-opening orientation as a newly-elected member of CPC in 2010, each year of service has deepened my admiration for our Society’s breadth and impact. Inspired by the generous and insightful leadership by many colleagues whose research I’ve long admired, I am compelled to follow their example by contributing my time, energy, values, and experience to strengthen ASM.
ASM is in the midst of radical change. Beyond Microbe 2016, we recently launched new open-access journals, recruited an activist and visionary CEO, and revamped our governance structure. Challenges we must face include disruptive innovations in publishing, clinical microbiology delivery, and careers for microbial scientists, to name a few.
To navigate this dynamic period, I would bring to ASM leadership a commitment to consensus building that is grounded on data-driven reasoning. As a foundation, I would draw from my extensive experience with multiple units within ASM, including: service on Finance (3 yrs), CPC (6 yrs), GMPC (5 yrs), and the Academy Board of Governors (4 yrs, 2 as Chair); interactions with trainees, educators, and Branch members as a Waksman Foundation keynote lecturer (6 Branch Meetings), ABRCMS speaker and poster judge (2 yrs), and ASMCUE focus group leader and speaker (2 yrs); as well as my educational outreach for the general public as a co-host of the podcast “This Week in Microbiology” (3 yrs). In addition, for the past two years I’ve worked closely with ASM Education and ASM Press as we incorporated the 2012 ASM Curriculum Guidelines into the second edition of the undergraduate textbook Microbe. As current Chair of the Academy, I’ve established processes to ensure our membership represents the diversity of people and fields in the microbial sciences and fostered discussions among our Board to identify pressing research topics in the microbial sciences. I’ve also collaborated with Strategic Alliances to build for the first time three Coalitions: groups of experts from academia, industry and government who work to advance practices and policies i) to guide use of next-generation-sequencing in clinical diagnosis, ii) to combat antimicrobial resistance, and iii) to advance microbiome research. I will also bring to the position three years of executive experience as Director of the Office of Postdoctoral Studies at the University of Michigan Medical School.
The theme of my agenda as President would be communication. To ensure our stature as the go-to source for vetted information in the microbial sciences, it is critical that staff and leaders can rapidly connect with the relevant specialists. To recruit, retain, and engage our members, we must leverage current technologies to build a virtual community of trainees, educators, practitioners, and researchers who can readily identify their mutual interests and share their knowledge. To foster a strong sense of community at our annual meeting, ASM needs to design opportunities for like-minded people to gather for informal conversations. To inspire the next generation of microbiologists and to garner strong support from the public and federal agencies, it is critical that we communicate broadly the excitement, success, and promise of today’s microbial sciences.

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donohueTimothy J. Donohue
University of Wisconsin-Madison
Madison, WI

Timothy Donohue, UW Foundation Chairman Fetzer-Bascom Professor of Bacteriology, Director, Great Lakes Bioenergy, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI
Education: 1975 B.S., Life Sciences, Polytechnic Institute of Brooklyn; 1977 M.S., Microbiology, Pennsylvania State University; 1979, Ph.D., Microbiology, Pennsylvania State University (Mentor, Dr. Robert Bernlohr); 1979-1986 Postdoctoral Fellow/NRSA Fellow & Visiting Assistant Professor – Microbiology Department, University of Illinois at Urbana-Champaign (Mentor, Dr. Samuel Kaplan).
Professional Experience: 1986-1991, Assistant Professor of Bacteriology, University of Wisconsin-Madison (UW-Madison); 1991-1996, Associate Professor of Bacteriology, UW-Madison; 1996-Present. Professor of Bacteriology, UW-Madison; 2016-Present UW Foundation Chairman Fetzer-Bascom Professor; 2007-2009, Director, Wisconsin Bioenergy Initiative, UW-Madison; 2007–Present, Principal Investigator and Director, Department of Energy Great Lakes Bioenergy Research Center, UW-Madison; 2011-Present, Steering Committee Member Wisconsin Energy Institute, UW-Madison; 1986-Present, Trainer in UW-Madison Bacteriology and Microbiology Doctoral Programs; 1986-Present, Trainer in UW-Madison Cellular and Molecular Biology Doctoral Program; 1989-Present, Trainer in UW-Madison Genetics Doctoral Program; 1986-Present, Trainer in NIGMS Molecular Biosciences Pre-doctoral Training Program, UW-Madison; 1988-Present, Trainer in NIGMS Biotechnology Training Program, UW-Madison; 1989-Present, Trainer in NIGMS Genetics Training Program, UW-Madison; Member, AAAS, ACS, ASM, FASEB; SACNAS, SGM SIM, Wisconsin Academy of Arts and Sciences.
ASM Activities: 1975-present ASM Member; 1987, 1990, 1992, 2003, 2007, 2009, 2011, 2017 National Meeting Speaker; 1988-1999 and 2001-Present, Editorial Board, Journal of Bacteriology; 1991, Speaker, Symposium on Sources of Funding for the Introduction of Modern Techniques into the Microbiology Laboratory, ASM General Meeting; 1991-1993, ASM Graduate Student Travel Awards Committee; 1993, Speaker, Symposium on Microbiology and the Undergraduate Biology Curriculum, ASM National Meeting; 1995-1996, Chair-Elect-Genetics and Molecular Biology Divisional Group, ASM; 1995-1996 Selection Committee, ASM Carski Teaching Award; Public Communications Committee, ASM; 1996, Speaker, North Central Branch Meeting, ASM; 1996-1999, Chair-ASM Carski Teaching Award; 1998-2000, ASM Councilor-at-Large; 2004, Co-chair, American Academy of Microbiology Colloquium on Systems Microbiology; 2005, co-Chair & Speaker, Systems Microbiology Roundtable, ASM National Meeting; 2007-2010, American Academy of Microbiology, Intel Science Award Committee; 2008, Plenary Speaker, Opening Session, ASM National Meeting, Boston, MA; ASM President-Elect 2013-2014; ASM President 2014-2015; ASM Immediate Past-President 2015-2016; Member ASM Futures Group 2014-2015; ASM Secretary 2016-Present.
Publications: Some 140 peer reviewed publications & reviews available at https://bact.wisc.edu/p_research_profile.php?id=tdonohue&view=pubs
Research Interests: My laboratory analyzes pathways and networks that microbes use to grow, generate biomass, or produce alternative fuels from sunlight or other renewable sources of energy. To dissect this fundamental problem, we are defining how cells partition resources into growth or formation of valuable products. The metabolic pathways, global regulatory networks, and signals that control expression of relevant pathways are being analyzed using mutants, in vitro systems and computational techniques. The long range goals are to predict metabolic and regulatory activities that are critical to bioproduct formation, to improve pathways of agricultural, environmental and medical importance, and to engineer microbial machines with increased capacity to use sunlight, remove toxic compounds, or synthesize valuable products that are currently derived from fossil fuels.

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diazGreetchen Diaz
Puerto Rico Science Technology and Research Trust
San Juan, PR

Greetchen Díaz, Ph.D., Grants Program Director, Puerto Rico Science, Technology, and Research Trust, San Juan, Puerto Rico
Education: Dr. Díaz completed a Bachelor and Master Degrees in Biology, at the University of Puerto Rico, Mayagüez. Then, she earned her PhD in Molecular, Cellular and Developmental Biology at The Ohio State University, where she studied intracellular protein trafficking using yeast as a model system. Her research described a requirement of the Spindle Pole Body (yeast centrosome) for Targeting/Tethering peripheral proteins to the Inner Nuclear Membrane. After earning her PhD, Greetchen started as a postdoctoral researcher at the Center for Virology, University of Nebraska, where she got a NIH T32 Postdoctoral Fellowship to conduct studies in reproduction of Human Papilloma Virus.
Professional Experience: Dr. Greetchen Díaz is the Grants Program Director at the Puerto Rico Science, Technology and Research Trust. Greetchen was responsible for the implementation of the first local grants in Puerto Rico, such as the Science and Technology Research Grants, the Small Research Grants and the Researcher’s Startup Funds. At the Trust, Dr. Díaz also coordinates the outreach and science education initiatives. For more than 9 years, Greetchen is part of the administrative team of "Ciencia Puerto Rico" (CienciaPR), a non-profit organization that promotes science and scientific careers among Puerto Ricans and Hispanics. At CienciaPR, she participates in numerous projects in science communication, science outreach, and science education. She is the founder and coordinator of CienciaPR's "Borinqueña", the bilingual blog for Hispanic and Puerto Rican Women in Science and Technology. She was the coordinator of "Semillas de Triunfo" (Seeds of Succeed), the first STEM Ambassador Program for middle school girls in Puerto Rico.
ASM Activities: Greetchen is recipient of various ASM awards such as the ASM Student Travel Award, Outstanding Student Poster Presentation, the ASM General Meeting Minority Travel Grant, and the Annual Biomedical Research Conference for Minority Students Judge Subsidy Award. Also, Greetchen was an honorable mention of the Robert D. Watkins Graduate Research Fellowship and a Fellow of the ASM Science Teaching Program. In recent years, Greetchen has been actively involved in ASM’s Strategic Planning (Communications Program) and Governance (Special Committee for selection of the new ASM’s CEO). Greetchen is the co-host of “ASM ¡en Vivo!”, the Spanish-only scientific live-streamed section at ASM Microbe. Dr. Díaz is a member of the board of directors of the Puerto Rico Society of Microbiologists (ASM local branch) were she served as secretary, ASM councilor, and is currently the president-elect.
Publications: Díaz-Muñoz, G., Harchar, T., Lai, TP., Shen, KF, and A. K. Hopper. Requirement of the Spindle Pole Body for Targeting/Tethering proteins to the Inner Nuclear Membrane. Nucleus 2014 Jul 3; 5(4); Guerrero-Medina G, Feliú-Mójer M, González-Espada W, Díaz-Muñoz G, López M, et al. (2013) Supporting Diversity in Science through Social Networking. PLoS Biol 11(12): e1001740; Díaz-Muñoz, G., and R. Montalvo-Rodríguez. 2005. Halophilic Black Yeast Hortaea werneckii in the Cabo Rojo Solar Salterns: Its First Record for this Extreme Environment in Puerto Rico. Caribb. J. Sci. 41: 360-365.

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lenzJonathan Lenz
University of Wisconsin-Madison
Madison, WI

Jonathan Lenz, Postdoctoral Fellow, University of Wisconsin-Madison, Madison, WI
Education: Ph.D. Biology & Biomedical Sciences (Molecular Microbiology), Washington University, St. Louis, MO (2012); B.S. Microbiology, with High Honors, Michigan State University, East Lansing, MI (2005).
Professional Experience: Postdoctoral Fellow, University of Wisconsin-Madison; Advisor: Dr. Joseph Dillard (2012-present); Recipient of NRSA F32 Individual Fellowship, NIAID (2015); Recipient of Microbes in Health & Disease Training Grant (T32) slot (2014); UW-Madison Postdoctoral Association, President (2015 – present), Survey Committee Chair (2014-2015); WiSolve Consulting Group Inc., Board of Directors (2015 – present); Postdoctoral Representative to Department Faculty, Medical Microbiology & Immunology (2012 – 2016); UW-Madison Office of Postdoctoral Studies, Steering Committee Member (2014); UW-Madison MMI Administrative Excellence Program – Workshop Co-creator/Organizer (2014). Doctoral Student, Washington University & UNC-Chapel Hill; Advisor: Dr. Virginia Miller (2006-2012); Recipient of Morse/Berg Fellowship, Washington University (2008). Undergraduate Research Assistant, Michigan State University; Advisor: Dr. Cindy Arvidson (2004-2005); Recipient of Gerhardt Award for Outstanding Undergraduate Research in Microbiology (2005); Recipient of Professorial Assistantship Scholarship, MSU Honors College (2001).
ASM Activities: Member since 2005; General Meeting Attendee; Branch Meeting Attendee
Publications: 10, full list available at NCBI My Bibliography
Research Interests: My research career has focused on the study of pathogenic bacteria important to human health and understanding the mechanistic basis of bacteria-host interaction in human and animal model systems, using a combination of genetic, biochemical and cell biological methods. My current research focuses on 1) enzymes involved in the breakdown and recycling of peptidoglycan (PG) by pathogenic Neisseria species, 2) understanding how released PG fragments impact the immune response in primary human tissues, and 3) how outer membrane vesicle (OMV) formation intersects with PG fragment release. N. gonorrhoeae is an obligate human pathogen that utilizes a reduced complement of peptidoglycanases, compared to E. coli, to complete the cell wall turnover required for normal growth. Mutation of even a single PG-targeting amidase is enough to disrupt cell separation, making PG recycling enzymes attractive targets for antimicrobials. As a byproduct of cell wall recycling, N. gonorrhoeae also releases fragments of PG that are detected by the cytoplasmic sensor NOD1, initiating an inflammatory response. PG fragments have been shown to cause damage to the human Fallopian tube epithelium, including the death and sloughing of ciliated cells, which can lead to irreversible tissue damage and infertility. By utilizing a primary human Fallopian tube explant model, I have been able to identify key components of the innate immune response to N. gonorrhoeae and host factors that drive tissue destruction.
In addition to research, I regularly guest lecturer in an undergraduate course on pathogenic bacteriology and mentor undergraduates in independent research projects. I have been continuously active with the UW-Madison Postdoctoral Association, serving two years as President, where I’ve worked with university administration on behalf of postdoctoral scholars and successfully advanced career development programs for postdocs. This service work has included co-founding a non-profit consulting group (WiSolve) to expose STEM graduate students and postdocs to business skills through projects benefitting the Wisconsin technology and life science community.

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acostaPatricio Acosta
CONICET
Buenos Aires, Argentina

Patricio L. Acosta, PhD, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) – Argentina, Facultad de Medicina - Universidad de Buenos Aires - Argentina
Education: Bachelor of Science – Colegio Gdor. Mariano Saavedra. Master of Science in Genetics – Universidad Nacional del Nordeste (UNNE). Doctor in immunopathology – School of Medicine – Universidad de Buenos Aires (UBA).
Professional Experience: Dr. Patricio Acosta is an Assistant Professor at the National Scientific and Technical Research Council, CONICET (Argentina) and at the School of Medicine – Universidad de Buenos Aires. He received his MSc with concentration in genetics from the Universidad Nacional del Nordeste and his doctorate in immunopathology from the Universidad de Buenos Aires with the highest honors (summa cum laude). Following his graduate training, he completed a postdoctoral fellowship training program at Fundacion INFANT under the supervision of Dr. Fernando Polack. During 2010-11 he worked as research fellow in the laboratory of Dr. James Crowe Jr. at Vanderbilt University. Since 2011, he has led the team responsible of the laboratory viral diagnoses for a huge study funded (for the first time in Argentina) by the Melinda & Bill Gates Foundation. His work combines the virological laboratory diagnostics and investigation. He has received among other distinctions, awards from the Universidad Nacional del Nordeste, the Sociedad Argentina de Microbiología, the Entre Ríos government, the Argentine National Educational Ministry, the International Society of Influenza and Respiratory Viruses, the National Scientific and Technical Research Council and the Macrae Foundation. Finally, this year he received the Young Investigator Award 2016 from the Pan-American Society for Clinical Virology. On the other hand, he has been engaged in teaching undergraduate courses at the Universidad Nacional del Nordeste, Universidad de Buenos Aires and has also served as mentor in the “Translational Health Science Internship in Argentina”, a program from Georgetown University (USA). Finally, is appropriate to mention that Dr. Acosta is guest editor of Mediators of Inflammation Journal.
ASM Activities: Since 2013 ASM Science Ambassador, aims to mobilize next generation of scientists to develop innovative approaches to science. Met with different colleagues from Argentina and around the world, including the ASM ambassadors from more than 50 countries. Last 3 years, represented ASM in several meetings and events in Argentina. Last year, was elected one of 8 members of ASM Young Leaders circle, which delineates science ambassadors program. Last year, elected as Latin American Correspondent from Pan-American Society for Clinical Virology. As Latin-American correspondent, represents Latin-American members in the council of the Society.
Publications: In last 5 years, 13 publications with 4 as first author
Research Interests: Dr. Acosta research interests include understanding the pathogenesis of respiratory viruses (RSV, Rhinovirus & Influenza) and the host immune response to viral infection, particularly in low-income pediatric populations. His principal aim is to develop research initiatives that translate laboratory findings into interventions with direct impact on the welfare of children.

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xavierRon Xavier
Ministry for Primary Industries
Wellington, New Zealand

Ron Xavier, Dr, New Zealand Ministry for Primary Industries, Wellington, New Zealand
Education: Doctor of Philosophy, Year obtained: 2014, University of Waikato, Thesis title: Survival of Escherichia coli O157:H7 during starvation at low temperatures; Master of Science (1st Class Honors) in Medical Science, Year obtained: 2006, University of Auckland; Bachelor of Science, Year obtained: 2004, University of Auckland, Major: Biomedical Sciences, Specialization: Microbiology & Immunology
Professional Experience: My experience spans across a number of applied fields, from quality assurance for food products, clinical laboratories, applied research, to public service. I have also taken a number of leadership opportunities to facilitate discussion and foster understanding between different disciplines, cultures and generations. Director of Communications, Asia Pacific Research Institute, 2016-present, Managed the strategic direction of membership management and communications, particularly for the Asia Forum which is aimed to enhance New Zealand’s understanding of the Asia Pacific region; Senior Adviser (Market Access North Asia), New Zealand Ministry for Primary Industries, 2016-present, Provide technical advance and support for the development, maintenance and review of market access and official assurance requirements, including input into market access strategies and stakeholder engagement; Adviser (Market Access Liaison and Cooperation), New Zealand Ministry for Primary Industries, 2015-2016, Supported the implementation of sanitary phytosanitary activities under free trade agreements including facilitation of technical cooperation programs, stakeholder engagement and resource coordination; Millennial Catalyst, International Connector, 2015-present, Part of a unique global think tank to solve problems, provide solutions and new ideas and to kick-start innovative programs. Working both online and offline, the Millennial Catalysts provide a direct source of insight from this critical demographic; Adviser (Food and Beverage), New Zealand Ministry for Primary Industries, 2015-2014, Managed the development, evaluation, review and implementation of legislations for the production and processing of food in New Zealand including provision of technical advice identification of scientific information and stakeholder engagement; Young NZ Asian Leader Member, New Zealand Asian Leader (NZAL), 2014-2016, Participant in the Public Sector Roundtable aimed to improve cultural understanding within the public sector and improve formation and delivery of public policies to the increasing Asian population in New Zealand; Scientist (Food & Bio-based products), AgResearch Ltd, 2012-2014, Provide scientific services to support New Zealand meat and dairy industries including; Medical Laboratory Technician, Waikato District Health Board, 2012, Conduct clinical testing for the molecular biology department; Leadership Network Member, Asia New Zealand Foundation, 2009-current, Foster understanding between New Zealand and Asia through cultural events, business and diplomacy; Laboratory Technician (Chemistry), Fonterra Cooperation, 2007-2008, Product quality assurance testing for dairy products.
ASM Activities: ASM Young Leader Circle (2015-present); ASM Futures Project; ASM Young Ambassador of Science (first cohort, 2013-2016)
Publications: 1 Journal publication; 8 Conference abstracts
Research Interests: Through my experiences, I have developed a keen interest in facilitating discussions and understanding between different disciplines, cultures and generations through effective engagement, communication and strategic direction. My current interest is the application of science in the harmonization of technical standards for the trade of food and other primary products. A key aspect of this interest is the communication and use of science in meeting the consumer needs, business needs, as well as effective government regulatory oversight.

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harwoodValerie Harwood
University of South Florida
Tampa, FL

Valerie J. (Jody) Harwood, Professor and Chair, University of South Florida, Tampa, Florida
Education: BA in French from Iowa State University in 1980; BA in Biology from SUNY; Plattsburgh, 1983; Ph.D. in Biomedical Sciences from Old Dominion University & Eastern Virginia Med School in 1992
Professional Experience: Postdoctoral: University of Maryland Center of Marine Biotechnology 1992-1995; Assistant Professor: University of North Florida Dept. Natural Sciences 1995-1998; Assistant Professor, University of South Florida Department of Biology 1998-2004; Associate Professor, University of South Florida Department of Biology 2004-2010; Professor, University of South Florida Department of Integrative Biology 2010-current; Chair and Professor, USF Department of Integrative Biology 2014-current.
ASM Activities: Member since 1983 (with a brief interruption before starting PhD program in 1987);
President of Southeastern Branch ASM 2005-2006; Editorial Board, Applied & Environmental Microbiology 2006 – current; Councilor, Southeastern Branch 2010-2012; Councilor, Division at Large 2012-2014; Council Policy Committee 2014-2017; Distinguished Lecturer 2014-2016;
Editorial Board, Microbiology Spectrum 2016-Present
Publications: Over 90 total peer-reviewed publications. Fifteen papers have at least 100 citations, with over 4800 total citations, a h-index of 35, and a h-10 index of 75.
Research Interests: The ongoing research area that has defined my career is the question of what happens to gut-associated microorganisms when they enter man-made (e.g. wastewater) or natural aquatic environments. This line of investigation has led to work on differential survival of E. coli strains (Anderson et al., AEM 2005), exploration of the indicator organism paradigm in wastewater treatment (Harwood et al., AEM 2005), and a large body of work on microbial source tracking (MST), which endeavors to determine the source(s) of fecal pollution in water. Recent work has affirmed the importance of protozoan predation on the fate of enteric bacteria in water bodies (e.g. Korakjkic et al., AEM 2013; Wanjugi and Harwood, Microb. Ecol. 2014; Wanjugi et al., Microb. Ecol 2016). The occurrence and fate of antibiotic resistant bacteria is also an ongoing interest, and produced a recent paper on survival of vancomycin-resistant enterococci (VRE) released during a sewage spill (Young et al., AEM 2016). In contrast to the fecal-to-water journey taken by the other microbes I study, Vibrio vulnificus occurs naturally in the water and infects humans quite by chance. Its tendency to become viable but nonculturable (VBNC) during colder months, and its lack of overt virulence factors provide many methodological challenges and intriguing hypotheses. My lab has recently begun to explore the role of epigenetic modifications, e.g. DNA methylation, on gene expression and virulence in this opportunistic estuarine pathogen. Finally, effective preparation and mentoring of the graduate students who are in the research trenches is one of my enduring passions. I am very proud of the success of the 12 Ph.D. and six Master’s students who contributed so much to the work mentioned above.

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leeds
Jennifer Leeds

Novartis Institutes for BioMedical Research
Cambridge, MA

Jennifer A. Leeds, Ph.D., Executive Director, Infectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, CA
Education: B.S. Microbiology, Cornell University, 1991; Ph.D. Medical Microbiology and Immunology, University of Wisconsin-Madison, 1996 (advisor, Rodney Welch); NIH Postdoctoral Fellow, Microbiology and Molecular Genetics, Harvard Medical School 1996-2001 (advisor, Jon Beckwith)
Professional Experience: Novartis Institutes for Biomedical Research 2003-present, Investigator → Executive Director, Infectious Diseases Area; Cambridge MA → Emeryville, CA; DYAX CORP., Cambridge, MA 2001-2003, Senior Scientist, New Technologies; Co-Chair, Gordon Research Conference on New Antibacterial Discovery and Development, 2016; Co-Chair, American Society for Microbiology Conference on Antibacterial Development, 2016; Co-Chair, Keystone Symposium on Antimicrobial Resistance, 2017; Editorial Advisory Board Member: ACS Infectious Diseases; Ad hoc reviewer: PNAS, Nature, J. Bacteriology, Antimicrobial Agents and Chemotherapy, others; Peer reviewer, Wellcome Trust; Reviewer, NIH study section: “Non-Traditional Therapeutics that Limit Antibacterial Resistance”; Executive Board Member - Institute for Drug Resistance (http://drug-resistance.org/) 2012-2014; Cornell Alumni Admissions Ambassador, Cornell University, Ithaca NY; Teaching and Mentoring: Novartis Education Office – “Target to Therapy”; Formal mentor in NIBR LEAD and Greenhouse programs, NIBR Emeryville Mentorship program; Harvard Medical School, TA for Clinical Microbiology (1996-1998); University of Wisconsin Medical School, TA for Clinical Microbiology (1991-1992); Cornell Adult University, course developer and instructor (“Junior Veterinarian”, 1990); University of Rochester Dept. of Microbiology and Immunology, guest instructor (2013); Washington University, Infectious Diseases Gateway Course, guest instructor (2012, ‘13, ’15, ‘17); MIT Advanced Seminar in Microbiology for Undergraduates, guest instructor (2005)
ASM Activities: Member, 1990-present; Co-Chair, American Society for Microbiology Conference on Antibacterial Development, 2016
Publications: 38 publications; 8 leadership publications and presentations; 3 patent applications
Research Interests: Expert in bacterial genetics and physiology, antibacterial mechanisms of action and resistance, clinical microbiology, drug discovery, clinical development; Responsible for strategy and execution of new antibacterial portfolio from target discovery through clinical validation and Clinical Microbiology from discovery through post-approval commitments; Co-inventor, international discovery project team leader, and clinical development core team member for the novel antibacterial LFF571; Expert and key decision-maker in business development strategy and licensing opportunities; Extensive experience in building high-value organizations, developing and retaining top talent, and leading in a matrix environment; Continuously relied upon to enable high impact public and professional engagement by bringing communication and subject matter expertise to a wide range of audiences; Trusted senior leader - advise and execute on highly sensitive, strategic decisions and projects

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maloysStanley Maloy
San Diego State University
San Diego, CA

Maloy, Stanley, Professor of Microbiology, San Diego State University, San Diego, CA
Education: 1981 Ph.D. in Molecular Biology and Biochemistry, University of California, Irvine; 1977 M.S. in Microbiology, California State University, Long Beach; 1975 B.S. in Biological Sciences, University of California, Irvine
Professional Experience: 2006-2010 Chief Scientific Officer, Vaxiion Therapeutics, Inc., Sorrento Valley, CA; 2003-2006 Director, Center for Applied and Experimental Genomics, San Diego State Univ.; 2002-2014 Co-Director, Bacterial Pathogenesis Course, Watson Graduate School, Cold Spring Harbor Laboratory, NY; 2000-2006 Director, Center for Microbial Sciences, San Diego, CA; 2001-2002 Director, Biotechnology Center, Univ. Illinois, Urbana, IL; 1995-2002 Professor of Microbiology, University of Illinois, Urbana, IL; 1991-1992; Sabbatical leave at the California Biological Research Institute La Jolla, CA ; 1990-1995 Associate Professor of Microbiology, Univ. Illinois, Urbana, IL; 1990-1995 Instructor, Advanced Bacterial Genetics Course, Cold Spring Harbor Laboratory, NY; 1984-1990 Assistant Professor of Microbiology, Univ. Illinois, Urbana, IL; 1982-1983 Instructor, Human Genetics, Univ. Utah, Salt Lake City, UT; 1981-1984 Postdoctoral fellow at Univ. Utah, Salt Lake City, UT ; 1979-1980 General Chemistry Instructor, Saddleback College, Mission Viejo, CA; 1977-1981 Teaching assistant for General Microbiology Labs, UC Irvine; 1976-1977 Teaching assistant for Bacterial Physiology Labs, CSU, Long Beach; 1975-1977 Electron Microcopy technician, Microbiology Department, CSU Long Beach; 1975-1976 Teaching assistant for General Microbiology Labs, CSU Long Beach; 1974-1975 Co-Founder, Laboratory Management Co., Torrance, CA (Clinical Laboratories),
ASM Activities (Selected): 2017 Chair, Microcosm Editorial Board; 2016-2019 AAM Basic Sciences Award Selection Committee ; 2015-2016 ASM Awards Committee Chair; 2012-2016 Chair, Microbe Editorial Board; 2012-2015 Selection Committee Abbott-ASM Lifetime Achievement Award; 2009-2012 Selection Committee; Schaechter Award for Distinguished Service in the Developing World ; 2010-2012 General Meeting Organizing Committee; 2010 ASM Latin America Professor, Univ. Nacional Agraria La Molina, Lima, PERU; 2009-2016 Editorial Board, MBio; 2009-2011 ASM Branch Lecturer; 2006-2012 Chair, Communications Committee ; 2005-2007 INTEL International Science Fair, ASM Awards Judge; 2004-2007 ASM President-elect, President, Past-President ; 2001-2004 Council and Policy Committee; 2001-2003 Carski Award Committee ; 2000-2004 Executive Editor, Escherichia coli and Salmonella, ASM Press; 2000-2003 Editorial Board, Infection & Immunity; 1999-2001 Councilor, American Society for Microbiology Division H; 1998-2004 Chair, ASM Press; 1998 Elected Fellow, American Academy of Microbiology ; 1997-1998 Alternate Councilor, American Society for Microbiology Division H; 1990 American Society for Microbiology Latin American Professorship; 1986 American Society for Microbiology Vector Award
Publications: 100+ publications; 9 books
Research Interests: The research in my lab is focused on bacterial and phage genetics, the evolution of infectious diseases and host-specificity, and the development of new vaccines and antimicrobials. Over the course of my career, my research interests have evolved from a “reductionist” focus to a much broader focus that includes a “one health” perspective – that is, to achieve human health requires attention to animal health and environmental health. In addition, I have am a member of an I-Corps team focused on promoting entrepreneurship in biotechnology. Our work has been supported by the NIH, NSF, USDA, W. M. Keck Foundation, and venture capital.

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patelRobin Patel
Mayo Clinic
Rochester, MN

Robin Patel, MD, FRCP(C), D(ABMM), FIDSA, FACP, F(AAM), Chair, Division of Clinical Microbiology; Director, Infectious Diseases Research Laboratory; Co-Director, Clinical Bacteriology Laboratory; Professor of Microbiology and Medicine, Mayo Clinic, Rochester, Minnesota
Education: Princeton University, BA Chemistry, 1985; McGill University, MD, 1989; Mayo Clinic, Internal Medicine Residency, Infectious Diseases and Clinical Microbiology Fellowships, 1989-1996
Professional Experience: 96-Present Faculty, Mayo Clinic (Assistant Professor, 96-00; Associate Professor, 00-06; Professor, 06-Present); 96-Present Member, Infectious Diseases Research Committee, Mayo Clinic; 98-Present Multiple NIH Study Sections and Special Emphasis Panels; 00-09 Chair, Infectious Diseases Research, Mayo Clinic; 01-Present Director, Microbiology Course, Mayo Medical School; 04-06 Member, IDSA Publications Committee; 07-12 Program Director, Clinical Microbiology Fellowship Program, Mayo Clinic; 07-10 Member, Student Promotions Committee, Mayo Medical School; 07-Present Director, Clinical Bacteriology Laboratory, Mayo Clinic (Co-Director 15-Present); 07-Present Basic Science Theme Leader, Mayo Medical School; 09-Present USMLE Committees: Microbiology and Immunology Test Development (Member 09-14; Chair, 14-17), Item Review (Member 15-present); 09-Present Member, Mayo Foundation Conflict of Interest Review Board; 10-15 Member, Research Finance Subcommittee, Mayo Clinic; 10-13 Member, IDSA’s Annual Meeting Planning Committee; 11-Present Chair, Division of Clinical Microbiology, Mayo Clinic; 13-15 Chair, Diagnostics and Devices Subcommittee, Antibacterial Resistance Leadership Group (ARLG); 13-Present Member, Mentoring Committee, ARLG; 13-14 Advisor, Clinical and Laboratory Standards Institute (CLSI), Subcommittee on Antimicrobial Susceptibility Testing; 15-Present Director of Diagnostics and Master Protocol, ARLG; 15-Present Member, CLSI, Subcommittee on Antimicrobial Susceptibility Testing; 16-Present Member, Research Space and Equipment Subcommittee, Mayo Clinic; 16-Present Associate Editor, Clinical Infectious Diseases; 17-20 Member, National Advisory Allergy and Infectious Diseases Council
ASM Activities: 92-Present Member; 99-07 Editorial Board, Journal of Clinical Microbiology; 02-07 ICAAC Program Planning Committee (ICAAC/IDSA Committee 2007); 01-10 Editorial Board, Antimicrobial Agents and Chemotherapy; 02-13 Editorial Board, Clinical Microbiology Reviews; 09-19 Associate Editor, Journal of Clinical Microbiology; 10-13 BD Award for Research in Clinical Microbiology Nominations Committee; 11-18 ASM Microbe Program Planning Committee (Vice Chair 13-15; Co-Chair 16-18); 2012 Fellow - American Academy of Microbiology; 2013 Meetings Strategic Planning; 2014 Communications Strategic Planning; 2014 Bill and Melinda Gates Foundation-ASM Meeting; 2015 ASM BD Award for Research in Clinical Microbiology Recipient; 15-17 Clinical Awards Selection Committee Member; 2016 JCM/ASM China Publications Event
Publications >245 publications http://www.ncbi.nlm.nih.gov/sites/myncbi/robin.patel.2/bibliograpahy/47618838/public/?sort=date&direction=ascending
Research Interests: My research focuses on microbial biofilms, antimicrobial resistance and clinical bacteriology diagnostic testing. I have a longstanding interest in novel strategies for detection and management, and understanding the pathogenesis of, biofilm-associated orthopedic infection, especially prosthetic joint infection (PJI). I have developed a number of diagnostic assays for PJI and have an active research program investigating novel PJI treatment and diagnostic strategies. My group also works on antibacterial resistance, performing phenotypic and genotypic studies of resistance in Gram-positive and Gram-negative bacteria. We have described new types of resistance. In addition, I have a longstanding interest in animal models of infection, as means for evaluating novel antimicrobial agents and for studying the pathogenesis of infections. Many of the models we use were developed in my laboratory. Finally, I have a track record of developing novel diagnostic assays for clinical practice.

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bellWade E. Bell
Virginia Military Institute
Lexington, VA

Wade E. Bell, Ph.D., Professor of Biology, Virginia Military Institute, Lexington, Virginia
Education: Ph.D. University of Vermont, Cell and Molecular Biology, 1999; M.Ag. University of Florida, Entomology and Nematology, 1984; B.S. University of Florida, Entomology and Nematology 1981
Professional Experience: I began my career as an ecologist, studying nematode parasites of mosquitos. I subsequently left science for a 6-year stint in the United States Air Force. After separation, I worked 4 years in an immunology/virology laboratory studying influenza pathogenesis and host defense. I moved to the University of Vermont in 1994 to do Ph.D. work in a neuroscience laboratory which used the eukaryotic microbe Paramecium as a model organism. I secured a faculty position at the Virginia Military Institute (a small liberal arts and engineering college) in 1998 and have moved up the ranks to full Professor. I spend significant time teaching and mentoring students in the classroom and research lab. I am also currently the Director of VMI’s sponsored programs and grants corporation. I have been involved in grant programs management for 18 years. I also have served as our institutional Health Professions advisor for the past 19 years. In this capacity, I was elected to serve on the Board of Directors of the National Association of Advisors for the Health Professions. I have also served on the Board of Directors of my local SPCA.
ASM Activities: My involvement with ASM began 18 years ago. I learned that the ASM Virginia Branch meeting was a good place for undergraduates to present research. After several meetings, I became involved in Branch leadership, being elected to serve as Branch Councilor. I served 2 different 4 year terms on ASM Council. In between I served as the Virginia Branch President. For the last 4 years I have served as a Branch representative to the Council Policy Committee. During this period, I was heavily involved with development of the new ASM governance structure just passed by the membership. Perhaps my most rewarding ASM leadership experience has been serving on the Membership Board as the Chair of the Student Membership Committee for the past 8 years. Supporting student chapter programing and running orientations and student developmental programming at the General Meeting has allowed me to personally interact with thousands of early career members. I have also had the honor of being a founding member of Division AA, our Protist division.
Publications: 8 publications
Research Interests: My research interests currently focus on mitochondrial contributions to cell development and behavior in Paramecium and other Protists. I am driven to ask questions about the evolution of the symbiotic relationship between mitochondria and their cellular hosts. As a microscopist, I have also been involved in many collaborations with different laboratories, as reflected by my publication history.

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carrollKaren Carroll
The Johns Hopkins University School of Medicine
Baltimore, MD

Karen C Carroll, MD, Professor of Pathology, Director, Division of Medical Microbiology, Section Director Bacteriology and Molecular Epidemiology, The Johns Hopkins University School of Medicine, Baltimore, MD
Education: 1975 B.A., Biology, College of Notre Dame, Baltimore, MD; 1979 M.D., University of Maryland School of Medicine; 1978-80 Internship in Medicine, University of Maryland; 1980-82 Residency in Primary Care Internal Medicine (R2 & R3), Associated Hospitals Program in Internal Medicine, University of Rochester; 1982-83 Chief Residency, Associated Hospitals Program in Internal Medicine, University of Rochester; 1984-86 Fellow in Infectious Diseases, University of Massachusetts Medical School, Worcester, MA; 1989-90 AAM/CPEP Fellow in Medical Microbiology, Department of Pathology, University of Utah Health Sciences Center; 2011-2013 Science of Clinical Investigation Certificate Program, Johns Hopkins Bloomberg School of Public Health; 2012-2013 Leadership Program for Women Faculty
Professional Experience: 1982-83 Instructor in Medicine, University of Rochester; 1983-84 Staff Physician, Mattapan Chronic Disease Hospital, Boston, MA; 1985-86 Instructor in Medicine, University of Massachusetts Medical Center; 1986-88 Hospital Epidemiologist, St. Joseph's Hospital, Memphis, TN; 1988-90 Clinical Instructor in Medicine, University of Utah Medical Center; 1990-91 Limited Term Instructor, Department of Pathology, University of Utah; 1991-1997 Assistant Professor of Pathology, University of Utah; 1991-1997 Adjunct Assistant Professor of Infectious Diseases, University of Utah; 1997 Associate Professor of Pathology, University of Utah, Award of Tenure; 1997 Adjunct Associate Professor, Infectious Diseases, University of Utah; 2002 Associate Professor Pathology and Medicine, Johns Hopkins University School of Medicine; 2002-2015 Secondary Appointment Division of Infectious Diseases, Johns Hopkins University School of Medicine; 2006-present Professor Pathology, Johns Hopkins University School of Medicine
ASM Activities: Editorial Activities: Journal of Clinical Microbiology—Editorial Board, 2001—present; Editor, 2010-present; Manual of Clinical Microbiology volume editor, chapter author for 10th and 11th editions; Co-Editor in Chief for 12th edition; Co-editor of first edition of new book entitled “Diagnostic Microbiology of the Immunocompromised Host”. Hayden RT, Carroll KC, Tang YW, Wolk DM, eds. ASM Press, Washington DC, 2009. Co-editor, Diagnostic Microbiology of the Immunocompromised Host, 2nd ed. Hayden RT, Carroll KC, Tang YW, Wolk DM, eds. ASM Press, 2016. Committees: September 1999 American Academy of Microbiology Steering Committee for Colloquium Planning; July 2003-June 2009 Appointment to Advisory Board of American College of Microbiology; July 2003-June 2009 American College of Microbiology Liaison to ASM Professional Development Committee; June 2004 Chairman of Ad Hoc Committee on Board Examination Fees for Advisory Board of American College of Microbiology; July 2005 Elected alternate to Committee on Election to Fellowship, American Academy of Microbiology; 2009-2012 ASM bioMerieux Sonnenwirth Award Nominations Committee; 2010-2013 ASM Mentorship Task Force; 2011-2015 ASM ICAAC Program Committee; 2015-2016 ASM Microbe Program Planning Committees; July 2015 ASM Division C Chair Elect; July 2016 ASM Division C Chair; Oct 17-18, 2016 American Academy of Microbiology Colloquium “"Changing Diagnostic Paradigms for Microbiology”—served as steering committee member and participant
Publications: Published 235 peer-reviewed scientific papers, 38 invited reviews or guidelines, and 50 book chapters
Research Interests: Focused research interests include diagnosis and epidemiology of healthcare associated infections including MRSA, VRE and Clostridium difficile. In addition, Dr. Carroll has participated in and published results of numerous trials on performance and impact of broad variety of rapid diagnostic platforms. She received prestigious ASM BD-Research award in 2011.

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millerVirginia Miller
University of North Carolina, Chapel Hill
Chapel Hill, NC

Virginia L. Miller, Professor of Genetics and Microbiology & Immunology, University of North Carolina at Chapel Hill, North Carolina
Education: Dr. Miller earned her B.A. at the University of California at Santa Barbara, and a Ph.D. in Microbiology and Molecular Genetics from Harvard University where she studied regulation of cholera toxin expression. She then pursued postdoctoral training at Stanford University where she began her studies on Yersinia and Salmonella.
Professional Experience: After postdoctoral training at Stanford University, she joined the faculty at UCLA where she was granted tenure in 1994. She then moved to Washington University in St. Louis in 1996 and in 2008 she moved to the University of North Carolina at Chapel Hill as Professor and Associate Dean of Graduate Education in the School of Medicine.
ASM Activities: Dr. Miller has served as Chair and Chair-elect of Division B for ASM, Councilor at Large, and as Divisional Group II Representative. She has served on the ASM Conferences Committee, as Vice-Chair and Co-Chair of the ASM Biodefense Research Meeting and on the General Meeting Planning Committee. She also has served on the Editorial Boards of Infection & Immunity and Journal of Bacteriology. She previously served as Chair of the Distinguished Service Award Selection Committee, and currently serves on the Committee on Elections (Chair in 2016) for the American Academy of Microbiology.
Publications: She has published 95 peer-review original research articles and nineteen peer-reviewed review articles. Link to publications: http://www.ncbi.nlm.nih.gov/sites/myncbi/1XGFf6MOQJdkg/bibliography/41470052/public/?sort=date&direction=ascending
Research Interests: She began her studies on the molecular analysis of Yersinia enterocolitica-host interactions as a postdoctoral fellow and has continued those interests in her own laboratory. The overall goals of her research are to understand the bacteria-host interaction at the molecular level to learn how this interaction affects the pathogenesis of infections. She also has a long-term interest in understanding how pathogens co-ordinate the expression of virulence determinants during an infection. To do this her laboratory uses genetic, molecular and immunological approaches in conjunction with mouse models of infection. Currently her lab is focusing on studies of Yersinia pestis and Klebsiella pneumoniae.

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specterSteven Specter
University of South Florida Morsani College of Medicine
Tampa, FL

Steven Specter, Professor of Molecular Medicine & Associate Dean for Alumni Relations, University of South Florida, Morsani College of Medicine, Tampa, FL
Education: 1969 BA in Biology Temple University, Philadelphia, PA; 1975 Ph.D. Microbiology and Immunology, Temple University; 1974-1976 Post-doctoral Fellowship, Viral immunodeficiency, Albert Einstein Medical Center, Philadelphia, PA
Professional Experience: 1976-1979 Assistant Director Clinical Microbiology, Albert Einstein Medical Center, Philadelphia, PA; 1979-Present Faculty, Department of Molecular Medicine, University of South Florida Morsani College of Medicine, Tampa, FL; 1979-1984 Assistant Professor; 1984-1991 Associate Professor; 1991- Present Professor; 1997-2001 Associate Dean for Curriculum and Medical Education; 2001-2014 Associate Dean for Student Affairs; 2014-Present Associate Dean for Alumni Relations and Advancement
ASM Activities: 1972-Present Member, ASM; 1977-1979 Newsletter Editor, Eastern Pennsylvania Branch ASM; 1981-1986 Editorial Board, J. Clin. Micro.; 1983-1986 Editorial Board, Cumitech; 1984-2003 Secretary (84-89), President-Elect (97-99), Chair (99-01), Councilor (90-92, 01-03), Florida Branch ASM Chair-Elect, Chair – ASM division V; 1985 Professorship, Latin American Professorial Program, Quito, Ecuador; International Committee/International Board; 1986-1996 Editor-in-Chief, Cumitech & Member, Publications Board; 1993-1995 Chair-elect (93-94), Chair (94-95), Clinical and Diagnostic Immunology Division (V); 1996-2006 Editorial Board - Clinical and Diagnostic Laboratory Immunology; 2002-2007 Editor, Clinical Microbiology Reviews; 2001-Present Member, International Committee/International Board; 2001- 2004 Member, International Microbiology Education Committee; 2005-2014 Chair, Laboratory Capacity Building Program; 2014-2017 Chair, International Board; 2014-Present Chair, Clinical Virology Symposium; Also, Reviewer, Infection and Immunity, J. Clin. Micro, J. Virology, Clin. Micro. Reviews
Publications:Greater than 175 Publications mostly in the areas of retrovirus induced immunodeficiency and effects of recreational drugs on immunity; 12 Books edited; Numerous book chapters; Numerous abstracts
Research Interests: Retrovirus induced immunodeficiency & Effects of marijuana on immune function
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maloyjJeffrey Maloy
University of California, Los Angeles
Los Angeles, CA

Maloy, Jeffrey, Microbiology PhD Candidate, University of California, Los Angeles
Education: 2017 Ph.D. in Microbiology, Immunology, and Molecular Genetics (anticipated), University of California, Los Angeles; 2011 B.S. in Molecular Biology, University of California, San Diego
Professional Experience: 2016-2017 Teaching Assistant Consultant, University of California, Los Angeles - Organized workshops and two UCLA courses to train new TAs and familiarize them with active learning techniques; 2017 Invited Panelist for “Building Inclusive Classrooms Forum,” University of California, Los Angeles; 2016-2017 Staff Writer, Signal to Noise Magazine; 2016-2017 Vice President, SciComm Hub @ UCLA; 2014-2015 Guest Lecturer for Introduction to Microbial Pathogenesis course, University of California, Los Angeles; 2013-2014 TA for Introduction to Microbial Pathogenesis course, University of California, Los Angeles; 2014 STEAM Carnival outreach facilitator, 2014 Student Mentor, CityLab at UCLA; 2011-2012 Academic Tutor for Advancing Careers in Engineering and Science (ACES) - Taught science to middle school students from low academic performance index schools in the Los Angeles area
ASM Activities: 2015-2016 Contributing Author, Microbe magazine; 2016 Poster presentation at ASM Microbe Conference; 2014 Poster presentation at ASM General Meeting
Publications: Maloy, Jeffrey P. "Different Strokes: Blending Microbiology and Art." Microbe Magazine 11.12 (2016): 421-26. Print. Maloy, Jeffrey P. "I, Cannibal: The Critical Role of Autophagy In Human Physiology." Signal to Noise. 4 Oct. 2016. Web. Maloy, Jeffrey P. "Zombie Genes: New Evidence Points to Genetic Life After Death." Signal to Noise. 27 June 2016. Web. Maloy, Jeffrey P. “Bacterial Infection During Pregnancy May Lead to Neurodevelopmental Disorders.” Signal to Noise. 10 March 2016. Web. Maloy, Jeffrey P. “Gut Bacteria Play a Role in Recovery from Malnutrition.” Signal to Noise. 7 March 2016. Web. Maloy, Jeffrey P. “Hard to Swallow: Outbreaks at Chipotle Restaurants Mimic Broader Patterns of Foodborne Illness in the United States.” Signal to Noise. 4 March 2016. Web. Erickson, Stacy L., Elizabeth O. Corpuz, Jeffrey P. Maloy, Christy Fillman, Kristofer Webb, Eric J. Bennett, and Jens Lykke-Andersen. "Competition between Decapping Complex Formation and Ubiquitin-Mediated Proteasomal Degradation Controls Human Dcp2 Decapping Activity." Molecular and Cellular Biology 35.12 (2015): 2144-153. Web.
Research Interests: My research is focused on the mechanisms of cell-cell spread in Burkholderia pseudomallei. Specifically, I study a recently discovered mechanism of intracellular motility mediated by an alternative Burkholderia flagellar system in human tissue culture. The use of flagella for intracellular motility by Burkholderia has profound implications for the innate immune response to infection, and I am currently evaluating the effect of this motility system on the intracellular life cycle and host response to Burkholderia infection.

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rieland 1Arriana Rieland
Jackson State University
Jackson, MS

Arriana Rieland, Undergraduate student, Jackson State University, Jackson, MS
Education: B.S. in Biology; Minor in Chemistry
Professional Experience: From January 2016 to April 2016, I was a lab assistant to Dr. Pacurari at Jackson State University. I helped study the proliferative effects of different chemotherapy treatments on lung cancer cells. Around that same time until December 2016, I also became a member of the Expeditions in Training, Research, and Education for Mathematics and Statistics through Quantitative Explorations of Data (EXTREEMS-QED) program on campus. My mentor was Dr. Jun Liu and we studied mathematical oncology. Our focus was to optimize growth models and chemotherapy treatments by coding through the program Octave. During the summer of 2016, I was invited to participate in the National Institute of Diabetes and Digestive and Kidney Diseases Short-Term Research Experience for Underrepresented Persons Program (NIDDK STEP-UP). I did my research at the University of California San Francisco under the guidance of Dr. Diego Miranda. Our interest was on Non-Alcoholic Fatty Liver Disease and more specifically, our project focused on the implementation of CRISPR/Cas9 in mouse liver and primary hepatocytes. In addition to research experience, I’ve been a tutor and a mentor to students at my university. Starting in the spring of 2014 until December of 2016, I became a peer writing tutor at the Richard Wright Center on campus. My duties consisted of meeting with students and helping them with brainstorming, grammar, and sentence formatting. This past fall semester, I also became a mentor in a program called Experienced Mentors Bettering Emerging Researchers (EMBER). The objective of this program was to provide freshman science majors the tools necessary to be successful within their major. This included meeting on a weekly basis to focus on resume building, personal statement construction, grad school prep, and internship applications.
ASM Activities: During November of 2016, I was able to attend my first Annual Biomedical Research Conference for Minority Students (ABRCMS). It was at ABRCMS that I learned about the American Society of Microbiology (ASM) and its pivotal role in science. After ABRCMS, I decided to become a member of ASM and to further pursue the governance board.
Publications: In the summer of 2016, I was awarded the opportunity to conduct research through the NIDDK STEP-UP Program. After the culmination of the program, I presented an oral presentation and a poster presentation at the National Institutes of Health. In October of 2016, I presented my research once again at the National Institute for Mathematical and Biological Synthesis (NIMBioS) conference which was held at the University of Tennessee.
Research Interests: As an aspiring student who wants to attend medical school, my interests are biomedical related. For example, I have interests in chemotherapy treatments, virology, and immunology. However, I am not opposed to learning new topics and I would enjoy researching outside of the biomedical field.

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brownPaul Brown
The University of the West Indies
Kingston, Jamaica

Paul D Brown, PhD, Senior Lecturer and Head, Department of Basic Medical Sciences, The University of the West Indies (The UWI), Mona, Kingston 7, Jamaica
Education: BSc (Hons) with double major in Biochemistry & Chemistry. The UWI, Mona, Jamaica 1989; MPhil in Biochemistry. The UWI, Mona, Jamaica. 1992; PhD in Microbiology (advisor, Paul N. Levett, PhD). The UWI, Cave Hill, Barbados. 1995
Professional Experience: 1999–2001, Assistant Professor, Department of Biology, Chemistry and Medical Technology, Northern Caribbean University, Mandeville, Jamaica; 2001–2009, Lecturer in Microbiology, Department of Basic Medical Sciences, Biochemistry Section, The UWI, Mona, Jamaica; 2003-present, Graduate Course Coordinator, BAMS6011/BC60B: Understanding Research; 2003-2009, Chair, Staff/Student Liaison Committee, Biochemistry section, The UWI, Mona, Jamaica; 2009-present, Senior Lecturer, Department of Basic Medical Sciences, Biochemistry Section, The UWI, Mona, Jamaica; 2012-present, Council member, International Society of Infectious Diseases; 2013-present, Member, FMS Sub-Committee for Research, UWI, Mona; 2014-present, Chair, Faculty of Medical Sciences (FMS) Annual Research Conference and Workshop Organizing Committee, The UWI, Mona, Jamaica; 2014-present, Member, FMS Committee for Annual Research Awards; 2015-present, President, West Indies Group of University Teachers (WIGUT) Jamaica; 2015-present, Member, Health Services Committee, UWI, Mona August 2016-present, Head, Department of Basic Medical Sciences, The UWI, Mona, Jamaica; August 2016-present, Deputy Dean, Allied Health, Faculty of Medical Sciences, The UWI, Mona, Jamaica.
ASM Activities: 2004-present, ASM member; 2008-2010, Country Liaison for Jamaica; 2010-2012, ASM Ambassador for Central America and Caribbean Basin; 2011, Recognized for outstanding service to the International Board; 2012-present, ASM Ambassador to Jamaica; April/May 2014, ASM Ambassador Task Force (Developed white paper outlining the structure and role of an Ambassador Leadership Circle, whose function was to provide strategic direction/stewardship for the Ambassador Program; to allow the International Board (IB) to effectively leverage the Ambassador network to support related initiatives; and to facilitate international volunteers to serve on other ASM leadership bodies); 2014-2016, Appointed member and Chair of inaugural Ambassador Leadership Circle (Provided leadership and oversight of ASM’s strategic direction in terms of communication between members and Ambassadors, international grants and fellowships, and Ambassador Orientation); 2014-2015, Chair, Evaluation Committee for Country Ambassadors (Oversaw the review and appointment of 25 new Ambassadors in October 2014 and 33 new Ambassadors, incl. an Ambassador Council to India in November 2015; 2014-2015, Member, Membership Board Task Force, which was established to review the tiered membership system; 2014-2015, Member of the review committee for the Makela Cassell Travel Award sponsored by FEMS; 2015-2016, Member, International Board.
Publications: 51 peer-reviewed publications, review articles or book chapters.
Research Interests: My laboratory has been involved in two main aspects of research: Molecular mechanisms of Leptospira pathogenesis, and antibiotic resistance gene regulation in bacterial of public health interest. There is a reported 27/100,000 incidence rate for leptospirosis in Jamaica, where two endemic Leptospira strains are responsible for most of the human seroconversions. Current research underway involves identification and characterization of Leptospira virulence-associated genes that are regulated by environmental parameters in challenging the hypothesis that expression of virulence in Leptospirainterrogans Portlandvere is more responsive to changes in temperature, oxidative stress and iron limitation than for Leptospira borgpetersenii Jules. The antibiotic resistance patterns and mechanisms of pathogenicity are being investigated in clinical isolates of Pseudomonas aeruginosa, Staphylococcus aureus (including MRSA), uropathogenic E. coli (UPEC) and Klebsiella pneumoniae. Our efforts have yielded fruit in terms of confirming the role of DNA adenine methylase in the epigenetic regulation of quinolone resistance and P fimbriae expression in UPEC, and virulence attenuation in Staphylococcusaureus using short RNAs using a Caenorhabditis elegans model. Currently, we are investigating the role of the stringent response in stress tolerance and antimicrobial resistance in K. pneumoniae and its contribution to in vivo pathogenesis.

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daoudZiad Daoud
University of Balamand
Beirut, Lebanon

Ziad Daoud, Professor, Clinical Microbiology, Faculty of Medicine, University of Balamand, CHN and KMC hospitals, Beirut, Lebanon
Education: Fellow in Antimicrobial Stewardship- Tufts Medical Center, Tufts University, Boston- USA (Fulbright Scholarship for Research in Medical Sciences 2012); Ph.D. Microbiology- Complutense University of Madrid and the Institut Pasteur, France; Doctor of Pharmacy, honorary degree- Complutense University of Madrid; MSc/BSc Medical Laboratory Sciences- Lebanese University, Faculty of Public Health
Professional experience: Professor, Faculty of Medicine and Medical Sciences- University of Balamand (2010 - to date. (promoted from Associate to full Professor in May 2012); Consultant, Clinical Microbiology, Tufts Medical Center- Tufts University, School of Medicine, 800 Washington St, Boston MA 02111, USA (2012 to 2014.); Head of Clinical Microbiology laboratory KMC in association with AUBMC. 2016 to date; Head of Clinical Microbiology laboratory and Antimicrobial Steward. CHN hospital, Lebanon. 2011 to date; Associate Professor of Microbiology and Director of the Medical Laboratory Sciences Program. Faculty of Health Sciences- University of Balamand. 2005 to 2010; Head of Clinical Microbiology Laboratory. Saint George Hospital- UMC Beirut, Lebanon. 2000 to 2010; Assistant Professor and Director of the Health Promotion Program. University of Balamand. 2000 to 2005; Clinical Microbiology consultant and Chairman of Infection control Department. DBH Governmental University Hospital- Beirut, Lebanon. 2002 to 2008; Coordinator of students’ activities- Faculty of Health Sciences- University of Balamand. Fall 1999 to 2005
ASM activities: Trainer in the ASM workshop organized by the ASM as part of the pre-conference workshops of the LSIDCM (Lebanese Society for Infectious Diseases and Clinical Microbiology) - March 1-3, 2017; Online Mentor for the American Society for Microbiology Minority Mentoring Program for 6 consecutive years 2006- 2010; Participated and presented Posters, e-posters, and abstracts in all ICAAC conferences since 2009; Trainer in the “ASM workshop on scientific writing and publishing” organized by the American Society for Microbiology (ASM)- Beirut April 21, 2015, Monroe hotel, Beirut, Lebanon; Organizer and trainer in the workshop “WHONET in the Medical Laboratory Practice” organized by ASM in collaboration with APUA Beirut September 26 to 30, 2014; Trainer in 2 “WHONET workshop for PULSENET/AMR laboratory network on Foodborne diseases” organized by the Ministry of Public Health (Lebanon), WHO, and the American Society for Microbiology (ASM) in Beirut September 27, 2014, WHO conference room, Beirut, Lebanon; Trainer in the “Standardization of antimicrobial susceptibility course” organized by the American Society for Microbiology (ASM) in Beirut December 14, 2013, WHO conference room, Beirut, Lebanon. Phenotypic detection of bacterial resistance to antimicrobial agents in the Clinical Microbiology Laboratory.
Publications: Around 65 publications in international peer reviewed journals with an average impact factor of 4.2 and an h index of 15 as calculated by researchgate. With more than 750 citations and RG score of 31. For more details: (https://www.researchgate.net/profile/Ziad_Daoud)
Research interest: My current research interest is focused on two areas: 1) Studying the composition of the human gut flora and the identification of new microbial genera and species using the culturomics techniques. In parallel to understanding the relationship between gut and respiratory microbiome and specific human diseases. 2) Studying the phenotypic and genotypic bacterial resistance in the One Health Context, from animals, to environment, to humans. In addition to epidemiological studies aiming at controlling the spread of antimicrobial resistance in the hospital and community

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haysJohn Hays
Erasmus University Medical Center
Rotterdam, Netherlands

John P. Hays, Erasmus University Medical Center Rotterdam (Erasmus MC), Rotterdam, Zuid Holland, the Netherlands
Education: PhD 'The Genetic Diversity and Complement Resistance Phenotype of Moraxella catarrhalis’. Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands. 2000 - 2005. PhD - 'The Molecular Epidemiology of Human Coronavirus 229E'. University of Leicester, Leicester, UK. 1993–1996. MSc (with Distinction) - Biomedical Science. Nottingham Polytechnic, Nottingham, UK 1990–1992. BSc - Biology with Food Science and Nutrition. Oxford Polytechnic, Oxford, UK1983–1986.
Professional Experience: Scientific Research and Management Experience: Coordinator on 3 European Union Funded International research projects - 1) 'Development of Tailored Antimicrobial Treatment Regimens' (www.tailored-treatment.eu). 2) 'New Anti-Bacterials with Inhibitory Activity on Aminoacyl-tRNA Synthetases.' (www.nabarsi.eu). 3) 'An Integrated Tool-Kit.' (www.tempotest-qc.eu). Principle Investigator on 5 European Union Funded International Research Projects - 1) 'Antimicrobial Resistance Rapid Diagnostic Tests Working Group' (JPIAMR). 2) 'Chair / Bedside Diagnosis for Personalized Monitoring and Treatment' (www.diagoras.eu). 3) 'Nanotherapeutics to Treat Antibiotic Resistant Gram-Negative Pneumonia Infections’ (www.pneumonp.eu). 4). 'Novel Prevention and Treatment Possibilities for Otitis Media' (OMVac). 5) ‘Mobile Genetic Elements in the Spread of Antimicrobial Drug Resistance (DRESP2). Scientific Employment: Clinical Scientist Grade B15, Enteric and Respiratory Virus Laboratory, CPHL, London, UK. 1998–1999. Higher Scientific Officer, Virology and Molecular Methods Group, Central Science Laboratory, York, UK. 1997-1998. Medical Laboratory Scientific Officer, Clinical Microbiological Diagnostic Laboratory, QMC Hospital, Nottingham, UK. 1987-1993. Teaching and Training Experience: BSc - 'Clinical Medicine', 'Clinical Technology' and 'Life Sciences', MSc - 'Infection and Immunity', 6 PhD students. Miscellaneous: 1) Scientific Advisor to a Member of the European Parliament. 2) Scientific Board - Omnigen BV (http://www.omnigen.nl/en/about-omnigen-2/). 3) Scientific Advisor - Sparks and Co. (http://sparksandco.com/about-us/team/).
ASM Activities: I am a recent (2 years) member of ASM, but have 8 years of experience as a member of the European Society for Clinical Microbiology and Infectious Diseases and 13 years of experience in the Dutch Society for Microbiology.
Publications: 60 Publications in Scientific Journals e.g. 1) Current problems associated with microbiological point-of-care (POC) testing of respiratory tract infections in primary care. Future Microbiology. 2016. doi 10.2217/fmb-2015-0020. 2) Evaluation of the characteristics of leucyl-tRNA synthetase (LeuRS) inhibitor AN3365 in combination with different antibiotic classes. Eur. J.Clin.Microbiol. Infect.Dis. (2016). doi:10.1007/s10096-016-2738-1. 3) Micelle PCR reduces chimera formation in 16S rRNA profiling of complex microbial DNA mixtures. Sci Rep. 2015. DOI: 10.1038/srep14181. 6x Book Chapters e.g., “The Genus Moraxella.”. In “The Prokaryotes” 2005. Dworkin et al. (Eds.) ISBN: 978-0-387-25496-8. 2x Authorships of Books 1) Principles and Technical Aspects of PCR Amplification. 2008. ISBN 978-4020-6240-7. 2) Experimental Approaches For Assessing Genetic Diversity Among Microbial Pathogens. 2003. ISBN 90-9016462-6. 1x Book Editor New Technologies in Medical Microbiology and Diagnosis. 2012. eISBN: 978-1-60805-316-2.
Research Interests: My research interests have been varied, ranging from the pathogenesis of (bacterial and viral) respiratory tract pathogens to antibiotic resistance and molecular microbiological diagnostics. Though, I have not followed the path of a 'typical' scientist by following a single microbiological research path during my career, my broad experience is allowing me to generate new synergies between my research interests and (for example) colleagues in the fields of bioinformatics and microbiota research.

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terkuileBenno ter Kuile
University of Amsterdam and Netherlands Food and Consumer Product Safety Authority
Amsterdam, Netherlands

Benno H. ter Kuile, Netherlands Food and Consumer Product Safety Authority, Utrecht, The Netherlands, and University of Amsterdam, Amsterdam, The Netherlands
Education: Ph.D. (1989): Hebrew University of Jerusalem, Israel; Marine Microbiology Sc. (Biology; 1981) and M. Sc. (Microbial Ecology; 1983): University of Groningen, The Netherlands
Professional Experience: 2007-present: Full professor (adjunct) University of Amsterdam; special chair on Microbial Food Safety and Antibiotic Resistance in the Food Chain.
2001-present: Senior Scientist, Department of Risk Assessment and Research Coordination, Netherlands Food and Consumer Product Safety Authority
1999-2001: Research associate, Department of Chemistry, University of Leiden, The Netherlands
1992-1999: Research associate and assistant professor, The Rockefeller University of New York, New York, NY.
1989-1992: Post-doctoral Fellow, Institute of Cellular and Molecular Pathology, Université Catholique Louvain, Brussels, Belgium.
ASM Activities: Member since 1991; Session Convener, General Meeting 1997 and 1999; Member of Division K 1991- 2001 and Division P, 2001-present
Publications: Approximately 60 articles as first or lead author, many of these in ASM journals
Research Interests: Development and mechanisms of antimicrobial resistance and microbial food safety

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crossonSean Crosson
University of Chicago
Chicago, IL

Sean Crosson, Professor, University of Chicago, Chicago, IL
Education: B.A. Biology, Earlham College, 1996; Ph.D., Biochemistry and Molecular Biophysics, University of Chicago, 2002. Postdoctoral Fellow, Stanford University, 2002-2005.
Professional Experience: Chair of the graduate program in microbiology, University of Chicago (2015-present); NIH study section (PCMB, 2016-2017, ad hoc); NSF study panels (Microbial Communities; Mathematical Biology; 2014-2016); Beckman Young Investigator Award, review committee (2012-2016); Faculty, Microbial Diversity Course, Marine Biological Laboratory, Woods Hole, MA. (2015-present); Editorial board, Journal of Bacteriology (2012-present); Editorial advisory board, Molecular Microbiology (2011-present)
ASM Activities: Editorial Board, Journal of Bacteriology (2012-present); American Society for Microbiology (ASM) general meeting planning committee (2011-2014); ASM Microbe planning committee (2015-2016)
Publications: 63 publications total. Representative publications over the past 10 years: Herrou, J., Choi, V.M., Bubeck Wardenburg, J., and Crosson, S. 2016. Activation mechanism of the Bacteroides fragilis cysteine peptidase, Fragipain. Biochemistry 55: 4077-4084. Willett J.W., Herrou J., Briegel A., Rotskoff G., and Crosson S. 2015. Structural asymmetry in a conserved signaling system that regulates division, replication and virulence of an intracellular pathogen. Proc. Natl. Acad. Sci. USA 112: E3709-3718. Fiebig, A., Herrou, J., Fumeaux, C., Radhakrishnan, S.K., Viollier, P.H., and Crosson, S. 2014. A cell cycle and nutritional checkpoint controlling bacterial surface adhesion. PLoS Genetics: e1004101. doi: 10.1371/journal.pgen.1004101. Kim, H-S. Willett, J.W. Jain-Gupta, N., Fiebig, A. and Crosson, S. 2014. The Brucella abortus virulence regulator, LovhK, is a sensor kinase in the general stress response signaling pathway. Mol. Microbiol. 94: 913-925. Henry, J.T. and Crosson, S. 2013. Chromosome replication and segregation govern the biogenesis and inheritance of inorganic polyphosphate granules. Mol. Biol. Cell 24: 3177-3186. Herrou, J., Rotskoff, G., Luo, Y., Roux, B., and Crosson, S. 2012. The structural basis of a protein partner switch that regulates the general stress response of α-proteobacteria. Proc. Natl. Acad. Sci. USA 109: E1415-1423. Boutte, C.C., Henry, J.T., and Crosson, S. 2012. ppGpp and polyphosphate modulate cell cycle progression in Caulobacter crescentus. J. Bacteriol. 194: 28-35. Fiebig, A. Castro-Rojas, C.M., Siegal-Gaskins, D., and Crosson, S. 2010. Interaction specificity, toxicity, and regulation of a paralogous set of ParE/RelE-family toxin-antitoxin systems. Mol. Microbiol. 77: 236-251. Marks, M.E., Castro-Rojas, C.M., Teiling, C., Du, L., Kapatral, V. Walunas, T. and Crosson, S. 2010. The genetic basis of laboratory adaptation in Caulobacter crescentus. J. Bacteriol. 192: 3678-3688. Purcell, E.B., Siegal-Gaskins, D., Rawling, D.C., Fiebig, A., and Crosson, S. 2007. A photosensory two-component system regulates bacterial cell attachment.  Proc. Natl. Acad. Sci. USA. 104:18241-18246.
Research Interests: My research group is working to define molecular, genetic, and biochemical mechanisms that control bacterial cell physiology and infection biology. Our studies primarily center on how chemical and physical signals are received, processed, and integrated by bacterial cells. We investigate these questions in ecologically diverse bacteria including the intracellular bacterial pathogen, Brucella abortus, the freshwater bacterium, Caulobacter crescentus, and the marine photoheterotroph, Erythrobacter litoralis.

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fryeJonathan Frye
U.S. Department of Agriculture, Agricultural Research Service
Athens, GA

Jonathan Frye, Research Microbiologist, USDA, Agricultural Research Service, Athens, GA 30605
Education: PhD in Microbiology 2000 University of Georgia; BS in Biology 1993 East Carolina University; AAS in Biotechnology 1991 Alamance Community College
Professional Experience: 2003–present: Senior Scientist, USDA Agricultural Research Service, Athens, GA; 2011–present: Adjunct professor, UGA Department of Microbiology, Athens, GA; 2001–2003: Postdoctoral associate, Sidney Kimmel Cancer Center, San Diego, CA
ASM Activities: Served on the JCM editorial board 2006–2015. Attended fourteen ASM General Meetings since 1997 and author on over 30 posters. A postdoctoral associate’s and a PhD student’s abstracts were selected for oral presentations at ASM in 2014 and 2016, respectively.
Publications: (Selected Peer-Reviewed, out of 80 total)
1.    Frye, J. G., and C. R. Jackson. 2013. Genetic mechanisms of antimicrobial resistance identified in Salmonella enterica, Escherichia coli, and Enteroccocusspp. isolated from U.S. food animals. Front. Microbiol. 2013 May 23;4:135.
2.    Glenn, L.M., R. L. Lindsey, J. P. Folster, G. Pecic, P. Boerlin, M. W. Gilmour, H. Harbottle, S. Zhao, P. F. McDermott, P. J. Fedorka-Cray, G. Frye. 2013. Antimicrobial resistance genes in multi-drug resistant Salmonella enterica isolated from animals, retail meats, and humans in the U.S. and Canada. Microb Drug Resist. 2013 Jun;19(3):175–184.
3.    Frye, J. G., L. Lindsey, G. Rondeau, S. Porwollik, F. Long, M. McClelland, C. R. Jackson, M. D. Englen, R. J. Meinersmann, M. E. Berrang, J. A. Davis, J. B. Barrett, J. B. Turpin, S. N. Thitaram, P. J. Fedorka-Cray. 2010. Development of a DNA microarray to detect antimicrobial resistance genes identified in the NCBI database. Microb. Drug Resist. Mar;16(1):9–19.
4.    Frye, J. G., T. Jesse, F. Long, G. Rondeau, S. Porwollik, M. McClelland, C. R. Jackson, M. D. Englen, P. J. Fedorka-Cray. 2006. DNA microarray detection of antimicrobial resistance genes in diverse bacteria. Int. J. Antimicrob. Agents. Feb;27(2):138–150.
5.    Frye, J. G., S. Porwollik, F. Blackmer, P. Cheng, M. McClelland. 2005. Host gene expression changes and DNA amplification during temperate phage induction. J. Bacteriol. Feb;187(4):1485–1492.
Research Interests: Our laboratory studies the genetics, pathogenicity, and antimicrobial resistance of Salmonella enterica associated with food animals to improve food safety and protect human health. Salmonella causes approximately one million foodborne infections in the U.S. each year. Our goals are to identify the mobile genetic elements that carry resistance genes and to determine how they are spread to Salmonella and other bacteria in the food production environment. To achieve these goals we’ve developed microarray, real-time PCR, multiplex PCR, whole-genome sequencing, and biocide susceptibility assays. Our achievements include the identification of diverse resistance genes in Salmonella and other bacteria, as well as the mobile genetic elements that carry them, including the IncA/C, IncI1, other plasmids, and IntI1 integrons. This information has been used to develop rapid Salmonella detection and subtyping methods. We are also investigating the relationship between antimicrobial resistance and biocides used in food production. Recently we have begun exploring the role of surface water from agricultural, residential, and industrial areas in the transmission of Salmonella.

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mcdanielLarry McDaniel
University of Mississippi Medical Center
Jackson, MS

Larry S. McDaniel, Chair of the Department of Microbiology and Immunology, The University of Mississippi Medical Center, Jackson, MS
Education: B.S. Microbiology, Southeastern Louisiana University; Ph.D. Microbiology, University of Oklahoma; Postdoctoral Fellow, University of Alabama at Birmingham (Drs. David Briles and Max Cooper)
Professional Experience: Assistant Professor, University of Alabama at Birmingham; Professor, University of Mississippi Medical Center; Fellow, American Academy of Microbiology; Fellow, Infectious Diseases Society of America; Editor, mBio; Editorial Board, Infection and Immunity, and Clinical and Vaccine Immunology; Associate Editor, The Journal of Immunology
ASM Activities: I have served on several ASM committees including the Membership Committee, the Watkins Fellowship Committee, and the Minority Faculty Fellowship Committee. I have been a lecturer for the ASM Presentation Institute and the Scientific Writing and Publishing Institute. I have participated in ASM Scientific Writing and Publishing Workshops in India and South America. I have also been featured in an ASM video on Scientific Writing and Publishing.
Publications: I have published over 80 peer-reviewed articles.
Keller, L.E., Friley, J., Dixit, C., Hahm, M.H., and McDaniel, L.S.: Nonencapsulated Streptococcus pneumoniae (NESp) Cause Acute Otitis Media in the Chinchilla that is Enhanced by Pneumococcal Surface Protein K (PspK). Open Forum Infectious Diseases 2014; doi: 10.1093/ofid/ofu037.
Keller, L.E., Robinson, D.A., McDaniel, L.S.: Nonencapsulated Streptococcus pneumoniae: emergence and pathogenesis. mBio 7(2):e01792-15.2016. doi:10.1128/mBio.01792-15.
McDaniel, L.S., and Swiatlo, E.: Should pneumococcal vaccines eliminate nasopharyngeal colonization? MBio. 2016 ;24;7(3). pii: e00545-16. doi: 10.1128/mBio.00545-16
Research Interests: My research focuses on host-bacterial pathogen interactions. We have used model systems of Streptococcus pneumoniae, Acinetobacter baumannii, and Pseudomonasaeruginosa. We have also investigated host immune responses against bacterial antigens with an emphasis on vaccine development.

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raoKrishna Rao
University of Michigan
Ann Arbor, MI

Krishna Rao, MD, MS, University of Michigan, Ann Arbor, MI
Education: 9/1998–6/2001 Northwestern University, Evanston, IL. Bachelor of Arts in Mathematics; 9/2002–6/2006 Rush Medical College, Chicago, IL. Doctor of Medicine; 10/2013–4/2015 University of Michigan School of Public Health, Ann Arbor, MI; Master of Science—Clinical Research Design & Statistical Analysis; 6/2006–6/2010 Postdoctoral Training, University of Michigan Medical School, Ann Arbor, MI; Residency—Internal Medicine & Pediatrics; 7/2011–6/2013 University of Michigan Medical School, Ann Arbor, MI; Fellowship—Infectious Diseases.
Professional Experience: 7/2010–6/2011 Clinical Lecturer, Department of Internal Medicine, Division of General Medicine, University of Michigan Medical School; Ann Arbor, Michigan; 7/2013–6/2015 Clinical Lecturer, Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical School; Ann Arbor, Michigan; 7/2015–present Assistant Professor, Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical School; Ann Arbor, Michigan; 2012–2015 Procalcitonin Advisory Panel. Protocol Author and Clinical Lead. University of Michigan Health System, Ann Arbor, MI; Led the effort to implement this important biomarker in clinical practice at a tertiary care academic medical center; 2012–present Fecal Microbiota Transplant Program. Co-Founder and Administrative Director. University of Michigan Health System, Ann Arbor, MI; Established the UM stool transplant program and currently oversee its activities
ASM Activities: 2014 ASM ICAAC Task Force—ASM Committee Member; Helped with restructuring ICAAC, most notably combining it with general meeting to result in new ASM Microbe conference; 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014, Washington, DC). Symposium—Moderator and Presenter. Symposium Title: “Challenging Infections in Older Adults” Talk Title: “The Special Relationship between Clostridium difficile and Older Adults”; Organized and moderated an ASM symposium on infections in older adults; Division of Healthcare Quality Promotion (DHQP) CDI Risk Adjustment Expert Group 2016—ASM Representative & Committee Member. Centers for Disease Control and Prevention, Atlanta, GA; Was ASM representative for committee that evaluated proposed changes to how C. difficile baseline risk was modeled, which is used to calculate the standardized infection risk (SIR). Since it is a hospital quality metric, I specifically brought up the ASM concern about over-reporting colonization with C. difficile with newer PCR-based tests, and how this needs to be considered in calculation of baseline risk and SIR.
Publications: 24 Peer-Reviewed Journals and Publications; 4 Non Peer-Reviewed Journals and Publications
Research Interests:1. Diagnosis, treatment, and clinical epidemiology of Clostridium difficile infection (CDI); 2. Biomarkers and the microbiota; 3. Predictive modeling for infections; 4. Gram negative infections and multidrug-resistant organisms (MDROs). I am a PI or Co-I for four funded projects regarding these interests: 1) the systems biology of CDI; 2) the longitudinal impact of antibiotics on the microbiota; 3) the detection and prognosis of colonization with ESBL-producing Enterobacteriaceae; and 4) integrated modeling of Klebsiella pneumoniae infections. These NIH- and CDC-funded projects all leverage my experience in clinical medicine, clinical research, biostatistics, and team science to translate basic discoveries into clinical practice.

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schmidtThomas Schmidt
University of Michigan
Ann Arbor, MI

Thomas M. Schmidt, Professor, University of Michigan, Ann Arbor, MI
Education: 1978 B.S. University of Michigan; 1985 Ph.D. Ohio State University; Post Doctoral Fellowships: 1987 Scripps Institute of Oceanography and 1989 Indiana University
Professional Experience: My first faculty position was at Miami University (Ohio), I then advanced through the faculty ranks at Michigan State University. Recently, I moved to the University of Michigan where I hold a joint appointment in the Medical School and the Department of Ecology and Evolutionary Biology. This combined affiliation presents an incredible opportunity to introduce microbial ecology and evolution into the study of host-associated microbiomes. I am also in the midst of developing a campus-wide institute to foster research and education in the microbial sciences. As a recent member of scientific advisory boards for the Max Plank Institute, Genome Canada and the Department of Energy initiatives known as the “Microbial Communities Initiative” and “ENIGMA: Ecosystems and Networks Integrated with Genes”, I have worked with colleagues both nationally and internationally to help vision the future of the microbial sciences. I also stay abreast of trends in microbiological research as a regular member of review panels at the National Science Foundation and the National Institutes of Health, and as a senior editor for the ISME Journal.
ASM Activities: In addition to serving on the editorial board for Microbe, I am currently chair of General Microbiology (Division K) and a member of the Committee on Awards. I am also a member of the American Academy of Microbiology and have contributed to several of the Academy’s colloquia, including a 2016 colloquium to discuss interactions between Earth’s microbiomes and climate. I would be delighted to expand my involvement with ASM by serving on the Council on Microbial Sciences.
Publications: One measure of the overall impact of publications from the Schmidt lab is the H-index. According to Google Scholar, mine is 55 overall and 39 since 2012, with close 20,000 citations overall. Two publications from the past year highlight the research underway in the Schmidt laboratory. The first article was published in Nature Microbiology: “Exploiting rRNA Operon Copy Number to Investigate Bacterial Reproductive Strategies”. In this article we explore my long-term interest in relationships between the number of ribosomal RNA genes, genome content and bacterial lifestyles. A second article, published in Microbiome: “Variable Responses of Human Microbiomes to Dietary Supplementation with Resistant Starch” delves into the relationship between the gut microbiome and diet. This project is special in that it engages university students enrolled in an introductory Biology Course as both subjects and participants in the research – a wonderful synergy that advances both educational and research goals.
Research Interests: My current research focuses on host-associated microbiomes and is based on my background in bacterial physiology, ecology and evolution. I began as a graduate student studying the physiology of sulfide-oxidizing bacteria and then moved on to study interactions of some of the luminescent bacteria with their hosts, before launching into a career studying complex microbial communities. My attention for much of that time has been directed to studying microbial communities in terrestrial environments and their involvement in the flux of greenhouse gases. Four years ago, I moved to the University of Michigan to apply this expertise to study host-associated microbiomes.

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vollmerAmy Cheng Vollmer
Swarthmore College
Swarthmore, PA

Amy Cheng Vollmer, Isaac H. Clothier, Jr. Professor of Biology at Swarthmore College, Swarthmore, PA
Education: She began her training at Rice University where she received her BA in Biochemistry in 1977. She then earned PhD in Biochemistry in 1983 from the University of Illinois, Urbana-Champaign.
Professional Experience: After a postdoctoral fellowship in the Division of Immunology (Stanford Medical School) she spent four years at Mills College before joining the faculty at Swarthmore. There she has served two terms as biology department chair, was the inaugural Luhrs Fellow at Swarthmore’s Center for Leadership and Innovation, and most recently, was one of four founding faculty members in Swarthmore’s Summer Scholars Program that focuses on developing young successful scholars in STEM. She has been a member of the Gordon Research Conference Microbial Stress Response community since 1994 and co-chaired the conference in 2000. In 2006 she was received the Carski Foundation Distinguished Undergraduate Teaching Award from the ASM. She has led the Waksman Foundation for Microbiology since 2007 as its fourth president. She was an ASM Distinguished Lecturer from 2011 to 2013. In 2014, she was recognized as a National Academies Summer Institute Education Fellow in the Sciences.
ASM Activities: Amy’s involvement in ASM activities reflects her dual interests in research and teaching. She has been a continuous member of ASM (and the Eastern PA ASM branch) since 1990. She has served on the branch’s education committee since 1999, often hosting the annual education speaker. A member of the ASM’s education board’s undergraduate education committee, she served the first editor-in-chief of Microbiology Education (now the Journal for Microbiology and Biology Education) from 1999–2003. As a member of the ASMCUE community, she has presented at the annual conference in 2001, 2002, 2006 and 2012. As chair of the student membership committee (part of the ASM’s Membership Board) from 2003-2006, with her focus on students as the ‘future of ASM’, the number of student chapters grew to over 100, through bylaws changes to allow establishment a student chapter without the support of a local branch as well as multi-campus student chapters. She served the General Microbiology Division (I) as chair-elect, chair and advisor from 2008-2010. She has been a member of: ASM Founders Distinguished Service Award Nominating Committee, Carski Undergraduate Teaching Award nominating committee, Career Development Grants for Postdoctoral Women Committee, Center for the History of Microbiology/ASM Archives Committee (CHOMA). Since 2011, she has been a member of ASM’s General Meeting and now Microbe Planning Committee.
Publications: Amy has nearly 50 articles, chapters, invited blog posts and reviews in research as well as in teaching, mentoring and pedagogy.
Research Interests: Her research focuses on (1) microbial stress response: regulation as well as environmental applications and (2) change in gut microbiome profile of small rodents and birds during dietary limitation/metabolic extremes. She is intensely interested in the teaching of intermediary metabolism and has found a purpose in career mentoring for undergraduates, graduate students, postdoctoral fellows and young faculty with special emphasis on inclusion.

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wylieKristine Wylie
Washington University School of Medicine
St. Louis, MO

Kristine M. Wylie, Assistant Professor of Pediatrics, Washington University School of Medicine, St. Louis, Missouri
Education: 2003-2009, Saint Louis University School of Medicine, Doctoral Program in Biomedical Sciences, Department of Molecular Microbiology and Immunology, Dissertation: Manipulation of virus-host interactions to determine protein function, Mentor: Lynda A. Morrison, Professor; 1993-1996, Southern Illinois University at Edwardsville, B.A., cum laude in Biology
Professional Experience: July 2015 – Present, Assistant Professor of Pediatrics, Department of Pediatrics, Washington University School of Medicine, Studies of the microbiome, infectious diseases, and microbe-host interactions; February 2013 – June 2015, Research Instructor, Department of Pediatrics, Washington University School of Medicine, Microbial genomics research, with emphasis on studying the human virome and infectious diseases; October 2009 – January 2013, Postdoctoral Research Associate, The Genome Institute, Washington University School of Medicine, Mentor: George Weinstock, Professor, Metagenomic analysis of the human virome; discovery of novel microbes; May 1996 – May 2003, Manager and research technician, Physical Mapping Group, The Genome Center, Washington University School of Medicine, Supervisor: Dr. John McPherson, Managed projects and personnel for a number of large-scale genome projects, including human, mouse, chicken, and zebrafish
ASM Activities: 2007-Present, Member, ASM; 2007-2009, Communications Officer, ASM Graduate Student Chapter, Saint Louis University; 2009, Secretary, ASM Graduate Student Chapter, Saint Louis University
Publications: 40 publications, 1 Book Chapter
Research Interests: My research broadly aims to understand the role of the microbiome in health and disease. As a trained virologist, I have a particular interest in viruses, which are often overlooked in studies of the microbiome. I use genomics, microbiology, molecular biology and in vitro model systems to understand important clinical problems (including unexplained pediatric fevers, preterm birth, and many others). I also have interest in applying genomics technologies to study infectious disease outbreaks and to develop methods that may lead to improved diagnostic tests. I am an enthusiastic adopter of new technologies and techniques for studying microbes and microbial communities.

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Aarbeston Best
Hope College
Holland, MI

Aaron A. Best, Ph.D., Hope College, Holland, MI
Education: My first formal exposure to microbiology was during my undergraduate training at William Jewell College (Liberty, MO), a small private liberal arts college. While obtaining a B.A. in Biology (1996) there, I had a summer undergraduate research experience in molecular phylogeny based on sequencing of ribosomal RNA that lead me to obtain a Ph.D. in Microbiology from the University of Illinois, Urbana-Champaign in the laboratory of Dr. Gary Olsen (2001) where I focused on the evolution of transcription systems in the Archaea and Eucarya. This was followed by a post-doctoral position with Dr. Carl Woese, also at Illinois in comparative genomics and molecular evolution.
Professional Experience: Throughout my graduate training, I had the opportunity to teach undergraduates and realized that I wanted to pursue a career in academia that would allow me to maintain a serious research program and that would support excellence in teaching. This led me to return to the liberal arts college environment and my current position as the Harrison C. and Mary L. Visscher Professor of Genetics at Hope College (2004 to present). In my role as faculty at a primarily undergraduate institution (PUI), I have maintained an active, extramurally funded research program (federal and foundation sources) that incorporates undergraduates into all aspects of the research process. Additionally, I have focused on combining research and teaching programs to become a single endeavor. I have taught and participated at a programmatic level in the HHMI SEA-PHAGES program since the program’s inception in 2008, incorporated research projects into the general microbiology laboratory course that I teach, and recently started a year-long course for first year students focused on the microbial ecology of the local watershed using 16S rRNA sequencing approaches and sequencing of genomes of bacteria isolated from the watershed.
ASM Activities: Throughout my graduate and professional career, I have benefited from the myriad opportunities ASM provides. My first meeting was in Chicago during graduate school, and I have been attending the General Meeting (now ASM Microbe) since then. As I transitioned to a career at a PUI, I began attending the ASM Conference for Undergraduate Educators (CUE), which has proven to be an invaluable resource for me. After attending several ASMCUE meetings, I had the privilege of co-organizing the meeting in 2007. My undergraduate research students have presented work at national ASM meetings, and two have received ASM-URF awards. In 2014, I presented at an ASM General Meeting workshop, “Getting started as a microbiologist at a primarily undergraduate institution,” and I have presented invited talks at both the General Meeting and the Michigan Branch meeting.
Publications: During my time at Hope College, I have published 23 peer reviewed papers, 14 of which include 90 undergraduate co-authors.
Research Interests: My current research is fully embedded with my teaching and centers on comparative microbial genomics of environmentally derived Escherichia populations, molecular ecology of fresh water systems, and integration of large scale data sets into genome scale metabolic models of bacteria. ASM has been a vital part of my professional development, and I look forward to serving the society by bringing the perspective of an active teacher/scholar at a PUI to the governance of the society.

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craftDavid Craft
Penn State Milton S. Hershey Medical Center and College of Medicine
Hershey, PA

David W. Craft, Professor and Interim Chair, Department of Pathology; Medical Director, Microbiology, Penn State M. S. Hershey Medical Center / Penn State College of Medicine, Hershey, PA
Education: B.S. Microbiology, University of Alabama; M.S. Microbiology, University of Alabama; Ph.D. Medical Microbiology, University of Georgia College of Veterinary Medicine; Post-Doctoral Fellow, Clinical Microbiology, UNC Hospitals, Chapel Hill, NC; Diplomate, American Board of Medical Microbiology
Professional Experience: Interim Chair, Department of Pathology, Penn State Milton S. Hershey Medical Center, Hershey, PA; Medical Director of Microbiology, Department of Pathology, Penn State Milton S. Hershey Medical Center, Hershey, PA; Director, Wound Infection Department, Walter Reed Army Institute of Research, Silver Spring, MD; Commander, 9th Area Medical Laboratory, Aberdeen Proving Grounds, MD; Medical Director / Chief, Infectious Disease Laboratory, Walter Reed Army Medical Center, Washington, DC; Director, Microbiology, Academy of Health Sciences, Army Medical Department Center & School, Fort Sam Houston, TX; Director, Microbiology / Immunology Services, Department of Clinical Investigation, Dwight David Eisenhower Army Medical Center, Augusta, GA; Director, Microbiology, 10th Medical Laboratory, Landstuhl, Germany; Director, HIV/Immunology, 10th Medical Laboratory, Landstuhl, Germany; Director, Virology, Letterman Army Medical Center, San Francisco, CA; Director, Reference Bacteriology, Letterman Army Medical Center, SF,CA.
ASM Activities: Member, Professional Practices Committee (2012 - 2017); Member, Clinical Microbiology Mentoring Committee (2012-2017); Council Policy Committee (2015-2016); Chair, Division C (2014-2015); Chair- Elect, Division C (2013-14); Planning Committee, Microbe 2016 Annual Meeting (2015-2016); Vision of the Future Leadership Team Steering Committee (2015-2017); Planning Committee, General Meeting 2015(2014-2015); Member (ASM Liaison) Pathology Workforce Summit PhD Task Force (2014-15); Member, Strategic Task Force: Review of Meetings (2014); Member, Becton-Dickinson / American Academy of Microbiology Award for Research in Clinical Microbiology Selection Committee (2013-2014); Member, bioMérieux / American Academy of Microbiology Sonnenwirth Leadership Award Selection Committee (2013-2014); ASM/APHL Sentinel Level Laboratory Protocol Working Group (2012-15); Editorial Board, Journal of Clinical Microbiology (2010 – 2018); Editor, Quality Control Category, Clinical Microbiology Portal Question/Answer (2012-2016); Member, Board of the American College of Microbiology (2009 - 2012); Member, Clinical Microbiology Task Force (2010 - 2011); Steering Committee and Team Leader, American Academy of Microbiology Colloquium: Clinical Microbiology in 21st Century (2006); Member, Committee on Postgraduate Educational Programs (2003 - 2009); Member, Diplomacy Test Committee, American Board of Medical Microbiology (2003 - 06); Member, American Academy of Microbiology Colloquium: The role of the Clinical Microbiology lab in detection, identification & confirmation of biological agents(2000-02).
Publications: Peer-reviewed-45; Non-peer reviewed – 93; Book Chapters - 10
Research Interests: Traumatic wound and skin microbiome, emerging antimicrobial resistance, orthopedic biofilm, tropical enteric disease, patient care outcomes of infectious diseases

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depascalisRoberto De Pascalis
U.S. Food and Drug Administration
Silver Spring, MD

Roberto De Pascalis, M.D., Laboratory of Mucosal Pathogens and Cellular Immunology, Office of Vaccines Research and Review, Center for Biologic Evaluation and Review, Food and Drug Administration, Silver Spring, MD
Education: Medical Doctor Degree, University of Naples, Italy; Specialty in Microbiology and Virology, University of Naples, Italy
Professional Experience: Resident, Department of Molecular Biology and Pathology, University of Naples, Italy; Visiting Fellow, Laboratory of Tumor Immunology and Biology, NIH, Bethesda, MD; Visiting Associate, CBER, FDA, Bethesda, MD; Research Microbiologist, LMPCI, CBER, FDA, Silver Spring, MD
Publications (Selected): De Pascalis R, Taylor BC and KL Elkins. Diverse myeloid and lymphoid cell subpopulations produce gamma interferon during early innate immune responses to Francisella tularensis live vaccine strain. Infect Immun. 2008; 76(9):4311-4321; Elkins KL, Colombini SM, Krieg AM, De Pascalis R. NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS. Microbes Infect. 2009; 11(1): 49-56; De Pascalis R, Chou AY, Bosio CM, et al. Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen, F. tularensis LVS. PLoS Pathogens. 2012; 8(1) e1002494; De Pascalis R, Chou AY, Ryden P, et al. Models derived from in vitro analyses of spleen, liver, and lung leukocyte functions predict vaccine efficacy against Francisella tularensis LVS. mBio. 2014; 5(2): e00936-13; De Pascalis R, Mittereder L, Chou AY, et al. Francisella tularensis vaccines elicit concurrent protective T- and B-cell immune responses in Balb/cByJ mice. PloS One. 2015; 10(5) e0126570; De Pascalis R, Mittereder L, Kennet NJ, and Elkins KL. Activities of murine peripheral blood lymphocytes provide immune correlates that predict Francisella tularensis vaccine efficacy. Infect Immun. 2016; 84(4):1054-1061; Elkins KL, Kurtz SL, De Pascalis R. Progress, challenges, and opportunities in Francisella vaccine development. Expert Rev Vaccines. 2016 May 3:1-14.
Research Interests: My current research focuses on the nature of vaccine-induced protection determined by Live Vaccine Strain (LVS) of Francisella tularensis, an intracellular bacterium, and aims to establishing clinically predictive correlates of protection. Combining functional in vitro co-culture assays with analyses of mRNA derived from activated leucocytes of mice vaccinated with LVS or LVS variants, which provide differential vaccine protection, allowed the identification of a panel of immunologic markers that correlate with protection. The resulting correlates of protection are being evaluated in different animal models to validate their ability to predict the outcome of novel vaccines’ efficacy. LVS can be used as a prototypic vaccine candidate as well as an immunological infection model. Therefore, this approach may be applicable to other intracellular pathogens and may ultimately complement vaccine efficacy clinical trials. The role of interferon gamma producing cells during innate immune response has also been of particular interest in my studies. We have demonstrated that not only natural killer and T cells, but also other myeloid cells, appear to be involved in IFN- production, and that their activation may be T or B independent. Ongoing studies are especially focused on the role of subtypes of dendritic cells that may contribute to a successful transition from innate to specific immunity.

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diritaVictor DiRita
Michigan State University
East Lansing, MI

Victor DiRita, Rudolph Hugh Endowed Chair, Department Chair, Michigan State University
Education: B.S. Michigan State University – 1980; Ph.D. Purdue University – 1986; Postdoctoral – Harvard Medical School – 1986-1991
Professional Experience: 1991-2015, Assistant, Associate, Full Professor, Department of Microbiology & Immunology, University of Michigan; 2010-2015 Associate Dean, Graduate & Postdoctoral Training, University of Michigan Medical School
ASM Activities: My ASM activities have been varied, and they are noted below with some annotations to make some particular points. My focus has been on contributing to the Society as much as possible when asked to serve. We are a member-driven organization whose mission is to advance the microbial sciences. As an ASM Member, I have tried to serve that mission from many different angles. Member since 1981; Elected, American Academy of Microbiology, 2009; ASM/Waksman Foundation Lecturer (’99-’01); Faculty, ASM/NAS/HHMI Molecular Pathogenesis Course, Santiago, Chile (’99); International Fellowship Review Committee; (’01-;03); General Meeting/Microbe Session Convenor, (’94,’96,’99,’01,’06,’11,’15); Division B Chair-Elect, Chair, Council (’03-’05); Division Group II Rep (’08-’10); President Nominating Committee (’09, ’13); Conferences Committee (’12-curr); Chair, Membership Board (‘12-curr)—during this period the Membership Board developed i) the ASM Scientific Advisory Committee to incorporate and work with Divisions; ii) the Advance Your Science Program to support member scholarly activities; iii) the Microbe Mentor column in Microbe magazine and now in our online platform. Chair, Microbe HMB Track (16 - curr); Member, ASM Council Policy Committee (‘12 -‘16); Member, Task force on Divisions (’12)—led to placement of Divisions under Membership within the ASM structure. Member, ICAAC Strategic Task Force (‘14)—led to development of the current Microbe (GM + ICAAC) meeting we are all so proud of! Member ASM Futures Project Team (‘14)—led to re-envisioning the ASM governance structure and development of the Council on Microbial Sciences (COMS); Editorial Board, IAI, (’94-’99); Editor, IAI (’99-’09); Editorial Board, J. Bacteriol. (’99-’09); Editor, J. Bacteriol (’09-curr.); Contributor, ASM Microbial Sciences Blog (curr.)
Publications: Please go to https://www-ncbi-nlm-nih-gov.proxy1.cl.msu.edu/pubmed/?term=dirita+vj on NCBI (dirita vj[Author]). Our most recent paper was published in mBio in November 2016.
Research Interests:  Genetic control of microbial pathogenicity; host-microbe-microbiome interactions; transcription regulatory mechanisms; chemical biology and therapeutic discovery. Over the years, our work has been focused primarily on the pathogens Vibrio cholerae, Campylobacter jejuni, and Streptococcus pyogenes. We study the biology and pathogenicity of microbes at different scales: from questions around single molecule biology and protein-protein interactions governing key processes, to genomic-level interrogation in animal models of infection, to the role of complex microbiota in pathogen-host biology.

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ferrellRebecca Ferrell
Metropolitan State University of Denver
Denver, CO

Rebecca V. Ferrell, Professor of Biology, Metropolitan State University of Denver, Colorado
Education: B.S., 1978, Missouri State University, biology major, English minor; M.S., 1980, Missouri State University, immunology in murine model, Richard Myers lab; PhD, 1990, University of Missouri Medical School, microbial genetics in mycoplasmas, Mark McIntosh lab; Post-doc, 1990-91, University of Colorado, RNA selex of viral polymerases, Larry Gold lab
Professional Experience: I joined the Metropolitan State faculty in 1991, earning tenure in 1996 and Professor in 2000. Teaching is our main focus. I teach 24 credits annually; my rotation includes General Microbiology, Microbial Ecology, Microbial Genetics, Virology, and Biology of Women. Before joining the faculty, along with the usual teaching and research assistant jobs, I enlisted in the U.S. Army Reserve, training as a 91-S Environmental Health specialist, the military equivalent of public health work. I also taught middle school math and science, and college biology as an adjunct professor to Americans stationed in West Germany.
ASM Activities: I “grew up” scientifically in the Missouri Branch, where my first grad student research presentation won a prize, very encouraging! I appreciate the nurturing environment Branches offer, along with the great diversity of science national ASM’s journals and meetings make available. Rocky Mountain Branch (RMB-ASM) has given me colleagues and collaborators, as well as friends. I have been active in RMB-ASM since 1991, serving 3 terms as President and in most other Branch offices, including 3 terms on ASM’s Council. In 2014, I was elected at-large from Branches to ASM’s Council Policy Committee (CPC) where I have had the privilege of serving during the revision of ASM’s governance. I was in the working group tasked to propose a new role for ASM’s existing Council, when the idea of COMS emerged. I would very much like to see it through next steps, as it develops a culture of looking at the “big picture” in microbial sciences and organizing itself to help the Society respond as a leader in the challenges and opportunities that lie ahead.
Publications: Recent publications are limited because most of my work is teaching. Here is what I did on my recent sabbatical leave: L. Sayavedra-Soto, R. Ferrell, M. Dobie, B. Mellbye, F. Chaplen, A. Buchanan, J. Chang, P. Bottomley, and D. Arp. 2014. Nitrobacter winogradskyi transcriptomic response to low and high ammonium concentrations. FEMS Microbiology Letters 4/12/14. J. Perez, A. Buchanan, B. Mellbye, R. Ferrell, JH Chang, F. Chaplen, PJ Bottomley, DJ Arp and LA Sayavedra-Soto. 2014. Interactions of Nitrosomonas europaea and Nitrobacter winogradskyi grown in co-culture. Arch Microbiol 171(1):79-89.
Research Interests: Metro State is a primarily undergraduate university, and the Biology department does not have a graduate program, although I do also serve as adjunct graduate faculty at University of Colorado Denver. Main interests are water quality and nitrification, currently including a long-term water quality survey of a local waterway in cooperation with EPA, a study of E. coli in Canada geese, and cloning and expression of quorum sensing response regulators from Nitrobacter.

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jacobsJonathan Jacobs
MRIGlobal
Kansas City, MO

Jonathan Jacobs, PhD, Senior Advisor, MRIGlobal, Gaithersburg, MD
Education: Postdoctoral Research Fellow (National Cancer Institute, NIH, Bethesda, MD, 2008) Ph.D. Cell Biology & Molecular Genetics (University of Maryland, College Park, MD, 2006) B.S.Ag. Plant Sciences (University of Arizona, Tucson, AZ, 1999)
Professional Experience: Senior Advisor, Global Health Security & Diagnostics, MRIGlobal (2016 – Present); Principal Scientist, Biosurveillance Division, MRIGlobal (2013 – 2016); Senior Scientist, Biosurveillance Division, MRIGlobal (2010 – 2013); Scientist I, Antibody Discovery & Protein Engineering, MedImmune (2009 – 2010). Jonathan Jacobs Ph.D. has over sixteen years of experience in bioinformatics, molecular genetics, and cell line engineering. He is currently the Bioinformatics Team Leader for the DTRA funded Sample-to-Sequence program where a multi-organizational team is developing a deployable metagenomics analysis pipeline for use in clinical diagnostics laboratories. He is also the principal architect behind a field deployable metagenomics system being routinely used for a US Government operational microbial forensics program. Dr. Jacobs is actively leading the development of systems for the future of mobile laboratory operations, including an ultraportable, ruggedized “lab in a backpack” designed for extended field missions in epidemiology, microbial ecology, and biosurveillance. Dr. Jacobs also actively partners with researchers in Academia, and his team has played an important role in understanding the host response and pathogenesis of alphaviruses in human cells. He joined MRIGlobal in 2010, and is currently is a Senior Advisor in MRIGlobal’s Global Health Security & Diagnostics division.
ASM Activities: 2017 ASM Biothreats 2017 (Attendee, Workshop Moderator, Poster Presenter); 2016 Coalition Member, ASM Next Generation Sequencing Coalition Meeting (Washington, DC); ASM Journal of Clinical Microbiology (Peer Reviewer); ASM Biodefense 2016 (Attendee; Poster Presenter (3)); 2014 ASM General Meeting 2014 (Attendee; Poster Presenter (1)); ASM Biodefense 2014 (Attendee; Poster Presenter (1)); Member of ASM since 2011
Publications: 13 publications
Research Interests: Pathogen genomics and bioinformatics; Biosurveillance of biological threat agents and emerging infectious diseases; Development of diagnostic signatures for early detection of exposure; Microbial forensics and cell line engineering; Developing systems, technologies, training for fieldable diagnostic systems

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marloweElizabeth Marlowe
Roche Molecular Systems Inc.
Pleasanton, CA

Elizabeth M. Marlowe, PhD, D (ABMM), Director Medical Affairs, Microbiology, Roche Molecular Systems, Inc., Pleasanton, Ca
Education: Bachelor of Science: 1989-1993, University of Arizona, Tucson, AZ, Molecular and Cellular Biology, Minor: Mathematics/Chemistry; Master of Science: 1993-1995, University of Arizona, Tucson, AZ, Environmental Microbiology; Ph.D.: 1995-1999, University of Arizona, Tucson, AZ, Environmental Microbiology; Postdoctoral Fellow: 1999-2001, UCLA Medical Center, Los Angeles, CA, Clinical/Public Health Microbiology
Professional Experience: 2016 Director of Medical Affairs, Microbiology, Roche Molecular Systems, Incorporated, Pleasanton, CA; 2015-2016 Technical Director of Microbiology, Kaiser Permanente, TPMG Regional Reference Laboratories, Berkeley, CA; 2005- 2015 Assistant Director of Microbiology and Molecular Testing, Kaiser Permanente, SCPMG Regional Reference Laboratories, North Hollywood, CA; 2002-2005 Research Scientist I, Research Scientist II, Senior Scientist, Gen-Probe Incorporated, San Diego, CA; 2001-2002 Research Scientist, Project Coordinator, Wadsworth Anaerobe Laboratory, Brentwood Biomedical Research Institute, Los Angeles, CA
ASM Activities: National: 2015-2016 ASM/CDC EBLMPG Diagnostic Accuracy of C. difficile Working Group and Expert Panel; 2016 ASM Membership Meeting, Washington DC; 2013-2015 American Society for Microbiology Sonnenwirth Award for Leadership Selection Committee; 2011 American Society for Microbiology Division C, Chair Nominating Committee; 2006-2012 American Board of Medical Microbiology Part I Exam Committee. Chapter: 2015-2017 Southern California American Society for Microbiology, Immediate Past-President; 2013-2015 Southern California American Society for Microbiology, President; 2011-2013 Southern California American Society for Microbiology, President Elect; 2006-2016 Southern California American Society for Microbiology Annual Meeting Committee; 2006-2009 Southern California American Society for Microbiology, Elected Board Member; 2002-2015 Southern California American Society for Microbiology Spring Symposia Committee
Publications: 20 Papers Peer Reviewed; 3 Papers Non Peer Reviewed; 2 Case Studies; 11 Book Chapters; 26 Abstracts and Presentations
Research Interests: Dr Marlowe’s research areas of interest are focused on new infectious disease technology to improve and drive infectious disease surveillance, diagnosis and treatment through the development and translation of high quality diagnostic laboratory methods for use in evidence-based research and daily practice.

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schmidtmMichael Schmidt
Medical University of South Carolina
Charleston, SC

Michael G. Schmidt, Ph.D., Professor and Vice Chairman, Department of Microbiology and Immunology, and Professor of Stomatology & Craniofacial Biology, Medical University of South Carolina, Charleston, South Carolina
Education: University of Illinois, Chicago, 1975-1978, B.S., Biological Sciences; Indiana University, Bloomington, 1980-1981, M.A., Microbiology; Indiana University, Bloomington 1981-1985, Ph.D., Microbiology
Professional Experience: Director, Office of Special Programs, Medical University of South Carolina, Medical Charleston, South Carolina. January 2002-2016; Professor and Vice Chairman, Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina. July 2001-present; Professor of Craniofacial Biology, (Joint Appointment, July 2009), College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina. July 2009-Present; Professor of Stomatology, Department of Stomatology (Joint Appointment July 2002) College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina. July 2002-Present; Director, Joint Environmental Studies Program, Medical University of South Carolina and the University of Charleston, 1999-2002; Professor of Microbiology and Immunology, Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina. July 1999-2001; Associate Professor of Microbiology and Immunology, Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina. July 1994-1999; Assistant Professor of Microbiology and Immunology, Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina. April 1989-1994; Postdoctoral Fellowship, State University of New York at Stony Brook, Department of Microbiology. April 1985-April 1989; Associate Instructor, Indiana University 1980-1985
ASM Activities: Regular Contributor to This Week in Microbiology, 2011-Present (~140 Episodes); Editorial Board, Applied and Environmental Microbiology 2016-Present; Host of ICAAC Live 2013, 2014, 2015; Member of the Membership Board, 2008-Present; Chair, Branch Organization Committee 2008-Present; Region IV Representative Branch Organization Committee, 2004-2008; Member, ASM Communications Committee, 1999-2011; Chair, Subcommittee for the Review of the Public Communications Web Resources, ASM Communications Committee 2004; Associate Editor, Microbe World Radio, 2006-2008; Member, Distance Education Committee, Education Board (1994-2000); Member, Centennial Heritage Committee, 1996-1999; Microbiology Careers Poster Committee, 1998
Publications: 118 published papers and reviews
Research Interests: Control of healthcare associated infections and other areas of infection control; Phage Therapy; The role that the human microbiome plays in the development of metabolic syndrome and liver disease such as NASH
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Agar Art Calendar

agar-art-calendar

ASM Agar Art Calendar (July 2016 - June 2017)

Featuring the winners of the 2015 Agar Art Contest, along with People's Choice winners, the Agar Art Calendar is a first of its kind!
Available for $18 (includes domestic shipping), this calendar is a must have for any microbiology fan!

Sample Images:
agar-art-sample1 agar-art-sample2

 

Thank you for your interest.  Sorry, we're sold out. There are no more calendars available.

Governance Election FAQs

What is the main difference between the old governance structure and the new one?

When were the bylaws changes approved and who approved them?

What happened to the Council Policy Committee (CPC) and Council?

What is replacing the CPC and Council?

What is the difference between the Board of Directors and the Council on Microbial Sciences?

Who nominated the candidates and who selected the slate?

Which positions are on the ballot?

Why are the 27 Division and 35 Branch Councilors not on the ballot?

Who appoints the two COMS representatives to the Board of Directors?

Why are there staggered terms for members of COMS and BOD?

Where can I find out how long my Division and/or Branch representative is scheduled to serve?

 

What is the main difference between the old governance structure and the new one?
The new Board of Directors (BOD) and Council on Microbial Sciences (COMS) are more nimble and able to more effectively plan.  Program Board and Committee Chairs will serve on COMS to more aptly contribute to the programmatic and scientific functions of the Society.  Additionally, seats have been reserved to ensure representation from both early career scientists and international members.

When were the bylaws changes approved and who approved them?
Bylaws changes approved by membership on September 5, 2016.

What happened to the Council Policy Committee (CPC) and Council?
Following the approval of the bylaws the CPC and Council were disbanded and a Transition Council was approved to serve through the end of the election period (February 25, 2017).

What is replacing the CPC and Council?
Two new governance bodies were created with terms beginning July 1, 2017:
o    Board of Directors (BOD)
o    Council on Microbial Sciences (COMS)

What is the difference between the Board of Directors and the Council on Microbial Sciences?
Board of Directors (BOD):

  • To set the strategic direction and uphold the objectives of the Society, authorize policy matters, direct fiduciary, legal, and business decisions, and hire, oversee, and work in partnership with the CEO
  • Consists of 5 officers (President, President-Elect, Past President, Treasurer, and Secretary), the ASM CEO, 2 Directors appointed by COMS (see below), and 6 At-Large Directors voted on by the ASM membership
  • Directors’ terms—three years, renewable once, staggered

Council on Microbial Sciences (COMS):

  • To support the work of ASM by prioritizing the scientific focus of the Society and identifying upcoming opportunities in microbial sciences and scientific trends to ensure effective programs and scientific activities that benefit the members and the scientific community at large
  • To consist of a Chair and Vice Chair (voted upon by COMS), the 5 officers, the ASM CEO, and the Academy Board of Governors Chair (all of whom are non-voting members), Program Board/Committee Chairs, 35 Councilors selected by their respective Branches, 27 Councilors selected by their respective Divisions, 8 additional Division Councilors (to balance out the number of Branch:Division members), and 10 At-Large Councilors voted on by the ASM membership
  • Councilors’ terms—three years, renewable once, staggered


Who nominated the candidates and who selected the slate?

In November 2016, a Nominating Committee was formed. Past President Lynn Enquist (Princeton) chaired the committee and members were: Avery August (Cornell), Mya Breitbart (Univ of South Florida), Peter Gilligan (Univ of North Carolina School of Medicine), Deborah Hogan (Dartmouth), Mary Sanchez-Lanier (Washington State Univ), Vanessa Sperandio (Univ of Texas Southwestern), and Judith Lovchik (Indiana State Dept of Health Labs). 

A Call for Nominations to fill slots on the Board of Directors (BOD) and on the Council on Microbial Sciences (COMS) was distributed to the entire ASM membership. We provided details on the ideal profiles and duties for the various slots to be filled, including the slots that CPC in October designated for early career scientists and international members.

We received 184 nominations. Candidates submitted brief CVs and statements expounding on their skills, knowledge, and expertise that qualified them for the position as well as their vision for the future of ASM and the microbial sciences. 

In December 2016, all nomination submissions were reviewed and discussed by the Nominating Committee. The final slate of candidates was developed by vote of the Nominating Committee


Which positions are on the ballot?
 

  • President-Elect
  • Secretary
  • 6 At-Large BOD positions: 1 slot reserved for Early Career Scientist; 1 slot reserved for International Scientist
  • 10 At-Large COMS positions:  1 slot reserved for Early Career Scientist; 2 slots reserved for International Scientist


Why are the 27 Division and 35 Branch Councilors not on the ballot?

These representatives are named by their respective Division/Branch to serve on COMS, thus they are not included on ballot The 8 additional Division Councilors will serve a one-year term on COMS, and a new process for their selection will begin in 2018.

Who appoints the two COMS representatives to the Board of Directors?
The Directors to serve as representatives from COMS to BOD will be determined by COMS at its June meeting.

Why are there staggered terms for members of COMS and BOD?
Per ASM bylaws, both BOD and COMS have staggered three-year terms for all positions. Since this is the first election, to introduce staggered terms, the CPC decided to have three different cohorts of seats—one year, two year, and three years. This is occurring only this year; after this all seats will be for a three-year term and renewable once.


Where can I find out how long my Division and/or Branch representative is scheduled to serve?
More information about which Divisions and Branches were randomly selected to serve a one-, two-, or three-year term can be found here Term Lengths for COMS Councilors

 

 

Join the Clinical Microbiology Conversation

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ASM’s CLINICAL LISTSERV - GET TWO MONTHS FREE!

Everyday your peers and colleagues are participating in the most extensive and robust discussion of all things Clinical Microbiology – and you can too!  Join the group whose recent discussions include:

  • How are you handling Yersinia cultures?
  • Does your lab charge for antibiograms?
  • Looking for lab to type Staph aureus to see if it is the USA300 strain
  • Recommendations for verifying BD BACTEC FX plastic blood cultures bottles
  • Maldi users: How do you differentiate E. coli from Shigella?

FREE TRIAL:  Try it for free today! Simply send an email to divcnet@asmusa.org for a 2-month trial.  At the end of 2-months you’ll be given the option of joining ASM – memberships start at $22!

LEARN MORE: ASM membership delivers top benefits and resources for clinical microbiologists.

JOIN ASM TODAY: Participation in ASM’s clinical microbiology listserv is just one of the benefits of ASM membership.  If you prefer to join ASM today you’ll receive all of 2017 for the price of 2016 membership.  Join at asmscience.org/join.


Send an email today to start participating!

 

Description of New Governance Bodies

BOARD OF DIRECTORS (BOD)

The BOD has the primary fiduciary responsibility for governance and the exercise and assignment of power of authority for the Society. It is the highest governing body of the Society and oversees all other bodies and functions. The BOD’s role includes:

  • Setting the strategic direction and upholding the objectives of the Society
  • Authorizing policy matters
  • Directing fiduciary, legal , and business decisions
  • Hiring and overseeing the work of the CEO
  • Upholding the strategies and measuring progress through objectives
  • Ensuring that the Society’s property, funds, and affairs are handled in conformity with the Bylaws and within the Articles of Incorporation of the Society under the statutes of the District of Columbia (D.C.)
  • Approving an annual budget

The BOD delegates to the COMS the role of identifying trends in science and suggesting programs that best capture and serve the future of microbial sciences and its workforce and reserves for itself the role of approving them. The BOD delegates to the CEO responsibility for leading and managing operations. The BOD does not operate as an “outside examiner” of the Society; rather, it supports the roles of the COMS, Program Boards/Committees, and CEO in a constructive partnership. The role of the BOD is to govern, while the COMS is responsible for scientific activities and the CEO is responsible for implementation and operations.

Broadly defined characteristics of an exception al board include, but are not limited to:

  • Works in constructive partnership with the COMS, Program Boards/Committees, and CEO
  • Is mission driven, articulating a compelling vision to ensure congruence between decisions and core values
  • Sets the strategic direction, engaging in discussions and deliberations which affect the Society’s direction in the long run
  • Presents a culture of inquiry, respect , and debate that leads to sound strategic decisions
  • Is independent -minded, putting forward the interests of the Society before anything else
  • Develops a culture of transparency, ensuring that members and all stakeholders have access to appropriate and accurate information regarding finances, operations, and outcomes
  • Adheres to the highest standards of integrity by managing conflicts of interest and establishing appropriate mechanisms of oversight
  • Is a careful steward of the Society ’s resources, by linking bold visions and plans to appropriate financial prudence
  • Is results-oriented, measuring and evaluating the performance of various bodies and programs without managing them directly
  • Operates under best practices in fulfilling its governance duties
  • Evaluates its own actions for continuous learning and improvement
  • Revitalizes itself through planned turnover and inclusiveness based on diversity at all levels (gender, race, geography, sexual orientation, scientific discipline)

In concert with the broadly defined characteristics of an exceptional board, a Director should:

  • Be an individual who is a leader in the field of microbial sciences as viewed by his/her peers and has a stake in microbial sciences;
  • Be an individual who is selected for this role on the basis of his/her skills in governing and has experience and competencies in this arena;
  • Be familiar with ASM bylaws and governance structure, in particular with the roles and responsibilities of key components of the organization, such a s the BOD, COMS, and CEO;
  • Consider the needs of the entire organization, not the specific region or section from which he /she was elected;
  • Understand the decision process and chain of command for both the volunteer leaders and the headquarters staff;
  • Maintain respect for other Directors and their opinions; the BOD should be a place where it is safe to disagree without being disagreeable. Once decisions are made, though, the BOD speaks with one voice, and responsible Directors do not publicly voice their dissent with decisions made by the BOD;
  • Study and become knowledgeable about all subjects on which a decision is needed;
  • Know when and how to present views on policy or issues, knowing that the BOD needs to function as a group that makes decisions and is not simply a discussion forum;
  • Set personal goals as a volunteer leader in support of the Society's mission and strategic plan; and
  • Set personal priorities to ensure attention to all communications and attendance at all BOD meetings.

For more information about the Board of Directors (BOD) please see the Policy and Procedure Manual

COUNCIL ON MICROBIAL SCIENCES (COMS)

The Society's scientific affairs shall be conducted through the Council on Microbial Sciences (COMS), which advises the BOD on scientific matters coming before the COMS and from other groups within the Society.

Functions. The COMS serves six main functions:

  • Is the “creative mind” of the Society that generates and deliberates on microbial sciences - related ideas, issues, and programs. The COMS has its radar screen set to scan the horizon to detect and anticipate trends in the science
  • Informs and advise s the BOD on scientific opportunities and threats , suggesting policies, actions , and programs that need to be taken or initiated to advance the microbial sciences
  • Works in partnership with the BOD and seeks BOD approval for resources for scientific programmatic activities deemed a priority by the COMS
  • Works in partnership with BOD , CEO , and staff to explore feasibility and implementation of programs
  • Identifies and makes recommendations to the BOD for discontinuation of scientific programs deemed no longer essential for the future of microbial sciences
  • Considers petitions to charter Branches and Divisions/SIGs at the programmatic level, and submit s to the BOD for fiduciary review and approval

Six broadly defined characteristics of an exceptional COMS to be considered include, but are not limited to:

  • Is broadly representative of the microbial sciences and the various components of the Society in all its scientific, ethnic, gender, cultural, and geographical components
  • Is composed of elected members who are recognized for their scientific and professional achievements and are leaders in their profession
  • Is visionary regarding the future of microbial sciences and speaks authoritatively
  • Is focused on the long-term horizon of the science, professional practice, and educational affairs
  • Works in partnership with the BOD, CEO, and staff to ensure that ASM allocates attention and resources to anticipate opportunities which will grow and advance the microbial sciences
  • Works in partnership with committees and staff to ensure the feasibility and implementation of proposed programs

Committees of the COMS will be generated and populated by processes identified in policies and procedures established by the COMS itself. The COMS shall adopt, and may amend from time to time, policies and procedures in the scientific interest of the Society, provided that such policies and procedures shall not be inconsistent with the Articles of Incorporation, Bylaws, or Policy and Procedures Manual of the Society. The COMS shall publish and make generally available to the membership any such policies and procedures in effect at any time.

For more information about the Council on Microbial Sciences (COMS) please see the Policy and Procedure Manual

Thank You for Volunteering

 

Thank you for volunteering to serve as a speaker for ASM's Speakers Bureau. The information you submitted will be added to the online profile of speakers. ASM staff will contact you in the coming months with additional information. If you have any questions or concerns, please email professionalpractice@asmusa.org.

 

2017 Election Position Descriptions

President-Elect    Secretary    BOD At-Large Representatives    COMS At-Large Representatives

 

 

PRESIDENT-ELECT

The President-Elect provides secondary leadership for the Society, substitutes for the President when needed, and prepares to serve as President. The President-Elect shall assist the President, shall be a voting member of the BOD and an ex officio, nonvoting member of the COMS, and  shall substitute for the President in the absence of the President. The President-Elect shall take precedence over the Past President in substituting for the President.

Other roles of the President-Elect include:

  • Review the performance of the various BOD Standing Committee and Program Board/Committee Chairs.
  • Chair the Appointments Committee.
  • Chair, if requested by the BOD, an ad hoc committee to review a major activity, function, or program of the Society or profession and provide a written report with specific recommendations to the BOD.

SECRETARY

The Secretary shall assist the President and shall be responsible for overseeing the accuracy of the minutes of all meetings of the BOD and meetings of the Membership.

In addition, the Secretary shall:
•    Provide continuity of service and experience among the Officers.
•    Work closely with the CEO to ensure timely appointment of volunteer members of the organization.
•    In collaboration with the CEO, ensure transmittal to ASM Archives of documents of archival or historical value.

AT-LARGE POSITIONS FOR THE ASM BOARD OF DIRECTORS (BOD)
Main Functions

Members of the Board of Directors have the primary fiduciary responsibility for governance and the exercise and assignment of power of authority for the Society. It is the highest governing body of the Society which oversees all other bodies and functions. The Board of Directors (BOD) functions include:

  • Setting the strategic direction and upholding the objectives of the Society
  • Authorizing policy matters
  • Directing fiduciary, legal, and business decisions
  • Hiring and overseeing the work of the CEO
  • Upholding the strategies and measuring progress through objectives
  • Ensuring that the Society’s property, funds, and affairs are handled in conformity with the Bylaws and within the Articles of Incorporation of the Society under the statutes of the District of Columbia (D.C.)
  • Approving an annual budget

The BOD delegates to the Council on Microbial Sciences (COMS) the role of identifying trends in science and suggesting programs that best capture and serve the future of microbial sciences and its workforce, and reserves for itself the role of approving them. The BOD delegates to the CEO responsibility for leading and managing operations. The BOD does not operate as an “outside examiner” of the Society; rather, it supports the roles of the COMS, Program Boards/Committees, CEO and staff in a constructive partnership. The role of the BOD is to govern, the role of the COMS is to exercise oversight over scientific and programmatic activities; the CEO is responsible for implementation and operations.
Directors are responsible, in partnership with other Board members and staff, for helping to shape and lead ASM to promote and advance microbial sciences. They accomplish their function by participating actively in Board meetings, guiding and overseeing the ASM strategic plan, and by performing fiduciary, strategic, and policy responsibilities.

Term
At-Large BOD members serve three year terms, and can be reelected only once. Just for elections in 2017, in order to stagger terms of various members, a cohort of Directors will serve a one-year term, another cohort a two-year term, and the third cohort a three-year term.

Time Commitment
Directors are expected to attend all in-person meetings and phone calls. It is expected that the BOD will normally meet three times a year, twice in person for 1.5 days and once for half a day electronically. One of the in-person meetings will be in conjunction with the ASM Microbe meeting. 

BOD members are expected to read the provided background material in advance and actively participate in meetings and calls. More calls could be scheduled throughout the year, if needed. BOD members are expected to participate in ASM Microbe meeting and other working groups or events that may require Directors’ presence. In total it is expected a time commitment of ~ 9-10 days per year. This job requires a level of awareness of ASM as an organization and responsiveness to ongoing Board work.


Responsibilities

  • Set direction for ASM, after considering input from the Council of Microbial Sciences (COMS)
  • Establish the vision, mission, and strategic plan of ASM. Oversee the execution of the strategic direction of ASM
  • Articulate, safeguard, model, and promote ASM’s core values and principles
  • Act in the best interests of the organization as a whole, not for any individual, particular constituencies or sub-discipline
  • Delegate authority for organizational and staff management to the CEO
  • Provide oversight and ensure resources
  • Be knowledgeable about the bylaws, policies and procedures, strategic plan, and governance responsibilities of the ASM BOD
  • Establish financial policies and ensure accountability
  • Ensure resource allocation is aligned with the ASM strategic plan
  • Ensure compliance with applicable laws and ethical standards
  • Receive and examine an annual audit of ASM by an independent auditor
  • Approve an annual budget and review performance of the annual operating plan and budget
  • Hire, support and evaluate the CEO
  • Serve as an ambassador for ASM to promote and advance microbial sciences, by promoting ASM and encouraging others to get involved in volunteering at ASM
  • Utilize and respect staff expertise
  • Prepare for, attend, and actively participate in all Board of Directors meetings
  • Work collegially with other Board members and key staff by “holding their own” feeling safe to disagree without being disagreeable
  • Understand that the BOD is not a stakeholder group, rather a governing body, therefore, once a decision is made, it is the decision of the whole group
  • Know when and how to present views on policy or issues, knowing that the BOD needs to function as a group that makes decisions and is not simply a discussion forum
  • Understand and apply the provisions of fiduciary responsibility, the bylaws and other policies
  • Abide by the code of conduct and conflict of interest policies
  • Function at a strategic, not tactical, level
  • Participate in periodic evaluation of the Board’s performance and contribute to ongoing improvement of ASM governance
    Participate in Board orientation and be knowledge about effective governance


 

AT-LARGE REPRESENTATIVE TO THE COUNCIL ON MICROBIAL SCIENCES (COMS)

Main Functions

The ASM Council on Microbial Sciences At-Large members advance ASM and microbial sciences by scanning the environment and advising the Board of Directors (BOD) on scientific and programmatic matters. COMS members bring a key perspective which represents the diversity of microbial sciences and demographics that exist within ASM. The COMS partners with the BOD and staff to shape and lead ASM and microbial sciences into the future.

COMS has several key distinctive functions:

  • Is the “creative mind” of the Society that generates and deliberates on microbial sciences-related ideas, issues, and programs.
  • The COMS has its radar screen set to scan the horizon to detect and anticipate trends in the field Informs and advises the BOD on scientific opportunities and threats, suggesting policies, actions, and programs that need to be taken or initiated to advance the microbial sciences
  • Works in partnership with the BOD staff and seeks BOD approval for resources for scientific programmatic activities deemed a priority by the COMS
  • Works in partnership with BOD and staff to explore feasibility and implementation of programs Identifies and makes recommendations to the BOD for discontinuation of scientific programs deemed no longer essential for the future of microbial sciences
  • Considers petitions to charter Branches and Divisions/SIGs at the programmatic level, and submits to the BOD for fiduciary review and approval

Terms

At-Large Councilors are elected for a three-year term, renewable once. For elections in 2017 only, to generate staggered terms, there will be three cohorts of At-Large members serving respectively one, two, and three year terms.

  •  Time Commitment

    At-Large members of COMS are required to attend one day-long in-person meeting, held in conjunction with the ASM Microbe meeting. In addition, working groups and task forces of COMS will meet electronically throughout the year, possibly 3-4 times for a few hours each time. Full participation requires reading background material in advance and collegial discussions and active work. This job requires a level of awareness of ASM strategic plan, activities, and responsiveness.

     Roles and Responsibilities:

    • Advise the BOD and support ASM mission Maintain awareness of emerging issues that could impact microbial sciences
    • Oversee and propose scientific and programmatic activities to advance microbial sciences through ASM activities
    • Understand and act within the financial and strategic framework set by the BOD
    • Engage members
    • Advance the vision, mission, and strategic plan of ASM
    • Bring a unique perspective within microbial sciences, keeping in mind your responsibility to act in the best interests of the organization, not of yourself, nor of any particular constituency
    • Build relationships internally and externally
    • Champion ASM and microbial sciences to all constituents and publics
    • Ensure good interaction with other components of the Society
    • Act as an ASM ambassador, encouraging others to get involved in volunteering at ASM
    • Utilize staff expertise
    • Get to know other COMS members and key staff
    • Be an active member of the COMS
    • Prepare for, attend, and actively participate in all COMS meetings
    • Be knowledgeable about the ASM bylaws, policies and procedures, strategic plan, and governance responsibilities of the COMS
    • Abide by the code of conduct and conflict of interest policies
    • Function at a strategic, not tactical or operational level
    • Be cognizant that the authority rests with the COMS as a collective body, not to any one individual member, or group of members
    • Participate in COMS orientation and be knowledgeable about effective governance

    Starving Yourself Just Might Let You Live Longer and Healthier

    While it is generally thought that bacteria are bad for us, research has shown that bacteria are important in our health and possibly longevity. Bacteria inhabit just about every part of the human body ranging from the skin, nose and the intestinal tract. In fact, bacteria make up more cells in the body than human cells and are collectively known as the microbiome. The microbiome of the intestine has been shown to play a role in disease such as obesity and diabetes. The intestinal microbiota has also been linked to a variety of beneficial functions that include the breakdown of nutrients, vitamin production and development of the immune system. For over 50 years, research has shown that reducing the amount of food an animal consumes (a process known as calorie restriction, CR) increases lifespan by retarding aging because most age-related diseases are delayed or reduced by CR.  Because diet and age can exert major effects on the composition of the intestinal microbiota, we hypothesized that CR, specifically 40% restriction, would delay/prevent age related changes in the intestinal microbiota.


    Researchers from the University of Oklahoma Health Sciences Center (OUHSC) and the Missouri Mutant Mouse Resource and Research Center (MU MMRRC) studied the effect of age and life-long CR on the composition of the intestinal microbiota of young and old laboratory mice. The results will be presented at the ASM Microbe in Boston, Massachusetts on Saturday June 18, 2016.


    As mice age, significant changes in the composition of the microbiota were observed. For example, there was a decrease or absence of specific bacteria in the old mice that were present in the young mice.  Conversely, there were also bacteria that were found in the old mice but not in the young mice. In addition to the changes described above, overall, there was about a 30% reduction in the number of different types of bacteria found in the old mice compared to the young mice.


    CR altered the overall composition of the intestinal microbiota of old mice in comparison to their old counterparts that were given unlimited access to food. The old calorie restricted mice contained a microbiome profile that was highly similar to that found in the young mice.  Additionally, with the old calorie restricted mice there were no age-related reductions in the number of different types of bacteria and were comparable to that of the young mice.


    From this study, researchers were able to demonstrate for the first time that CR prevented the age-related changes in the intestinal microbiome. The implications of this data suggests that the preservation of the young intestinal microbiota profile found within old CR mice may play a role in the prevention or delay of age-related diseases as well as the extension in lifespan seen with CR.  Additional research will be needed to determine if these differences in the microbiome are beneficial or harmful as well as determine whether or not these changes play a role in the extension of lifespan.


    This study will be presented on at the American Society for Microbiology’s Microbe 2016 meeting in Boston, MA.

    ASM 2017 Election

     

    ASM Governance

     

     

     

     

     

     

     

     

     

     

    ASM Governance Change Banner 2
     

    ASM 2017 ELECTION IS NOW OPEN!  VOTE HERE [INSERT LINK TO VOTING SITE]

     

    Strategic Plan simple

    It is with great excitement that we approach the new ASM governance.  One of the most important steps is that of filling the At-Lavote microberge positions for both the Board of Directors (BOD) and the Council on Microbial Sciences (COMS). This is a unique opportunity for ASM members to get involved in leadership positions.

     

     

    Briefly, the BOD is the governance body that sets the course for the whole Society by fulfilling all fiduciary roles, including approval of the budget.  

    The COMS will be the main advisory body to the BOD and will make recommendations for the strategic, scientific, and programmatic direction of the Society. Both bodies will serve key roles in the microbial sciences by providing leadership and direction to the Society and to the whole field.

    It is worth noticing that there will be one slot on the BOD and one slot on COMS for a young microbial scientist, someone who is at the level of Graduate Student, Postdoc, Assistant Professor, or junior clinical microbiologist or equivalent.  There will also be one slot on the BOD, and two slots on COMS, for members working outside of the US.

     FAQS - either drop down list of questions or link to another page

     

    What is the ASM Board of Directors? Summary

     What is the Council on Microbial Sciences?  Summary

    What are the position descriptions?

     

    If you have any questions, please reach out to Ms. Cheryl Lehr clehr@asmusa.org in the Office of the ASM CEO.

    Sincerely,  

    Susie Sharp
    Susan Sharp
    President
    Tim Donohue SignatureVer2
    Timothy Donohue
    Secretary
    StefanoBertuzzi
    Stefano Bertuzzi
    CEO

     

     

     

     

     
     
     
     

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    Image Gallery

     

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    Contaminated Gloves Increase Risks of Cross-Transmission of Healthcare-Associated Pathogens
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    legionella strains

    Ongoing Monitoring of Legionella in Flint in the Wake of the Drinking Water Crisis
    Dr. Otto Schwake

    Eight strains of Legionella isolated from a health care center in Flint, MI during March 2016.  Photograph: Otto Schwake

     

     

     

     

     

     

     

     

    water bottlesSamples of discolored tap water and a rusty water filter provided by Flint residents.
    Photograph: Virgina Tech/Jim Stroup

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    S.mutans colony morphology

    Sharing of Tooth Decay Causing Bacterium Among Children and Their Families
    Stephanie Momeni

    S. mutans colony morphology

     

     

     

     

     

     

     

     

     

     

    SEM.K904 on Bleb.pseudo.copyResearch Shows New Mechanism That Can Cause Eye Inflammation
    Dr. Robert Shanks

    Pseudo-colored electron micrograph of Serratia marcescens bacteria (red) on a human corneal cell in vitro.  The yellow arrow indicates a large surface bleb induced by a toxin produced by the bacteria.  The white bar indicates 10 microns.

     

     

     

     

     

     

     

     

    A Novel Therapy for Genital Herpes Engages Immune Cells to Provide Significant Patient Benefits for at Least a Year
    Dr. Kenneth Fife, MD, PhD, investigator and Professor of Medicine at Indiana University

     

     

     

     

     

     

     

     

     Genociarevised

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    Pisciotta1Photo: WCU Researchers: From left to right. Dr. John Pisciotta, graduate student Paige Minka and undergraduate Jeremy Irving prepare to install sMFCs in Paradise Farms pond (Downingtown, PA).

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    muddy microbesFig. 1:  sMFC components and experimental installation plan depict two sMFCs with identical sediment-buried graphite anodes wired (in red) to transmit microbially-generated electric current from anodes to an upper cellular data relay unit (upper box) that transmits the data from the field site. Electrons then pass via wires (green) to carbon cloth cathodes (grey ovals) suspended in the water at variable depths. Leftmost sMFC features a surface cathode while the sMFC at right has a submerged cathode. Identical replicate sMFCs (not shown) were included in the study.

    Take Advantage of These ASM Resources

    ASMLogo    

    Step 1: Register for ASM Microbe 2017

    Join your peers from around the world to explore the complete scope of microbiology – from basic science to translational and clinical application – at ASM Microbe 2017 (June 1–5, 2017, New Orleans, Louisiana). The special Infectious Diseases Fellows Program offers an opportunity for you to attend the meeting free of charge.

    >> View the program.

    >> Register before April 20 for the special rates.

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    Step 2: Listen to the ASM-CLSI Webinar Series


    Register for the ASM-CLSI Webinar Series in Antimicrobial Susceptibility Testing: Fundamentals of Susceptibility Testing, Reporting, and Test Validation to learn the fundamentals for AST in the clinical microbiology laboratory. Registration includes access to the live webinars, the recorded presentation, and P.A.C.E.® or Florida continuing education credits.

    >> Register for the webinar now.

     

    ASM3


    Step 3: Join ASM

    Join the world’s largest life science society that works for you.  Enrich your network with ASM’s clinical microbiology listserv, pursue career opportunities with ASM’s career website, and obtain discounts* on public health-related books, journals, and conferences!  Membership starts at $22. 

    >> Become an ASM member now.

    * Discounts do not apply to all membership categories.

    Thank you for your RSVP

    Thank you for your RSVP to the ASM Officers' Reception.

     

    Saturday, June 18th from 7:30 pm to 9:00 pm

    The Westin Boston Waterfront


    Grand Ballrooms BCDE (Concourse Level)


    425 Summer Street


    Boston, MA

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    Thank you for your RSVP

    Thank you for your RSVP to the Division Officers Forum.

    The meeting will be held on Thursday, June 16th from 8:30 - noon at
    The Westin Boston Waterfront
    Grand Ballrooms C
    425 Summer Street
    Boston, MA

    A continental breakfast will be served.

    Journals Reception Sign Up

     

     

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    Sign up to keep up-to-date with microbial sciences

     

     

    Register for ASMCUE by May 16 and Save $100!

    Stop what you're doing right now and take advantage of our Early Registration prices!  Receive discounted rates to attend ASMCUE, including special registration rate for Grad Students and Postdocs. While registering, attendees have the option to support a colleague’s attendance to the conference by making a donation to the ASMCUE travel grant fund. Fees will increase after May 16.

    Register here: http://bit.ly/asmcueearlyregwn

    Membership for Clinical Microbiologists

    JOIN OR RENEW TODAY

     

    “Who is looking out for the interests of clinical microbiologists? In my view, the American Society for Microbiology is doing this exceedingly well.”

    Joseph Campos, PhD, D(ABMM), FAAM
    Director of the Microbiology Laboratory at Children’s National Medical Center

    ASM understands the vital importance clinical microbiology plays in sustaining the health of the world population. We know the daily challenges that you face in the prevention, diagnosis, and treatment of infectious disease. ASM supports the clinical microbiological community in many unique ways – with cutting-edge information, professional certification and awards, and a robust advocacy for the field. Here is how we can help you…


    Access to cutting-edge information through:

    • ASM’s Microbe 2017 meeting, combining the dedicated clinical track of the former General Meeting with the premier infectious disease offerings of ICAAC
    • ASM Journals – seven journals devoted to clinical microbiology and immunology that delivers authoritative and high-quality clinical research
    • CUMITECH lab references – now free with membership!
    • Clinical Microbiology Portal – access to a database of over 1,500 expertly answered questions, and more
    • Two vibrant listservs dedicated to current clinical issues
    • NEW MEMBER TYPE:  CLS/MT/MLT Labtech Membership with up to 12 CE credits

     

    Certify your accomplishment and expertise through:

    • Certification by the American Board of Medical Microbiology (ABMM), the American Board of Medical Laboratory Immunology (ABMLI), and the National Registry of Certified Microbiologists (NRCM)
    • ASM’s Continuing Education (CE) Portal – the online source for accessing and tracking all continuing education activities
    • Awards and recognition specifi cally focused on clinical microbiologists including the BD Award for Research in Clinical Microbiology, Scherago-Rubin Award, and the Beckman-Coulter Young Investigator Award


    Advocacy for the interests of the clinical community through:

    • Encouraging the adoption of sound policies
    • Monitoring federal legislation and regulation
    • Communicating microbiological issues to the public
    • Participating in CDC/APHL organized meetings

    JOIN OR RENEW TODAY

    ASM Branches Listening Tour

    ASM Branches Listening Tour


    Dear ASM Branch member,

    I'm on my way to see you. During 2016, I will be on the road for the first ever listening tour of the ASM Branches. I intend to visit in person all 36 ASM Branches in the United States. Actually I've already started. On the first weekend in April, I set out on the first of what will be a series of mostly weekend flying visits, dropping in on ASM Branches and meeting the members in their natural professional habitats.

    When I became CEO of the ASM in January, I resolved to test what has been one of my core principles-I was going to listen to ASM members. Visiting all 47,000 ASM members at home seemed a little ambitious, but visiting all 35 branches could give me an incredible overview of part of the organization that is vital to our collective community. I know that once you have visited one ASM Branch, you have seen only that one branch, because they are as diverse as microbial sciences are. So I plan to see all 36 branches.

    I want to hear firsthand what the branches need, what they cannot easily find elsewhere, and what they hope ASM Central can do for them. I also want to share the vision for the future of ASM as an organization and to communicate directly about the changes already underway at Headquarters and what changes are to come. It is also a great opportunity for making new friends and having a good time together.

    feedbakEqually important to me is the chance to forge personal relationships with so many working microbiologists. During my first two visits, at the Indiana and Rio Grande Branches, I heard exciting stories of scientific discovery and of professional growth. For example, I met Indiana University SouthEast senior Tyler Mercer who is looking for ways to stay in the lab after he graduates. Tyler has become mesmerized by phages and by science in general, but he comes from a family background where there was not much support for studying science. It occurred to me that ASM has made a crucial difference for Tyler. Not only did ASM members show Tyler ways to pursue microbial science, but the very existence of the Indiana ASM Branch reassured him that there are other people who care a great deal about phages and that these people make a good living and have a great career by putting their curiosity and knowledge to work. I left Fort Wayne thinking that this is exactly why we are in business as an association. We are here to make members better off because of their involvement with ASM.

    So the ASM Branches listening tour is off to a flying start. On this page you can see my future itinerary and stops so far. I will also post simple videos and photos I take during my visits. Stay tuned, and feel free to connect. As I will tweet about my Branch visits, follow me on Twitter @sutefune or just email me ceo@asmusa.org. If your ASM Branch is not yet on my schedule, feel free to reach out so that we can meet!

    Onward and forward, ASM Branches!

    Sincerely,
    Stefano

     

    BRANCH VISITS AND DATES

    April 1-2, 2016 Indiana Branch ASM Meeting April 2016
    April 1-2, 2016
    Rio Grande Branch ASM Meeting April 2016
    April 9, 2016 -
     Rocky Mountain Branch ASM 2016 Spring Meeting
    April 14, 2016
    Washington DC Branch ASM Joint Meeting with George Mason University Student Chapter ASM April 2016
    April 20 2016 -
    Northeast Branch ASM Spring Meeting
    April 22-23, 2016
    Michigan Branch ASM 2016 Spring Meeting
    April 23, 2016 - 
    Intermountain Branch ASM 2016 Meeting 
    April 25, 2016
    - Eastern Pennsylvania Branch
    April 29, 2016
    - Virginia Branch
    May 10-11, 2016
    Illinois Branch ASM (IL Society For Microbiology) 2016 Spring Meeting 
    May 26, 2016
    - Puerto Rico Branch
    October 27-29, 2016
    Southern California Branch 80th Annual Meeting



    VIDEOS AND PHOTOS FROM THE TOUR

    Indiana Branch - Fort Wayne, IN

    Tim Donohue
    ASM Past President Tim Donohue
    John McKillip
    John McKillip speaks about science education
    Ellen Wagner
    Ellen Wagner, Ball State University
    Tanya Soule
    Tanya Soule organizer of the ASM Indiana Branch meeting
    Tyler Ulysses Mercer
    Tyler Ulysses Mercer


    Rio Grande Branch - El Paso, TX

    Charles Spencer
    Dr. Charles Spencer, President of the ASM Rio Grande Branch

     

    ROCKY MOUNTAIN BRANCH - DENVER, CO

    Rocky Mountain Branch

     

    WASHINGTON, DC BRANCH - FAIRFAX, VA

    dc-branch

     


    MICHIGAN BRANCH - GRAND RAPIDS, MI

    Anne Spain
    Anne Spain, President of the ASM Michigan Branch
    Susan Dunn
    Susan Dunn, Dean of Davenport University, host of the spring Michigan Branch meeting

     

    INTERMOUNTAIN BRANCH - SALT LAKE CITY, UT

    Justin Nielsen and Luke Goldston
    Justin Nielsen and Luke Goldston, Utah State University Eastern discuss their work with Small World Initiative
    Professor Wayne Hatch
    Professor Wayne Hatch, Utah State University Eastern, Small World Initiative
    Eli Cohen
    Eli Cohen explains his research on the assembly of flagella in Salmonella
    Matt Mulvey
    Matt Mulvey, President of the ASM Intermountain Branch

     

    Clinical Microbiologists

    “Who is looking out for the interests of clinical microbiologists? In my view, the American Society for Microbiology is doing this exceedingly well.”

    Joseph Campos, PhD, D(ABMM), FAAM
    Director of the Microbiology Laboratory at Children’s National Medical Center

    ASM understands the vital importance clinical microbiology plays in sustaining the health of the
    world population. We know the daily challenges that you face in the prevention, diagnosis, and
    treatment of infectious disease. ASM supports the clinical microbiological community in many
    unique ways – with cutting-edge information, professional certifi cation and awards, and a robust advocacy for the field. Here is how we can help you…


    Access to cutting-edge information through:
    • ASM’s Microbe 2017 meeting, combining the dedicated clinical track of the former General Meeting with the premier infectious disease offerings of ICAAC
    • ASM Journals – seven journals devoted to clinical microbiology and immunology that delivers authoritative and high-quality clinical research
    • CUMITECH lab references – now free with membership!
    • Clinical Microbiology Portal – access to a database of over 1,500 expertly answered questions, and more
    • Two vibrant listservs dedicated to current clinical issues
    •  NEW MEMBER TYPE:  CLS/MT/MLT Labtech Membership with up to 12 CE credits

    Certify your accomplishment and expertise through:
    • Certifi cation by the American Board of Medical Microbiology (ABMM), the American Board of Medical Laboratory Immunology (ABMLI), and the National Registry of Certifi ed Microbiologists (NRCM)
    • ASM’s Continuing Education (CE) Portal – the online source for accessing and tracking all continuing education activities
    • Awards and recognition specifi cally focused on clinical microbiologists including the BD Award for Research in Clinical Microbiology, Scherago-Rubin Award, and the Beckman-Coulter Young Investigator Award

    Advocacy for the interests of the clinical community through:
    • Encouraging the adoption of sound policies
    • Monitoring federal legislation and regulation
    • Communicating microbiological issues to the public
    • Participating in CDC/APHL organized meetings

    JOIN OR RENEW TODAY

    bertuzzi-bio

    Hello bLogPhase reader,

    I am Stefano Bertuzzi, the Chief Executive Officer of the American Society for Microbiology (ASM). I use bLogPhase to communicate my thoughts with ASM members as well as anyone interested in science and various policy issues related to science. Before joining ASM, I blogged for ASCB on similar topics.

    I have a Ph.D. in Molecular Biology from the Universita' Cattolica del Sacro Cuore of Milan, Italy, and a Master's degree in Public Health from Johns Hopkins University. As a student, postdoc and PI, I was a bench researcher in the U.S. and Italy for 15 years before moving over to the science policy side at NIH in 2006. I have enjoyed every step of my scientific career and coming to the world of scientific associations has opened even wider horizons for me on what a scientist can do in modern society.

    I've always liked to write. For a brief time, I had a fling considering writing as a career, and even became a registered journalist in my native Italy. But research science won out. But now, with bLogPhase I am looking at a new part time career as a blogger. As excited as I am about writing bLogPhase I realize that a blog has to be a two-way street. This blog needs your comments, corrections, additional thoughts, push back and, I hope, an occasional "Bravo." (Well, at least no rotten tomatoes.) So post your comments and your ideas. This is a space for ASM members and all those interested in the microbial sciences, science policy and science communications to interact.

    Before joining ASM, I was the Executive Director of the American Society for Cell Biology (ASCB) and previously the Science Policy Director at the National Institute of Mental Health (NIMH) where I greatly enjoyed working with Tom Insel, an extraordinary scientist and advocate for research into mental disorders. Before NIMH, I was in the Office of the NIH Director, in charge of the Return on Investment Program. There, I worked with Lana Skirboll, Lynn Hudson, and Elias Zerhouni. I am indebted to all of them for infusing me with an incurable passion for public service and science policy.

    My wife, Elena, and I have been together since high school. We have two young children, Davide and Celeste. I love being on the water, sailing or windsurfing. I am an avid reader as regular readers of bLogPhase will soon discover.

    So follow me and please jump in with your comments.

    Multisociety Transition Letter

    November 23, 2016

    Mr. Donald Trump
    Office of President-Elect
    1800 F Street, NW
    Washington, DC 20006

    Dear President-elect Trump:

    On behalf of the U.S. scientific, engineering, and higher education community we are looking forward to working with you, as 45th President of the United States, and your administration.

    As President you will face a wide range of domestic and international challenges, from protecting national and energy security, to ensuring U.S. economic competitiveness, curing diseases, and responding to natural disasters. These challenges share one thing in common: the need for scientific knowledge and technological expertise to address them successfully.

    For this reason, we urge that you quickly appoint a science advisor with the title of Assistant to the President for Science and Technology who is a nationally respected leader with the appropriate engineering, scientific, management and policy skills necessary for this critically important role. This senior level advisor can assist you in determining effective ways to use science and technology to address major national challenges. Moreover, this individual can coordinate relevant science and technology policy and personnel decisions within the executive branch of government.

    The economic benefits of advancements in science, technology and innovation have been well documented, estimated by leading economists to have accounted for approximately half of U.S. economic growth over the last fifty years. Past government investments in the U.S. scientific and technological enterprise have fueled our economy, created new jobs, and ensured our global competitiveness and national security. At the same time, these investments have enabled the development of a system of U.S. research universities and national laboratories unmatched in the world.

    We know that one of your top priorities will be to focus on ensuring that the U.S. economy remains strong and continues to grow. If we are to maintain America’s global leadership, and respond to the economic and security challenges currently facing the nation, we must build on our strong history of federal support for innovation, entrepreneurship and science and technology.

    Toward that end we would appreciate the opportunity to meet with you or leaders of your transition team to discuss how the science and engineering community can assist with developing a path forward to ensure that the U.S. innovation infrastructure grows and flourishes under your administration and to suggest candidates for top science and technology posts.

    Thank you for your consideration and we look forward to your response. You may contact Joanne Carney (jcarney@aaas.org) with the American Association for the Advancement of Science (AAAS) to coordinate a convenient meeting time, and we will follow up with a proposed list of attendees.

    Rush D. Holt
    Chief Executive Officer
    American Association for the Advancement of Science

    Kevin B. Marvel
    Executive Officer
    American Astronomical Society

    Donna J. Nelson
    President
    American Chemical Society

    Chris McEntee
    Executive Director and CEO
    American Geophysical Union

    Milan P. Yager
    Executive Director
    American Institute for Medical and Biological Engineering

    Robert G.W. Brown
    Chief Executive Officer
    American Institute of Physics

    Kate P. Kirby
    Chief Executive Officer
    American Physical Society

    Martin Frank
    Executive Director
    American Physiological Society

    Stefano Bertuzzi
    Chief Executive Officer
    American Society for Microbiology (ASM)

    Crispin Taylor
    Chief Executive Officer
    American Society of Plant Biologists

    Nancy Kidd
    Executive Officer
    American Sociological Association

    Robert H. Rich
    Executive Director
    Arctic Research Consortium of the United States (ARCUS)

    Thomas G. Loughlin
    Executive Director
    ASME

    Sarah Brookhart
    Executive Director
    Association for Psychological Science

    Mary Sue Coleman
    President
    Association of American Universities

    Peter McPherson
    President
    Association of Public and Land-grant Universities

    Keith Yamamoto
    Chair
    Coalition for the Life Sciences

    RADM Jonathan White (ret., USN)
    President and CEO
    Consortium for Ocean Leadership

    Wendy A. Naus
    Executive Director
    Consortium of Social Science Associations

    Madeleine Jacobs
    President and CEO
    Council of Scientific Society Presidents

    David M. Lodge
    President
    Ecological Society of America

    Howard H. Garrison
    Deputy Executive Director for Policy
    Federation of American Societies for Experimental Biology

    Shirley M. Tilghman
    Co-founder
    Rescuing Biomedical Research

    Mary Woolley
    President
    Research!America

    John C. Nemeth.
    Executive Director and CEO
    SIGMA Xi, The Scientific Research Society

    Thomas Grumbly
    President
    SoAR Foundation

    Marty Saggese
    Executive Director
    Society for Neuroscience

    Peter Walter
    President
    The American Society for Cell Biology

    Elizabeth A. Rogan
    Chief Executive Officer
    The Optical Society (OSA)

     


    Vincent Racaniello 300

    Hello everyone,

    I am Vincent Racaniello, Higgins Professor of Microbiology & Immunology at Columbia University College of Physicians and Surgeons. I am using Zika Diaries to communicate the experiences of my laboratory as it moves from working on poliovirus (for 35 years) to Zika virus.

    I was fortunate to be trained in virology by two brilliant virologists. I obtained my Ph.D. with Peter Palese at Mt. Sinai School of Medicine in New York City. As his first student, I received a great deal of attention as I worked on influenza viruses. For my postdoctoral work I was lucky to work with David Baltimore, just a few years after he received his Nobel Prize. In his laboratory at MIT I produced the first infectious DNA copy of an animal virus, a finding that revolutionized the study of viruses. I moved to Columbia in 1982 to start my own laboratory. Over the years our main focus has been on poliovirus.

    Halfway into my research career, I developed an interest in science communication. I became part of the team that produced the ASM textbook 'Principles of Virology' in 2000. Having learned about all viruses (not just poliovirus), I wanted to share this knowledge with the public. Blogging had just become much easier, so in 2004 I started writing at virology blog (virology.ws), which I continue to this day. I also produce, with ASM, a suite of science podcasts, including the flagship This Week in Virology (microbe.tv). When I decided to teach an undergraduate virology course at Columbia University, I recorded all my lectures and released them at YouTube. All of these efforts are enhanced by the ability to reach millions via Twitter, Facebook, and other internet based technologies. You know where to find me - just google me.

    Despite all this fun and fascinating activity, I jumped at the opportunity to write a new blog for ASM. Zika virus moved into world view in 2015 and many virologists, including myself, have moved to work on this important virus. I thought it would be illuminating to provide a weekly, personal view of our success and failures. All centered on an image from my laboratory (yes, I’m also at Instagram.com/profvrr).

    Questions and comments are always welcome.

    TPL_asm2013_SEARCH

    governance2