zika

Funding Alert: Contact Congress for Emergency Funding for Zika

Please contact Congress to urge the immediate passage of a bipartisan emergency supplemental bill for Zika.
Take Action

ASM Acts to Counter Zika Virus Outbreak

The emerging threat of Zika virus infection.
Read

ASM Urges Action to Combat Zika Emergency

Current events linked to the Zika virus make aggressive public health actions and funding to combat this emerging infectious disease more crucial than ever.
Read
New Governance Information
VOTE
Become a member today!
JOIN ASM
Submit Abstracts for ABRCMS
SUBMIT
Register for ABRCMS
REGISTER

baric ralph

 

The Baric laboratory uses genetic, immunologic and biochemical approaches to study the molecular mechanisms regulating viral replication, pathogenesis, evolution, virus-host interactions and cross species transmission using coronaviruses and noroviruses as model systems. They also deconstruct the fundamental viral/host genetic and pathogenic pathways that modulate virulence in vivo using young and aged models of human disease. One outcome is to harness unique biological processes encoded in viral genomes as tools for developing safe efficacious vaccines and/or vector platforms for the treatment of human diseases. Laboratory expertise includes virus reverse genetic approaches for several positive strand RNA viruses, phylogenetic and structural modeling of virus-receptor interactions, functional genomics and next gen sequencing, and evolutionary genetic approaches to understand virus persistence and pathogenic mechanisms in human populations. The laboratory has a particular interest and tract record in using synthetic genomics to manipulate viral genomes and reconstruct noncultivatable viruses from in silica sequence information sources, including the synthetic reconstruction of the largest RNA virus genome to date from in silica sequence signatures; a platform to ask fundamental questions into virus emergence and disease.

TPL_asm2013_SEARCH

91001