AMR Sept Banner

ASM Attends UN General Assembly

ASM President, Susan Sharp, Ph.D., joined global leaders at the United Nations General Assembly in New York today in a historical meeting to focus on the commitment to fight AMR.
Read

UN General Assembly Focuses on AMR

Leaders at the UN General Assembly draft a plan for coordinated, cross-cutting efforts to improve the current state of AMR.
Read

Superbugs are a 'Fundamental Threat'

If antibiotics were telephones, we would still be calling each other using clunky rotary dials and copper lines," Stefano Bertuzzi, CEO of ASM, told NBC News.
Read
Become a member today!
JOIN ASM
Submit Abstracts for Biothreats 2017
SUBMIT
Antibacterial Development Conference
REGISTER

sparling fredDr. Sparling’s early work helped define the genetics of antimicrobial resistance in the gonococcus, and the mechanisms of genetic transformation and of plasmid transfer in the gonococcus. Subsequent work focused on the genetics of the outer membrane of gonococci, with emphasis on the porin protein and of the several iron-regulated receptors for binding and transporting iron and heme from sources available in humans. Studies in male human volunteers established that either the transferrin or lactoferrin receptor was essential for initiating infection in the urethra, and that expression of both receptors provided a competitive advantage compared to expression of only the transferin receptor. Other studies focused on the function of genes in the TonB family; of the secretin PilQ; and of the importance of LOS structure to serum resistance. Current studies with his colleagues are focused on the roles of PilC in adherence, and the possibility of constructing a vaccine to prevent gonorrhea. Recent work showed the importance of a vigorous innate and/or Th1 response in protecting female mice from genital gonorrhea. Currently he is PI and director of the SE Regional Center of Excellence in Biodefense and Emerging Infections (SERCEB), and also of the SE STI Cooperative Research Center, both based at UNC but regional in scope.

TPL_asm2013_SEARCH

91145