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Dr. Dalbey is interested in the biogenesis of the inner membrane of Gram-negative bacteria, in particular the insertion of proteins into this membrane. His lab’s main focus is on the role of the YidC chaperone in the insertion, folding and assembly of inner membrane proteins. He is also seriously interested in the study of proteases involved in the cleavage of proteins and peptides that are transiently associated with cellular membranes. These proteases such as signal peptidase and signal peptide peptidases are crucially important for a wide range of essential biological processes.