Genes Found in H. pylori that Influence Biofilm Formation
Washington, DC – July 18, 2016 - Most bacteria cannot survive in the acidic environment of the human stomach, but Helicobacter pylori, a major cause of ulcers, thrives under such circumstances. Now research has shown that one of that bacterium’s regulatory proteins that helps it adapt to these stressful conditions also regulates the formation of biofilms. Biofilms, a group of bacteria that adhere together on a surface, are often much harder to kill than bacteria in their normal, disaggregated state, and can cause major medical problems. The research is published in the Journal of Bacteriology, a publication of the American Society for Microbiology.
Progress Towards Protection from Highly Lethal Ebola, Marburg Viruses
Washington, DC – July 12, 2016 – Ebola and Marburg filovirus disease outbreaks have typically occurred as isolated events, confined to central Africa. However, the recent Ebola epidemic spread to several African countries, and caused 11,000 deaths. That epidemic underscored the need to develop vaccines and therapeutics that could be used to fight future disease outbreaks. Now new research suggests that antibodies to filoviruses from individuals who have survived these diseases may offer protection—not only against the particular filovirus that infected an individual, but against other filoviruses, as well. The research is published in Clinical and Vaccine Immunology, a journal of the American Society for Microbiology.
Self-Prescribing Antibiotics is a Big Problem
Washington, DC – July 11, 2016 - Five percent of adults from a cohort of 400 people reported using antibiotics without a prescription during the previous 12 months. Twenty-five percent said they would use antibiotics without contacting a medical professional. These findings demonstrate yet another factor abetting the spread of antibiotic resistance. The research is published ahead of print July 11 in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.
New Resistance Gene Found in "High Risk" Multidrug-Resistant Pathogen
Washington, DC – July 11, 2016 – A team of Italian investigators has discovered a new variant of an emerging antibiotic resistance mechanism. The new variant, dubbed mcr-1.2, confers resistance to colistin, a last-resort antibiotic against multidrug-resistant Gram-negative pathogens. The research is published July 11, in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.
Colistin-Resistant Gene Detected in the U.S. for the Second Time: Investigators Alert to Its Possible Spread
Washington, DC - July 11, 2016 - For the second time, a clinical isolate of a bacterial pathogen has been detected in humans in the United States which carries the colistin resistance gene, mcr-1. This may also be the first case to show up in the US. That would be concerning because plasmids, genetic elements that are independent of the host genome, often jump between different bacterial species, spreading any resistance genes they carry. The research, the most comprehensive and contemporary surveillance data for mcr-1 to date, is published July 11 in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.
Boston Subway System Covered in Microbes, But They're Not Harmful
Washington, DC – June 28, 2016 – Boston’s subway system, known as the T, might be just as bacteria-laden as you’d expect but organisms found there are largely from normal human skin and incapable of causing disease, according to a study published June 28 in mSystems, an open access journal of the American Society for Microbiology.
Researchers Identify New Strategy for Decreasing Neonatal Mortality
Washington, DC - June 28, 2016 - Researchers have discovered how the bacteria Group B streptococcus (GBS) avoids detection by the immune system during pregnancy. The findings, reported in the journal mBio, could lead to the development of new drugs and strategies for treating GBS infection, which is a leading cause of neonatal morbidity and mortality.
Cross-respiration Between Oral Bacteria Leads to Worse Infections
Washington, D.C.—June 28, 2016—Researchers determined that two bacterial species commonly found in the human mouth and in abscesses, cooperate to make the pathogenic bacterium, Aggregatibacter actinomycetemcomitans, more infectious. Key to the cooperation is that the harmless partner provides the pathogen with an oxygen-rich environment that helps it flourish. The findings, published this week in mBio, an online open-access journal of the American Society for Microbiology, could lead to better ways to fight the majority of bacterial infections that play out within complex communities of bacteria.
Michigan Researchers Investigate What Causes Cattle to Shed STEC: Food Safety Could Benefit
Washington, DC - June 24, 2016 - Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens spread largely by cattle, that can cause hemorrhagic colitis and kidney failure. In an effort to find ways of reducing this problem, Michigan State University investigators show that stress, and the negative energy balance associated with lactation appear to encourage the shedding of STEC, especially in summer. The research is published ahead of print June 24 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.
Beneficial Bacteria May Protect Breasts From Cancer
Washington, DC - June 24, 2016 - Bacteria that have the potential to abet breast cancer are present in the breasts of cancer patients, while beneficial bacteria are more abundant in healthy breasts, where they may actually be protecting women from cancer, according to Gregor Reid, PhD, and his collaborators. These findings may lead ultimately to the use of probiotics to protect women against breast cancer. The research is published in the ahead of print June 24 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.