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Monday, 16 July 2018 12:04

Mr. CRISPR, Kevin Doxzen, Discusses the Revolutionary Gene Editing Technology

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Kevin Doxzen is a science communications specialist at the Innovative Genomics Institute in Berkeley, CA, associated with Dr. Jennifer Doudna. The Institute specializes in gene editing using CRISPR/Cas.

The CRISPR/Cas system evolved as a bacterial defense against virus attack, but it has been exploited primarily to manipulate the genomes of eukaryotes. CRISPR/Cas has already revolutionized gene editing, and has led to the creation of a large number of modified animals, which has led to ethical questions about human genome manipulation.

Dr. Doxzen talks about how CRISPR/Cas evolved, the various applications that is has been used for, some of the controversies associated with its use, and its further potential to improve human health.

The microCase for listeners to solve is about Nigel Tufnel, an aging rocker with a wild lifestyle who comes down with a life-threatening disease after going fishing in the Gulf of Mexico.


  • Karl Klose, Ph.D. (UTSA)
  • Kevin Doxzen, Ph.D. (Innovative Genomics Institute/U.C. Berkeley)
  • Janakiram Seshu, Ph.D. (UTSA)
  • Jesus Romo (UTSA)

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Last modified on Monday, 16 July 2018 16:25
Karl Klose

Karl Klose, Ph.D. is a Professor of Microbiology at the University of Texas San Antonio, the Director of the South Texas Center for Emerging Infectious Diseases (STCEID), and host of microTalk. He oversees the research on infectious diseases that is carried out in his laboratory by undergraduate, Masters’, and Ph.D. students, as well as research staff. He also teaches microbiology to undergraduate and graduate students.

Karl is enthusiastic about enlightening people to the fascinating world of microbes.  He has given two TED talks on antibiotic resistance. He has been a visiting professor in Kolkata India and Valparaiso Chile.  He has spent the past two years visiting ASM branch meetings through the Distinguished Lecturer program.  You can find Karl on Twitter and you can find STCEID on TwitterFacebook, and Instagram.