TWiM v3 275

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TWiM

This Week in Microbiology

As a science Professor at Columbia University, Racaniello has spent his academic career directing a research laboratory focused on viruses. His enthusiasm for teaching inspired him to reach beyond the classroom using new media. TWiM is for everyone who wants to learn about the science of microbiology in a casual way.

While there are no exams or pop quizzes, TWiM does encourage interaction with the audience via comments on specific episodes (below), vial email and voicemail at 908-312-0760. Listeners can also use MicrobeWorld to suggest topics for the show by submitting articles or papers to the site and tagging them with "TWiM". Each week Racaniello will view the tagged content and select items for discussion.

TWiM co-hosts include Elio SchaechterMichael Schmidt, and Michele Swanson.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Wednesday, 20 July 2016 16:59

Mice behaving badly - TWiM 131

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Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Saturday, 21 May 2016 00:01

A moonlighting phage protein - TWiM 128

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A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.

The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.

Thursday, 07 April 2016 18:27

A minimal cell operating system - TWiM 125

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A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.

Thursday, 24 March 2016 13:38

Fungal pirates - TWiM 124

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Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity. 

Wednesday, 09 March 2016 15:23

A microbial MAGE - TWiM 123

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Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.

Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome.

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