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TWiV

This Week in Virology

This Week in Virology (TWiV) is a podcast – or netcast, as some prefer to call them, since you don’t need an iPod to listen – about viruses. It was begun in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center. Their goal was to have an informal yet informative conversation about viruses which would be accessible to everyone, no matter what their science background. We wanted to eventually bring other virologists into the conversation, to make it more varied and interesting. Alan Dove, a science writer, joined us late in 2008, and Rich Condit, a poxvirologist, joined in 2009. We’ve had a number of guests on the show and we’re always trying to get more.

Why are we doing this? Dick, Rich, and I have spent our entire academic careers directing research laboratories, so we have a lot of knowledge to share. Plus, we both enjoy teaching. Put those two things together, and you have TWiV. If you want to learn about viruses in a relaxing way, then TWiV is for you.

Sunday, 07 October 2018 14:08

Staying below the ADAR - TWiV 514

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This years crop of Nobel Prizes, and how cells prevent leakage of mitochondrial double-stranded RNA into the cytoplasm, which would otherwise lead to the production of interferon. 

Sunday, 30 September 2018 13:59

Double-stranded in Belgium - TWiV 513

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From the 13th International Symposium on dsRNA viruses in Belgium, Vincent speaks with Harry Greenberg about his career and his work on rotaviruses, noroviruses, hepatitis B virus, and influenza virus.

Sunday, 23 September 2018 15:26

Flexuous SUMO wrestlers - TWiV 512

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Anne Simon joins the TWiV team to talk about plant viruses, including plum pox virus that devastates nut and stone fruit trees, and a geminivirus protein that regulates viral DNA synthesis. 

Sunday, 16 September 2018 15:39

Accessory found guilty in DC - TWiV 511

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Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.

Sunday, 09 September 2018 15:30

Retroviruses at Cold Spring Harbor - TWiV 510

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At the 44th Retrovirus meeting at Cold Spring Harbor Laboratories, with John Coffin, Stephen Hughes, Ya-Chi Ho, and Matt Takata talking about the meeting and their work on HIV-1.

Sunday, 02 September 2018 23:15

41,103 bases under the sea - TWiV 509

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The TWiV team considers whether those who can do, can’t teach, and newly discovered viruses of planarians and Aplysia with the largest RNA genomes.

Sunday, 26 August 2018 15:33

Bioweapon - TWiV 508

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A brief history of bioweapons, with a focus on the program in the Soviet Union, the largest ever undertaken, and his experience working in the decommissioned Soviet bioweapons laboratory known as Vector.

The biology of Ebola viruses, and how localization of the membrane proteins of vaccinia virus drive function: the fusion machinery sits at the tips of virions, and binding proteins are at the sides. 

Friday, 17 August 2018 14:52

David Tuller is PACEman - TWiV Special

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David Tuller returns to provide an update of his investigative work to expose the methodological and ethical problems with the PACE trial for ME/CFS.

How the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city by release of mosquitoes harboring Wolbachia.

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